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How to find us dr. G. (Gert) Luurtsema

Research interests

Gert Luurtsema meets the UMCG requirements for Principal Investigator. His research focused on a broad range of topics, ranging from tracer development to validation of clinical imaging applications. With support of NWO-STW funding, he has accomplished a research line on imaging of the blood-brain barrier (BBB) integrity in relation to brain disorders and drug delivery. Besides this, he is supervising 7 PhD students, 5 master students and 3 postdocs. Currently, he is (co-)author of more than 85 peer-reviewed scientific articles in high ranking journals and scientific textbooks (h-index 27). He was guest editor of the journals Current Pharmaceutical Design and Contrast Media & Molecular Imaging. 

Publications

Cross-coupling of [11C]methyllithium for 11C-labelled PET tracer synthesis

PET Imaging of ABC Transporters at the Blood-Brain Barrier

Pharmacokinetic Modeling of (R)-[11C]verapamil to Measure the P-Glycoprotein Function in Nonhuman Primates

Automated synthesis, preclinical toxicity, and radiation dosimetry of [F-18]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier

Changes in cerebral oxygenation and cerebral blood flow during hemodialysis - A simultaneous near-infrared spectroscopy and positron emission tomography study

Establishing the production of clinically relevant PET tracers via Ru-mediated 18F-deoxyfluorination

Evaluation of a Novel P-glycoprotein Inducer Using [18F]MC225 and PET

Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography

IAEA contribution to the development of copper-64 radiopharmaceuticals for theranostic applications

Induced expression of P-gp and BCRP transporters on brain endothelial cells using transferrin functionalized nanostructured lipid carriers: A first step of a potential strategy for the treatment of Alzheimer's disease

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Press/media

Diagnosi di malattie cerebrali oggi se ne parla a Triggiano

Diagnose van prostaatkanker bij Treant op topniveau