prof. dr. M.G. (Marianne) Rots

Professor of Molecular Epigenetics

Faculty of Medical Sciences

Telephone:

+31 50 361 0153

+31 50 361 8043 (Secretariat)

+31 50 361 9911 (fax)

E-mail:

m.g.rots umcg.nl

Homepage ORCID Research Portal

Publications

The Mitochondrial Epigenome: An Unexplored Avenue to Explain Unexplained Myopathies?

Mposhi, A. , Liang, L. , Mennega, K. P. , Yildiz, D. , Kampert, C. , Hof, I. H. , Jellema, P. G. , de Koning, T. J. , Faber, K. N. , Ruiters, M. H. J. , Niezen-Koning, K. E. & Rots, M. G. , 16-Feb-2022 , In: International Journal of Molecular Sciences. 23 , 4 , 19 p. , 2197.

Research output: Contribution to journal › Article › Academic › peer-review

Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes

Lifelines Cohort Study, VA Million Veteran Program, Pazoki, R., Vujkovic, M., Elliott, J., Evangelou, E., Gill, D., Ghanbari, M., van der Most, P. J. , Pinto, R. C., Wielscher, M., Farlik, M., Zuber, V., de Knegt, R. J., Snieder, H. , Uitterlinden, A. G., Lynch, J. A., Jiang, X., Said, S., Kaplan, D. E.& 17 others , Lee, K. M. , Serper, M. , Carr, R. M. , Tsao, P. S. , Atkinson, S. R. , Dehghan, A. , Tzoulaki, I. , Ikram, M. A. , Herzig, K. H. , Järvelin, M. R. , Alizadeh, B. Z. , O'Donnell, C. J. , Saleheen, D. , Voight, B. F. , Chang, K. M. , Thursz, M. R. & Elliott, P. , 10-May-2021 , In: Nature Communications. 12 , 1 , 12 p. , 2579.

Research output: Contribution to journal › Article › Academic › peer-review

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis

Tognoli, M. L. , Vlahov, N. , Steenbeek, S. , Grawenda, A. M. , Eyres, M. , Cano-Rodriguez, D. , Scrace, S. , Kartsonaki, C. , von Kriegsheim, A. , Willms, E. , Wood, M. J. , Rots, M. G. , van Rheenen, J. , O'Neill, E. & Pankova, D. , 18-Oct-2021 , In: The EMBO Journal. 40 , 20 , 23 p. , 107680.

Research output: Contribution to journal › Article › Academic › peer-review

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1

Fledderus, J. , Vanchin, B. , Rots, M. G. & Krenning, G. , 5-Feb-2021 , In: Journal of personalized medicine. 11 , 2 , 21 p. , 103.

Research output: Contribution to journal › Review article › Academic › peer-review

Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCHL1 suppresses epithelial-mesenchymal transition and is under-expressed in cadmium-transformed human bronchial epithelial cells

Wu, D-D. , Xu, Y-M. , Chen, D-J. , Liang, Z-L. , Chen, X-L. , Hylkema, M. N. , Rots, M. G. , Li, S-Q. & Lau, A. T. Y. , Aug-2021 , In: Cell biology and toxicology. 37 , 4 , p. 497–513 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

Advances of epigenetic editing

Gjaltema, R. A. F. & Rots, M. G. , Aug-2020 , In: Current Opinion in Chemical Biology. 57 , p. 75-81 7 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions

Mossel, D. M. , Moganti, K. , Riabov, V. , Weiss, C. , Kopf, S. , Cordero, J. , Dobreva, G. , Rots, M. G. , Klüter, H. , Harmsen, M. C. & Kzhyshkowska, J. , 2-Jun-2020 , In: Frontiers in Immunology. 11 , 19 p. , 1071.

Research output: Contribution to journal › Article › Academic › peer-review

Exploiting epigenetics for the treatment of inborn errors of metabolism

Rutten, M. G. S. , Rots, M. G. & Oosterveer, M. H. , Jan-2020 , In: Journal of Inherited Metabolic Disease. 43 , 1 , p. 63-70 8 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Hoofdstuk Epigenetica

Rots, M. , 26-Mar-2020 , Neurowetenschappen voor de Klinische Psychiatrie. van den Heuvel, O., van der Werf, Y., Schmand, B. & Sabbe, B. (eds.). Boom uitgevers

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and is Resilient to TGFβ1 Activation

Gjaltema, R. A. F. , Goubert, D. , Huisman, C. , Pilar García Tobilla, C. D. , Koncz, M. , Jellema, P. G. , Wu, D. , Brouwer, U. , Kiss, A. , Verschure, P. J. , Bank, R. A. & Rots, M. G. , 21-May-2020 , In: International Journal of Molecular Sciences. 21 , 10 , 24 p. , 3634.

Research output: Contribution to journal › Article › Academic › peer-review