M. (Matthias) Heinemann, Prof Dr

Professor

Faculty of Science and Engineering

Telephone:

+31 50 36 38146

+31 50 36 34165 (fax)

Sandra Haan, administrative assistant:

+31 50 36 34209

secbc rug.nl

E-mail:

m.heinemann rug.nl

Homepage ORCID Research Portal

Publications

Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle

Takhaveev, V. , Özsezen, S. , Smith, E. N. , Zylstra, A. , Chaillet, M. L. , Chen, H. , Papagiannakis, A. , Milias-Argeitis, A. & Heinemann, M. , 1-Feb-2023 , In: Nature Metabolism. 5 , 2 , p. 294-313 20 p.

Research output: Contribution to journal › Article › Academic › peer-review

Metabolic dynamics during the cell cycle

Zylstra, A. & Heinemann, M. , Jun-2022 , In: Current Opinion in Systems Biology. 30 , 9 p. , 100415.

Research output: Contribution to journal › Review article › peer-review

Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis

Van den Bergh, B. , Schramke, H. , Michiels, J. E. , Kimkes, T. E. P. , Radzikowski, J. L. , Schimpf, J. , Vedelaar, S. R. , Burschel, S. , Dewachter, L. , Lončar, N. , Schmidt, A. , Meijer, T. , Fauvart, M. , Friedrich, T. , Michiels, J. & Heinemann, M. , Jan-2022 , In: Nature Communications. 13 , 1 , 18 p. , 546.

Research output: Contribution to journal › Article › Academic › peer-review

Perspective: A stirring role for metabolism in cells

Losa, J. , Leupold, S. , Alonso-Martinez, D. , Vainikka, P. , Thallmair, S. , Tych, K. M. , Marrink, S. J. & Heinemann, M. , Apr-2022 , In: Molecular Systems Biology. 18 , 4 , 14 p. , e10822.

Research output: Contribution to journal › Review article › peer-review

The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor

Litsios, A. , Goswami, P. , Terpstra, H. M. , Coffin, C. , Vuillemenot, L-A. , Rovetta, M. , Ghazal, G. , Guerra, P. , Buczak, K. , Schmidt, A. , Tollis, S. , Tyers, M. , Royer, C. A. , Milias-Argeitis, A. & Heinemann, M. , 1-May-2022 , In: Molecular Biology of the Cell. 33 , 5 , 14 p. , rp2.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

A New Sugar for an Old Phage: a c-di-GMP-Dependent Polysaccharide Pathway Sensitizes Escherichia coli for Bacteriophage Infection

Sellner, B. , Prakapaitė, R. , van Berkum, M. , Heinemann, M. , Harms, A. & Jenal, U. , 14-Dec-2021 , In: Mbio. 12 , 6 , 17 p. , e03246-21.

Research output: Contribution to journal › Article › Academic › peer-review

A Robust Method for Generating, Quantifying, and Testing Large Numbers of Escherichia coli Persisters

Vedelaar, S. R. , Radzikowski, J. L. & Heinemann, M. , 30-Sept-2021 , In: Methods in molecular biology (Clifton, N.J.). 2357 , p. 41-62 22 p.

Research output: Contribution to journal › Article › Academic › peer-review

A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux

Ortega, A. D. , Takhaveev, V. , Vedelaar, S. R. , Long, Y. , Mestre-Farràs, N. , Incarnato, D. , Ersoy, F. , Olsen, L. F. , Mayer, G. & Heinemann, M. , 18-Nov-2021 , In: Cell Chemical Biology. 28 , 11 , p. 1554-1568.e8 15 p. , j.chembiol.2021.04.006.

Research output: Contribution to journal › Article › Academic › peer-review

Mass spectrometry-based metabolomics: A guide for annotation, quantification and best reporting practices

Alseekh, S., Aharoni, A., Brotman, Y., Contrepois, K., D'Auria, J., Ewald, J., C Ewald, J., Fraser, P. D., Giavalisco, P., Hall, R. D., Heinemann, M. , Link, H., Luo, J., Neumann, S., Nielsen, J., Perez de Souza, L., Saito, K., Sauer, U., Schroeder, F. C., Schuster, S., & 12 others Siuzdak, G. , Skirycz, A. , Sumner, L. W. , Snyder, M. P. , Tang, H. , Tohge, T. , Wang, Y. , Wen, W. , Wu, S. , Xu, G. , Zamboni, N. & Fernie, A. R. , Jul-2021 , In: Nature Methods. 18 , 7 , p. 747-756 10 p.

Research output: Contribution to journal › Review article › peer-review

Physical bioenergetics: Energy fluxes, budgets, and constraints in cells

Yang, X. , Heinemann, M. , Howard, J. , Huber, G. , Iyer-Biswas, S. , Le Treut, G. , Lynch, M. , Montooth, K. L. , Needleman, D. J. , Pigolotti, S. , Rodenfels, J. , Ronceray, P. , Shankar, S. , Tavassoly, I. , Thutupalli, S. , Titov, D. V. , Wang, J. & Foster, P. J. , 29-Jun-2021 , In: Proceedings of the National Academy of Sciences of the United States of America. 118 , 26 , 10 p. , e2026786118.

Research output: Contribution to journal › Article › Academic › peer-review