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dr. J.V. Koomen

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Faculteit Medische Wetenschappen/UMCG

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E-mail:

j.v.koomen umcg.nl

ORCID Research Portal

Publicaties

Evaluating Model‐Based Extrapolation of Plasma Exposure for Long‐Acting Injectable Products: From Single‐ to Multiple‐Dose Trials

Lubberts, D. E., Eleveld, D. J., Verscheijden, L. F. M., Colin, P. J. & Koomen, J. V., feb-2026, In: CPT: Pharmacometrics & Systems Pharmacology. 15, 2, 9 blz., e70170.

Onderzoeksoutput › › peer review

Model‐Informed Approaches for Pediatric Type 2 Diabetes Evidence Generation: Insights from a Model‐Based Longitudinal HbA1c Meta‐Analysis from EMA Marketing Authorization Applications

Colin, P. J., Manolis, E. & Koomen, J. V., 1-sep-2026, (E-pub ahead of print) In: Clinical Pharmacology & Therapeutics.

Onderzoeksoutput › › peer review

OpenPMX Software for Nonlinear Mixed-Effect Models in Pharmacometrics: Precision Compared With NONMEM First-Order Conditional Estimation

Eleveld, D. J., Koomen, J. V., Stevens, J., Colin, P. J. & Struys, M. M. R. F., jun-2026, In: CPT: Pharmacometrics & Systems Pharmacology. 15, 6, 11 blz., e70250.

Onderzoeksoutput › › peer review

Should a pharmacokinetic model be more than its data?

Maton, L. C. H., Valk, B. I., Struys, M. M. R. F., Koomen, J. V. & Eleveld, D. J., 18-aug-2026, (E-pub ahead of print) In: British Journal of Anaesthesia.

Onderzoeksoutput › › peer review

A Population Pharmacokinetic Analysis for Piperacillin/Tazobactam in Patients with End-Stage Kidney Disease Undergoing Intermittent Haemodialysis: Extension of a General-Purpose Model

Kong, D., Koomen, J. V., Vanommeslaeghe, F., Delanghe, S., Van Biesen, W., Colin, P. J. & Eloot, S., aug-2025, In: Clinical Pharmacokinetics. 64, 14 blz., e0157923.

Onderzoeksoutput › › peer review

A review on the role of extrapolation as basis for paediatric marketing authorization applications of medicines in the EU

Simons, C. W. M., Maton, L. C. H., van Dartel, M., van den Heuvel, M., den Otter, L., Versantvoort, C., Colin, P. J. & Koomen, J. V., 2025, In: British Journal of Clinical Pharmacology. 91, 5, blz. 1500-1510 11 blz.

Onderzoeksoutput › › peer review

Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedation

Eleveld, D. J., Colin, P. J., Van den Berg, J. P., Koomen, J. V., Stoehr, T. & Struys, M. M. R. F., jul-2025, In: British Journal of Anaesthesia. 135, 1, blz. 206-217 12 blz.

Onderzoeksoutput › › peer review

Influence of remifentanil on the pharmacokinetics and pharmacodynamics of remimazolam in healthy volunteers

Vellinga, R., Koomen, J. V., Eleveld, D. J., Stöhr, T., Pesic, M., Struys, M. M. R. F. & Colin, P., apr-2025, In: Anesthesiology. 142, 4, blz. 666-679 14 blz.

Onderzoeksoutput › › peer review

Pharmacokinetics and pharmacodynamics of remimazolam for procedural sedation in children and adolescents

Colin, P. J., Bichajian, L. H., Curt, V. R., Koomen, J. V., Stöhr, T., Struys, M. M. R. F. & Mason, K. P., aug-2025, In: Anesthesiology. 143, 2, blz. 368-382 15 blz.

Onderzoeksoutput › › peer review

Target controlled infusion in the intensive care unit: a scoping review

Introna, M., Carozzi, C., Gentile, A., Girasole, R., Gemma, M., Koomen, J. V., Struys, M. M. R. F. & van Den Berg, J. P., 9-sep-2025, In: Journal of Clinical Monitoring and Computing. 15 blz.

Onderzoeksoutput › peer review

Alle (35) publicaties

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