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How to find us dr. G. (Gert) Luurtsema

Research interests

Gert Luurtsema meets the UMCG requirements for Principal Investigator. His research focused on a broad range of topics, ranging from tracer development to validation of clinical imaging applications. With support of NWO-STW funding, he has accomplished a research line on imaging of the blood-brain barrier (BBB) integrity in relation to brain disorders and drug delivery. Besides this, he is supervising 7 PhD students, 5 master students and 3 postdocs. Currently, he is (co-)author of more than 85 peer-reviewed scientific articles in high ranking journals and scientific textbooks (h-index 27). He was guest editor of the journals Current Pharmaceutical Design and Contrast Media & Molecular Imaging. 

Publications

A new approach to produce [F-18]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function

Basic aspects of good manufacturing practice for PET-rediopharmaceuticals

Corrigendum: Modular Medical Imaging Agents Based on Azide-Alkyne Huisgen Cycloadditions: Synthesis and Pre-Clinical Evaluation of F-18-Labeled PSMA-Tracers for Prostate Cancer Imaging (vol 26, pg 10871, 2020)

Cross-coupling of [11C]methyllithium for 11C-labelled PET tracer synthesis

EANM guideline for harmonisation on molar activity or specific activity of radiopharmaceuticals: impact on safety and imaging quality

Evaluation of P-glycoprotein function at the blood-brain barrier using [F-18]MC225-PET

First clinical assessment of [ 18 F]MC225, a novel fluorine-18 labelled PET tracer for measuring functional P-glycoprotein at the blood-brain barrier

Head-to-head comparison of (R)-[C-11]verapamil and [F-18]MC225 in non-human primates, tracers for measuring P-glycoprotein function

In Vivo Induction of P-Glycoprotein Function can be Measured with [F-18]MC225 and PET

PET Imaging of ABC Transporters at the Blood-Brain Barrier

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Press/media

Diagnosi di malattie cerebrali oggi se ne parla a Triggiano

Diagnose van prostaatkanker bij Treant op topniveau