dr. G. (Gert) Luurtsema

dr. G. (Gert) Luurtsema
E-mail:
g.luurtsema umcg.nl

Research

Research interests

Gert Luurtsema meets the UMCG requirements for Principal Investigator. His research focused on a broad range of topics, ranging from tracer development to validation of clinical imaging applications. With support of NWO-STW funding, he has accomplished a research line on imaging of the blood-brain barrier (BBB) integrity in relation to brain disorders and drug delivery. Besides this, he is supervising 7 PhD students, 5 master students and 3 postdocs. Currently, he is (co-)author of more than 85 peer-reviewed scientific articles in high ranking journals and scientific textbooks (h-index 27). He was guest editor of the journals Current Pharmaceutical Design and Contrast Media & Molecular Imaging. 

Publications
  1. Induced expression of P-gp and BCRP transporters on brain endothelial cells using transferrin functionalized nanostructured lipid carriers: A first step of a potential strategy for the treatment of Alzheimer's disease

    Arduino, I., Iacobazzi, R. M., Riganti, C., Lopedota, A. A., Perrone, M. G., Lopalco, A., Cutrignelli, A., Cantore, M., Laquintana, V., Franco, M., Colabufo, N. A., Luurtsema, G., Contino, M. & Denora, N., Oct-2020, In : International Journal of Pharmaceutics. p. 1-9 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. IAEA contribution to the development of copper-64 radiopharmaceuticals for theranostic applications

    Jalilian, A., Osso, J., Vera-Araujo, J., Kumar, V., Harris, M., Gutfilen, B., Guerin, B., Li, H., Zhuravlev, F., Chakravarty, R., Alirezapour, B., Avila-Rodriguez, M., Khan, I., Aljammaz, I., Assaad, T., Luurtsema, G., Smith, J. & Duatti, A., 7-Oct-2020, In : Quarterly Journal of Nuclear Medicine and Molecular Imaging.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Establishing the production of clinically relevant PET tracers via Ru-mediated 18F-deoxyfluorination

    Santos Clemente, dos, G., Rickmeier, J., Luurtsema, G., Ritter, T. & Elsinga, P. H., 28-Aug-2020. 2 p.

    Research output: Contribution to conferenceAbstractAcademic

  4. Pharmacokinetic modelling of [18F]MC225 for quantification of P-glycoprotein function at the blood-brain barrier in non-human primates with PET

    García-Varela, L., Arif, W. M., Vállez García, D., Kakiuchi, T., Ohba, H., Harada, N., Tago, T., Elsinga, P. H., Tsukada, H., Colabufo, N. A., Dierckx, R. A. J. O., van Waarde, A., Toyohara, J., Boellaard, R. & Luurtsema, G., 5-Aug-2020, In : Molecular pharmaceutics. 17, 9, p. 3477-3486 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Automated synthesis, preclinical toxicity, and radiation dosimetry of [F-18]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier

    Toyohara, J., Sakata, M., Tago, T., Colabufo, N. A. & Luurtsema, G., 22-Jul-2020, In : EJNMMI Research. 10, 1, 11 p., 84.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (110) »

Press / Media
  1. Diagnosi di malattie cerebrali oggi se ne parla a Triggiano

    Gert Luurtsema

    17/02/2020

    1 Media contribution

    Press/Media: Expert CommentAcademic

  2. Diagnose van prostaatkanker bij Treant op topniveau

    Gert Luurtsema

    08/05/2019

    1 Media contribution

    Press/Media: Expert CommentAcademic

View all (2) »

Activities
  1. PET imaging of P-glycoprotein at the blood-brain barrier with new 18F tracers.

    Philip H. Elsinga (Supervisor), Albert D. Windhorst (Supervisor), Geert Luurtsema (Co-supervisor) & Jon D. Laman (Examiner)

    10-Sep-2018

    Activity: ExaminationSupervision of PhD studentsAcademic

  2. BBBNedwork meeting

    Gert Luurtsema (Organiser)

    15-Mar-2019

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

  3. Dipartimento di Farmacia-Scienze del Farmaco, Universita degli Studi di Bari, Bari

    Gert Luurtsema (Visiting researcher)

    2019

    Activity: Visiting an external institutionVisiting an external academic institutionAcademic

View all (11) »

Prizes
  1. Top 5 best publications in 2018 by the Journal of the American Society of Nephrology

    Harmke Bos (Recipient), Vallez Garcia, David (Recipient), Kuipers, Hannie (Recipient), Elting, Jan Willem (Recipient), Marcel J.H. Aries (Recipient), Krijnen, Wim (Recipient), Groen, Henk (Recipient), Willemsen, Antoon (Recipient), Laar, van, Peter Jan (Recipient), Strijkert, Fijanne (Recipient), Luurtsema, Gert (Recipient), Slart, Riemer (Recipient), Westerhuis, Ralf (Recipient), Gansevoort, Ron (Recipient), Gaillard, Carolus (Recipient) & Franssen, Casper (Recipient), 2019

    PrizeAcademic

  2. Publication Price 2018 for established researchers

    Harmke Polinder-Bos (Recipient), Vallez Garcia, David (Recipient), Kuipers, Hannie (Recipient), Elting, Jan Willem (Recipient), Marcel J.H. Aries (Recipient), Krijnen, Wim (Recipient), Groen, Henk (Recipient), Willemsen, Antoon (Recipient), Laar, van, Peter Jan (Recipient), Strijkert, Fijanne (Recipient), Luurtsema, Gert (Recipient), Slart, Riemer (Recipient), Westerhuis, Ralf (Recipient), Gansevoort, Ron (Recipient), Gaillard, Carolus (Recipient) & Franssen, Casper (Recipient), Mar-2019

    PrizeAcademic

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