dr. I.R. Holtman

E-mail:
i.r.holtman umcg.nl

Research

Publications
  1. Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

    Nott, A., Holtman, I. R., Coufal, N. G., Schlachetzki, J. C. M., Yu, M., Hu, R., Han, C. Z., Pena, M., Xiao, J., Wu, Y., Keulen, Z., Pasillas, M. P., O'Connor, C., Nickl, C. K., Schafer, S. T., Shen, Z., Rissman, R. A., Brewer, J. B., Gosselin, D., Gonda, D. D., Levy, M. L., Rosenfeld, M. G., McVicker, G., Gage, F. H., Ren, B. & Glass, C. K., 29-Nov-2019, In : Science. 366, 6469, p. 1134-1139 50 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function

    Link, V. M., Duttke, S. H., Chun, H. B., Holtman, I. R., Westin, E., Hoeksema, M. A., Abe, Y., Skola, D., Romanoski, C. E., Tao, J., Fonseca, G. J., Troutman, T. D., Spann, N. J., Strid, T., Sakai, M., Yu, M., Hu, R., Fang, R., Metzler, D., Ren, B. & Glass, C. K., 14-Jun-2018, In : Cell. 173, 7, p. 1796-1809.e17 31 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. A novel microglial subset plays a key role in myelinogenesis in developing brain

    Wlodarczyk, A., Holtman, I. R., Krueger, M., Yogev, N., Bruttger, J., Khorooshi, R., Benmamar-Badel, A., de Boer-Bergsma, J. J., Martin, N. A., Karram, K., Kramer, I., Boddeke, E. W. G. M., Waisman, A., Eggen, B. J. L. & Owens, T., 15-Nov-2017, In : The EMBO Journal. 36, 22, p. 3292-3308 17 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Transcriptional control of microglia phenotypes in health and disease

    Holtman, I. R., Skola, D. & Glass, C. K., 1-Sep-2017, In : CLIN Journal. 127, 9, p. 3220-3229 10 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  5. Increased white matter inflammation in aging- and Alzheimer's disease brain

    Raj, D., Yin, Z., Breur, M., Doorduin, J., Holtman, I., Olah, M., Otter, I. M., van Dam, D., de Deyn, P., Den Dunnen, W., Eggen, B., Amor, S. & Boddeke, E., Jun-2017, In : Frontiers in Molecular Neuroscience. 10, 18 p., 206.

    Research output: Contribution to journalMeeting AbstractAcademic

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