Skip to ContentSkip to Navigation
Over ons Praktische zaken Waar vindt u ons I. Braga Dias

Research interests

Growing up in the Amazon rainforest, I developed a deep appreciation for biological diversity and natural healing. Early encounters with indigenous healers sparked my curiosity about the therapeutic potential of nature, a fascination that evolved into a passion for molecular biology. Inspired by my high school mentor, I pursued a degree in biotechnology, where I discovered my true calling—harnessing nature’s molecular secrets to drive innovation in medicine.

My academic journey led me to Rutgers University, where I earned a BSc (Honours) in Biotechnology. During my time there, I conducted research under Dr. Joan Bennett, a distinguished genetic microbiologist, investigating solutions for white-nose syndrome in hibernating bats. Through this experience, I gained valuable expertise in experimental design, proposal writing, and scientific communication, culminating in my honors thesis as part of the George H. Cook Scholars Program.

However, my growing interest in regenerative medicine, gene therapy, and stem cell research drove me to pursue a Master’s in Molecular Medicine and Innovative Treatments (MMIT) at the University of Groningen. During this time, I explored cutting-edge technologies such as human induced pluripotent stem cells (hiPSCs), 3D-engineered cardiac tissue (ECT), and salivary gland organoids through hands-on research. These experiences solidified my commitment to developing transformative biomedical solutions.

Now, as a PhD candidate, I focus on investigating the molecular mechanisms of anthracycline-induced cardiotoxicity using hiPSC-derived cardiomyocytes and 3D ECT models. My work integrates molecular biology, tissue engineering, and precision medicine to uncover novel cardioprotective strategies. Passionate about bridging fundamental research with clinical applications, I aim to contribute to the advancement of innovative therapies that improve patient outcomes.

Publicaties

Dantrolene as a Potential Strategy to Prevent Doxorubicin-Induced Cardiotoxicity: Mechanistic Promise and Clinical Prospects

A review of the pathophysiological mechanisms of doxorubicin-induced cardiotoxicity and aging

Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues

Unraveling the Big Sleep: Molecular Aspects of Stem Cell Dormancy and Hibernation