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About us Practical matters How to find us J.E.M.N. Klein, Dr

Research interests

The scientific activities combine the fields of experimental (bio)inorganic chemistry with elements from organic, physical and computational/theoretical chemistry. Projects either follow an experimental route where at relevant points computational chemistry is used to support the analysis of our findings, or at times we will perform experiments to validate concepts that we have derived from computational/theoretical work. It is the development of concepts that reconcile experiment and theory and enable unambiguous communication between these areas of work that is of vital importance for my approach to research.

Oxidation Chemistry – From Mechanism to Methodology

The primary focus of the research activities that provides a general underlying theme is our interest in catalysts for oxidation chemistry. Challenging transformations, such as the C-H oxidation of (saturated) hydrocarbons, oxygenation of organic compounds and halogenation reactions are addressed. The two transition metals that take center stage are gold and iron. More recently, photochemically driven catalysis has entered the portfolio of transformations in which I have a strong interest. Through mechanistically driven method development we break the traditional boundaries of the intrinsic research areas in chemistry and open new vistas.

The four main research lines that we pursue are:

(i) Iron Chemistry

 (ii) Gold Chemistry

 (iii) Oxidation States

 (iv) Electron Flow in Chemical Transformations

Publications

NMR and Mössbauer Studies Reveal a Temperature-Dependent Switch from S = 1 to 2 in a Nonheme Oxoiron(IV) Complex with Faster C-H Bond Cleavage Rates

A Porphyrin Iron(III) π-Dication Species and its Relevance in Catalyst Design for the Umpolung of Nucleophiles

How reduced are nucleophilic gold complexes?

Revisiting sp2 Dilithio Methandiides: From Geometric Curiosity to Simple Bonding Description

Spectroscopic Manifestations and Implications for Catalysis of Quasi-d10 Configurations in Formal Gold(III) Complexes.

Understanding the Surprising Oxidation Chemistry of Au−OH Complexes

Fluorinated click-derived tripodal ligands drive spin crossover in both iron(II) and cobalt(II) complexes

Formation and Reactivity of a Fleeting NiIII Bisphenoxyl Diradical Species

Gold-Aluminyl and Gold-Diarylboryl Complexes: Bonding and Reactivity with Carbon Dioxide

Gold(III) Catalyzed Overman Rearrangements: Controlling Steric Interactions using Pincer-Type Ligands

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