dr. H.H.W. (Herman) Sillje

Hoofd Experimenteel Cardiologisch Laboratorium

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 5339

E-mail:

h.h.w.sillje umcg.nl

Research Portal

Publicaties

Nanoparticle-Mediated Delivery of Adenosine 5′-Monophosphate Enhances 5-Oxoprolinase Activity to Mitigate Oxidative Stress in Heart Failure

Esquivel-Gaytan, A., Bomer, N., Bartolo, R., Arevalo-Gomez, K. F., Deiman, F. E., Bras, M., Honarnejad, S., Permentier, H., Dömling, A., Voors, A. A., A. Santos, H., Silljé, H. H. W. & Van der Meer, P., jan.-2026, In: Advanced Therapeutics. 9, 1, 16 blz., e00263.

Onderzoeksoutput: Article › › peer review

Cardiac remodeling pathways do not accelerate disease onset and severity in a mouse model of PLN-R14del cardiomyopathy

Sun, L., Schouten, E. M., Gomez, K. A., Teixeira, V. O. N. & Silljé, H. H. W., 9-okt.-2025, In: Scientific Reports. 15, 1, 11 blz., 35393.

Onderzoeksoutput: Article › › peer review

Combination of Captopril, Ambrisentan and Sildenafil mitigates long-term side effects of combined heart and lung irradiation

Wiedemann, J., Brouwer, U., Sillje, H., Dickinson, M., Coppes, R. P. & van Luijk, P., mei-2025.

Onderzoeksoutput ›

Combination of Captopril, Ambrisentan and Sildenafil mitigates long-term side effects of combined heart and lung irradiation

Wiedemann, J., Brouwer, U., Sillje, H., Dickinson, M., Coppes, R. P. & van Luijk, P., 2025.

Onderzoeksoutput ›

Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70−/− mice

de Vries, H. D., Eijgenraam, T. R., Bloks, V. W., Mulder, N. L., van Zutphen, T., Silljé, H. H. W., Kuipers, F. & de Boer, J. F., 2025, In: Pediatric Research. 97, blz. 2145–2152 8 blz.

Onderzoeksoutput: Article › › peer review

Glutathione deficiency and heart failure: a systematic review of human and animal evidence

Al-Mubarak, A. A., Esquivel-Gaytan, A., Silljé, H. H. W., van der Meer, P. & Bomer, N., jun.-2025, In: Advances in Redox Research. 15, 12 blz., 100131.

Onderzoeksoutput: Review article › peer review

In PLN-R14del mice, SR structure restoration, rather than calcium cycling, is the dominant effector of PLN-ASO treatment

Sun, L., Eijgenraam, T. R., Amilon, C., Janzén, D., Hansson, K. M., Kubli, D. A., Später, D., Mullick, A. E., van der Meer, P., Nunes Teixeira, V. O. & Silljé, H. H. W., 1-okt.-2025, In: Cardiovascular Research. 121, 13, blz. 2042-2054 13 blz.

Onderzoeksoutput: Article › › peer review

Myocardial ketone body oxidation contributes to empagliflozin-induced improvements in cardiac contractility in murine heart failure

Voorrips, S. N., Palm, C. L., Saucedo-Orozco, H., Mahmoud, B., Schouten, E. M., Feringa, A. M., Sanchez-Aguilera, P. I., Nijholt, K. T., Yurista, S. R., van der Meer, P., Silljé, H. H. W. & Westenbrink, B. D., jul.-2025, In: European Journal of Heart Failure. 27, 7, blz. 1353-1358 6 blz.

Onderzoeksoutput: Article › › peer review

Nicotinamide-N-methyltransferase inhibition improves cardiac function and structure in a heart failure with preserved ejection fraction mouse model

Li, S., Rodrigues, P. G., Chakraborty, A. D., Correia, C., Schouten, E. M., Strömstedt, M., Löfgren, L., Persson, M., Fredlund, L., Rohman, M., Bergström, F., Akerud, T., Ericson, C., Kreisel, K., Guzman, M. M., Silljé, H. H. W., de Boer, R. A. & Meems, L. M. G., jul.-2025, In: Pharmacological research. 217, 15 blz., 107820.

Onderzoeksoutput: Article › › peer review

RNA Therapeutics in Heart Failure

Deiman, F. E., de Graaf, M. M., Sillje, H. H. W., Grote Beverborg, N., Bomer, N. & van der Meer, P., 30-okt.-2025, (E-pub ahead of print) In: Journal of cardiovascular translational research. 15 blz.

Onderzoeksoutput: Review article › peer review