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About us Practical matters How to find us prof. dr. I.M. (Irene) van Langen

University Medical Center Groningen

prof. dr. I.M. (Irene) van Langen

Professor Clinical Genetics

Faculty of Medical Sciences

Telephone:

+31 50 361 7209

b.smid@medgen.umcg.nl:

+31 50 361 7159

E-mail:

i.m.van.langen umcg.nl

Homepage ORCID Research Portal

Research interests

ELSI: Ethical Legal Social Issues in (Clinical) Genetics and genetic screening in the Next Generation Sequencing Era

Publications

Comprehensive Recommendations for the Clinical Management of Pregnant Women With Noninvasive Prenatal Test Results Suspicious of a Maternal Malignancy

The Dutch NIPT Consortium, Heesterbeek, C. J., Lenaerts, L., Tjan-Heijnen, V. C. G., Amant, F., van Rij, M. C., Theunis, M., de Die-Smulders, C. E. M., Vermeesch, J. R. & Macville, M. V. E., 1-Aug-2024, In: JCO oncology practice. 20, 8, p. 1027-1034 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Development of a digital risk-prediction tool based on family health history for the general population: legal and ethical implications

Dijkstra, T., Ploem, M. C., van Langen, I. M., Sieperda, B. M. Y., Zaal, J., Lucassen, A. M., Maeckelberghe, E. L. M. & Christiaans, I., 14-Dec-2024, (E-pub ahead of print) In: Journal of community genetics. 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Perceptions of reproductive healthcare providers regarding their involvement in offering expanded carrier screening in fertility clinics: a qualitative study

Klein, D., van Dijke, I., van Langen, I. M., Dondorp, W., Lakeman, P., Henneman, L. & Cornel, M. C., Jul-2024, In: Reproductive Biomedicine Online. 49, 1, 10 p., 103857.

Research output: Contribution to journal › Article › Academic › peer-review

Prenatal cell-free DNA testing of women with pregnancy-associated cancer: a retrospective cross-sectional study

The Dutch NIPT Consortium, Heesterbeek, C. J., Tjan-Heijnen, V. C. G., Heimovaara, J. H., Lenaerts, L., Lok, C., Vriens, I. J. H., Van Opstal, D., Boon, E. M. J., Sie, D., de Die-Smulders, C. E. M., Amant, F. & Macville, M. V. E., Oct-2024, In: The Lancet Regional Health - Europe. 45, 101024.

Research output: Contribution to journal › Article › Academic › peer-review

Primary care professionals' views on population-based expanded carrier screening: an online focus group study

van den Heuvel, L. M., Woudstra, A. J., van der Hout, S., Jans, S., Wiersma, T., Dondorp, W., Birnie, E., Lakeman, P., Henneman, L., Plantinga, M. & van Langen, I. M., Aug-2024, In: Family practice. 41, 4, p. 571–578 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Systematic reanalysis of genomic data by diagnostic laboratories: a scoping review of ethical, economic, legal and (psycho)social implications

van der Geest, M. A., Maeckelberghe, E. L. M., van Gijn, M. E., Lucassen, A. M., Swertz, M. A., van Langen, I. M. & Plantinga, M., May-2024, In: European Journal of Human Genetics. 32, 5, p. 489-497 9 p.

Research output: Contribution to journal › Review article › peer-review

Predicting personal cardiovascular disease risk based on family health history: Development of expert-based family criteria for the general population

Dijkstra, T., van den Heuvel, L. M., van Tintelen, J. P., van der Werf, C., van Langen, I. M. & Christiaans, I., Dec-2023, In: European Journal of Human Genetics. 31, p. 1381–1386 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Rapid exome sequencing as a first-tier test in neonates with suspected genetic disorder: results of a prospective multicenter clinical utility study in the Netherlands

on behalf of RADICON-NL consortium, Olde Keizer, R. A. C. M., Marouane, A., Kerstjens-Frederikse, W. S., Deden, A. C., Lichtenbelt, K. D., Jonckers, T., Vervoorn, M., Vreeburg, M., Henneman, L., de Vries, L. S., Sinke, R. J., Pfundt, R., Stevens, S. J. C., Andriessen, P., van Lingen, R. A., Nelen, M., Scheffer, H., Stemkens, D. & Oosterwijk, C.& 5 others, van Amstel, H. K. P., de Boode, W. P., van Zelst-Stams, W. A. G., Frederix, G. W. J. & Vissers, L. E. L. M., Jun-2023, In: European Journal of Pediatrics. 182, 6, p. 2683-2692 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Societal implications of expanded universal carrier screening: a scoping review

van den Heuvel, L. M., van den Berg, N., Janssens, A. C. J. W., Birnie, E., Henneman, L., Dondorp, W. J., Plantinga, M. & van Langen, I. M., Jan-2023, In: European Journal of Human Genetics. 31, 1, p. 55-72 18 p.

Research output: Contribution to journal › Review article › peer-review

A couple based approach to expanded carrier screening in a fertility setting

Schuurmans, J., Plantinga, M., Fenwick, A., van Langen, I. & Lucassen, A., Apr-2022, In: European Journal of Human Genetics. 30, SUPPL 1, p. 573-573 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

All (181) publications

Press/media

Aanbieden UMCG-dragerschapstest via getrainde huisarts is verantwoord

van Langen, I. & Schuurmans, J.

22/06/2021

Press/Media: Expert Comment › Popular

Genetici UMC Groningen willen proef met test naar erfelijke ziektes voor alle wensouders

van Langen, I.

21/06/2021

Press/Media: Expert Comment › Popular

Link to ELSI website (including news, publications in non-academic media and radio/tv

Langen, van, I.

04/01/2021

Press/Media: Other › Popular

All (3) press/media

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