prof. dr. H.J. (Hiddo) Lambers Heerspink

Clinical Pharmacologist

Faculty of Medical Sciences

Telephone:

+31 50 361 7859

E-mail:

h.j.lambers.heerspink umcg.nl

ORCID Research Portal

Publications

Effects of Dapagliflozin on Health-Related Quality of Life in Patients with CKD

Bakker, W. M., Heerspink, H. J. L., Jongs, N., Correa-Rotter, R., Rossing, P., Toto, R. D., Wheeler, D. C., McMurray, J. J. V., Langkilde, A. M., Gansevoort, R. T., Chertow, G. M. & Vart, P., Jan-2026, In: Journal of the American Society of Nephrology. 37, 1, p. 101-109 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from DAPA-CKD and FIGARO-DKD

de la Rambelje, M. A., Voors, A. A., Greasley, P. J., Berger, M. & Heerspink, H. J. L., Jan-2026, In: Diabetes, Obesity and Metabolism. 28, 1, p. 750-753 4 p.

Research output: Contribution to journal › Letter (Research letter) › Academic › peer-review

Adjunct-to-insulin therapy using SGLT2 inhibitors in youth with type 1 diabetes: a randomized controlled trial

Mahmud, F. H., Bjornstad, P., Clarson, C., Clarke, A., Anthony, S. J., Curtis, J., Elia, Y. T., McArthur, L., Mertens, L., Moineddin, R., Kirsch, S., Coles, N., Maione, M., Furman, M., Babalola, F., Tommerdahl, K. L., Harrington, J., Riddell, M. C., Prasad, P. & Huang, L., Heerspink, H. J. L. & Cherney, D. Z. I., Jul-2025, In: Nature medicine. 31, 7, p. 2317-2324 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Albuminuria Responses to Dapagliflozin in Patients With Type 2 Diabetes: A Crossover Trial

Beernink, J., Jongs, N., Doelman, C., Laverman, G. & Heerspink, H., 24-Mar-2025, In: Jama network open. 8, 3, 11 p., e251689.

Research output: Contribution to journal › Article › Academic › peer-review

A Strategic Roadmap to Support Communication on and Acceptance of Surrogate Endpoints: The REnal Surrogacy accEpTance in Chronic Kidney Disease (RESET CKD) Collaboration

Garcia Sanchez, J. J., Trapero-Bertran, M., Ciani, O., Detournay, B., Gesualdo, L., Heerspink, H. J. L., Inker, L. A., Sinha, S., Wanner, C., Little, D. J., Sinsakul, M., Nam, Y. S. & Taylor, R. S., Nov-2025, In: Advances in therapy. 42, 11, p. 5727-5741 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Authors' Reply: Effects of Zibotentan and Dapagliflozin on Fluid Retention in Patients with CKD: Need More Evidence

Heerspink, H. J. L. & Smeijer, J. D., Feb-2025, In: Journal of the American Society of Nephrology. 36, 2, p. 324 1 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Authors’ Reply: Unlocking the Potential of SC0062: A New Horizon in IgA Nephropathy Treatment?

Chen, J. & Heerspink, H. J. L., Apr-2025, In: Journal of the American Society of Nephrology. 36, 4, p. 746 1 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Canagliflozin and iron metabolism in the CREDENCE trial

Koshino, A., Heerspink, H. J. L., Jongs, N., Badve, S. V., Arnott, C., Neal, B., Jardine, M., Mahaffey, K. W., Pollock, C., Perkovic, V., Hansen, M. K., Bakker, S. J. L., Wada, T. & Neuen, B. L., 1-Apr-2025, In: Nephrology Dialysis Transplantation. 40, 4, p. 696-706 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Canagliflozin reduces oral loop diuretic intensification in patients with type 2 diabetes: A participant-level pooled analysis of the CANVAS and CREDENCE trials

Chatur, S., Vaduganathan, M., Fletcher, R. A., Perkovic, V., Heerspink, H., Arnott, C., Pollock, C., Mahaffey, K. W., Neal, B., Jardine, M., Solomon, S. D. & Neuen, B. L., Jun-2025, In: European Journal of Heart Failure. 27, 6, p. 994-1002 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Cardiovascular, kidney and safety outcomes with canagliflozin in older adults: A combined analysis from the CANVAS Program and CREDENCE trial

Siriwardana, A., Buizen, L., Jun, M., Kotwal, S., Arnott, C., Jardine, M. J., Levin, A., Heerspink, H. J. L., Charytan, D. M., Pollock, C., Perkovic, V. & Neuen, B. L., Apr-2025, In: Diabetes, Obesity and Metabolism. 27, 4, p. 1972-1979 8 p.

Research output: Contribution to journal › Article › Academic › peer-review