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How to find us I.A. (Izabela) Rodenhuis-Zybert

Research interests

My team within the Experimental Virology Group focuses on immune mechanisms triggered by acute viral infections. Specifically, we try to understand the mechanisms governing the differences between the balanced and unbalanced inflammation induced by the infections.  Currently, our primary goal is to identify points of control in inflammation in the course of dengue virus, chikungunya virus and SARS-CoV-2 infection. Importantly, through national and international collaborations with basic and clinical scientists, we foster the multidisciplinary approach to these infections.

Next to research, I enjoy teaching biology of viral infections. Herewith I hope to excite new generations to pursue science in the fields of virology and immunology.

Publications

Antibody-independent functions of B cells during viral infections

Direct Infection of B Cells by Dengue Virus Modulates B Cell Responses in a Cambodian Pediatric Cohort

Moxidectin and ivermectin inhibit sars-cov-2 replication in vero e6 cells but not in human primary airway epithelium cells

Regulation of innate immune responses in macrophages differentiated in the presence of vitamin D and infected with dengue virus 2

Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells

Tomatidine reduces chikungunya virus progeny release by controlling viral protein expression

Chikungunya virus requires an intact microtubule network for efficient viral genome delivery

Serotonergic Drugs Inhibit Chikungunya Virus Infection at Different Stages of the Cell Entry Pathway

TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Tomatidine, a natural steroidal alkaloid shows antiviral activity towards chikungunya virus in vitro

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