prof. dr. M.G. (Marianne) Rots

Hoogleraar Moleculaire Epigenetica

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 0153

050 361 8043 (Secretariaat)

050 361 9911 (fax)

E-mail:

m.g.rots umcg.nl

Homepage ORCID Research Portal

Publicaties

Cell-specific DNA methylation in human alpha and beta cells regulates gene expression in type 2 diabetes

Ofori, J. K., Ruhrmann, S., Lindström, A., Perfilyev, A., Martin, M., Karagiannopoulos, A., Scisciola, L., Kost, K., Jönsson, J., Nilsson, Å., Kantor, B., Dudenhöffer-Pfeifer, M., Rots, M. G., Wendt, A., Rönn, T., Eliasson, L., Bacos, K. & Ling, C., apr.-2026, In: Nature Metabolism. 8, 4, blz. 957-980 24 blz.

Onderzoeksoutput › › peer review

Epigenetic editing: from concept to clinic

Heller, E. A., Bintu, L. & Rots, M. G., mrt.-2026, In: Nature Reviews Drug Discovery. 25, blz. 227-248 22 blz.

Onderzoeksoutput › peer review

Epigenetic editing to advance CAR T cell therapy

Horvathova, L., Rots, M. G. & Wiersma, V. R., 23-feb.-2026, (E-pub ahead of print) In: Clinical Epigenetics.

Onderzoeksoutput › peer review

Epigenetic signatures and cellular stress response pathways in metabolic dysfunction-associated steatotic liver disease: a personalized medicine perspective

Cortés-Mancera, F. M., Rots, M. G., Moshage, H. & Arroyave-Ospina, J. C., 2026, In: Frontiers in Physiology. 17, blz. 1787963

Onderzoeksoutput › peer review

Nanopore Electroporation: A New Delivery Method Within the Field of Epigenetic Editing

Ekstrand, F., Ruhrmann, S., Bacos, K., Bartel, S., Jellema, P., Rots, M. G., Ling, C. & Prinz, C. N., 26-mrt.-2026, (E-pub ahead of print) In: Small. blz. e13858

Onderzoeksoutput › › peer review

Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS

Liang, L., González Molina, L. A., Jellema, P. G., van Faassen, M., Otten, L. T. A., Mennega, K. P., Hof, I. H., Dijck-Brouwer, D. A. J., Dolga, A. M., Rots, M. G. & Niezen-Koning, K. E., 11-sep.-2025, In: International Journal of Molecular Sciences. 26, 18, 18 blz., 8864.

Onderzoeksoutput › › peer review

Epigenetic editing and epi-drugs: a combination strategy to simultaneously target KDM4 as a novel anticancer approach

Sarno, F., Jacob, J. J., Eilers, R. E., Nebbioso, A., Altucci, L. & Rots, M. G., 19-jun.-2025, In: Clinical Epigenetics. 17, 1, 16 blz., 105.

Onderzoeksoutput › › peer review

The Promise of Epigenetic Editing for Treating Brain Disorders

González Molina, L. A., Dolga, A. M., Rots, M. G. & Sarno, F., 17-jan.-2025, Neuroepigenetics Mechanisms in Health and Disease. van Zundert, B. & Montecino, M. (reds.). Springer, blz. 111-190 80 blz. (Subcellular Biochemistry; vol. 108).

Onderzoeksoutput › › peer review

Toward designer magic bullets: Epigenetic editing to empower CAR T cells

Horvathova, L., Wiersma, V. R. & Rots, M. G., 9-dec.-2025, In: Molecular Therapy Nucleic Acids. 36, 4, 3 blz., 102700.

Onderzoeksoutput › › peer review

Changes in histone lysine acetylation, but not DNA methylation during facultative hibernation in Syrian hamster liver

Oosterhof, M. M., Coussement, L., van Pijkeren, A., Kwiatkowski, M., Zwinderman, M. R. H., Dekker, F. J., de Meyer, T., Reitsema, V. A., Bischoff, R., Guryev, V., Bouma, H. R., Henning, R. H. & Rots, M. G., sep.-2024, In: Epigenetics Communications. 4, 1, 14 blz., 1.

Onderzoeksoutput › › peer review