dr. G. (Gert) Luurtsema

Telefoon:

E-mail:

g.luurtsema umcg.nl

Research interests

The research of Gert Luurtsema, associate professor at the UMCG, is focused on a broad range of topics, ranging from tracer development to validation of clinical imaging applications. With support of NWO-STW funding, he has accomplished a research line on imaging of the blood-brain barrier (BBB) integrity in relation to brain disorders and drug delivery. Besides this, he is supervising > 7 PhD students, 5 master students and 3 postdocs. Currently, he is (co-)author of more than 100 peer-reviewed scientific articles in high ranking journals and scientific textbooks. He was guest editor of the journals Current Pharmaceutical Design and Contrast Media & Molecular Imaging.

Publicaties

Functional PET imaging of gut microbiota with [18F]fluorodeoxyglucose, [18F]fluorodeoxysorbitol and [11C]choline reflects Clostridia and Lactobacillales abundance in caecum and small intestine and host metabolic interactions

La Rosa, F., Guzzardi, M. A., Conti, G., Petroni, D., Pardo Tendero, M., Bernardi, S., Barone, M., Panetta, D., Tedeschi, L., Fabbri, C., Casavecchia, F., Riabitch, D., Granziera, F., Ragusa, R., Caselli, C., Giorgetti, A., Campani, D., Baglini, E., Menichetti, L. & Elsinga, P., Luurtsema, G., Brigidi, P. & Iozzo, P., aug-2026, In: European Journal of Nuclear Medicine and Molecular Imaging. 53, blz. 6111-6127 17 blz.

Onderzoeksoutput: Article › › peer review

Minimally Invasive [18F]MC225 Quantification Using LAFOV PET: A Simulation Study

Providência, L., van der Weijden, C. W. J., Somsen, J. F., Mossel, P., De Souza, G. S., Dierckx, R. A. J. O., Luurtsema, G., Lammertsma, A. A. & Tsoumpas, C., 11-mrt-2026, (E-pub ahead of print) In: IEEE Transactions on Radiation and Plasma Medical Sciences. 11 blz.

Onderzoeksoutput: Article › › peer review

Pittsburgh compound B positron emission tomography detects cardiomyopathy in hereditary transthyretin amyloidosis patients with negative bone scintigraphy: a pilot study

Tingen, H. S. A., Stormezand, G. N., van Snick, P., Hu, Y., Van Der Zwaag, P., Oerlemans, M., van der Meer, P., Hazenberg, B. P. C., Luurtsema, G., Nienhuis, H. L. A. & Slart, R. H. J. A., 2026, In: Frontiers in Nuclear Medicine. 6, 7 blz., 1747625.

Onderzoeksoutput: Article › › peer review

Simultaneous [15O]H2O and [89Zr]mAb Scanning with Long Axial Field-of-View PET: A Simulation Study Using Digital Twins

Li, Z., Mohr, P., Dao, V., Luurtsema, G., Brouwers, A. H., Lammertsma, A. A. & Tsoumpas, C., mrt-2026, In: IEEE Transactions on Radiation and Plasma Medical Sciences. 10, 3, blz. 406 - 417 12 blz.

Onderzoeksoutput: Article › › peer review

Validation of a Deep-Learning Coregistration Framework for Long-Axial-Field-of-View PET/CT Using Low-Radiation-Exposure Protocols Across Various Tracers

Li, Z., Providência, L., Mohr, P., Mostafapour, S., Roya, M., Martinez-Lucio, T. S., Somsen, J. F., van Leeuwen, G. L., Salvi De Souza, G., van Sluis, J., Glaudemans, A. W. J. M., Dierckx, R. A. J. O., de Vries, J.-P. P. M., Luurtsema, G., Slart, R. H. J. A., Brouwers, A. H., Schleyer, P., Conti, M., Lammertsma, A. A.& Schaefferkoetter, J., Tsoumpas, C., mei-2026, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 67, 5, blz. 810-816 7 blz.

Onderzoeksoutput: Article › › peer review

Designing a Small Molecule for PET Radiotracing: [18F]MC225 in Human Trials for Early Diagnosis in CNS Pathologies

Mastropasqua, F., Luurtsema, G., Filosa, C. & Colabufo, N. A., sep-2025, In: Molecules. 30, 18, 25 blz., 3696.

Onderzoeksoutput: Review article › peer review

DSC Perfusion MRI Artefact Reduction Strategies: A Short Overview for Clinicians and Scientific Applications

van der Weijden, C. W. J., Gutmann, I. W., Somsen, J. F., Luurtsema, G., van der Goot, T., Arzanforoosh, F., Kramer, M. C. A., Buunk, A. M., de Vries, E. F. J., Rauscher, A. & van der Hoorn, A., 6-jul-2025, In: Journal of Clinical Medicine. 14, 13, 19 blz., 4776.

Onderzoeksoutput: Review article › peer review

Evaluating image-derived input functions for cerebral [18F]MC225 PET studies

Salvi de Souza, G., Mossel, P., Somsen, J. F., Providência, L., Bartels, A. L., Willemsen, A. T. M., Dierckx, R. A. J. O., Furini, C. R. G., Lammertsma, A. A., Tsoumpas, C. & Luurtsema, G., 19-mei-2025, In: Frontiers in Nuclear Medicine. 5, 11 blz., 1597902.

Onderzoeksoutput: Article › › peer review

Exploratory Study of Sex Differences in P-Glycoprotein Function at the Blood–Brain Barrier

Salvi de Souza, G., Liu, W., Mossel, P., Somsen, J. F., Bartels, A. L., Furini, C. R. G., Lammertsma, A. A., Tsoumpas, C. & Luurtsema, G., apr-2025, In: Clinical and translational science. 18, 4, 9 blz., e70196.

Onderzoeksoutput: Article › › peer review

Mapping cardiac drug transport: In vitro assessment of cardiac P-glycoprotein function with [18F]MC225 by using µ-engineered heart tissues.

Liu, W., Dannenberg, M., Mossel, P., Cai, Z., Farinha Antunes, I., Sijbesma, J., Kwizera, C., Cao, L., van der Meer, A., Passier, R., Slart, R. H. J. A., Schwach, V. & Luurtsema, G., nov-2025, In: European Heart Journal Open. 5, 6, 11 blz., oeaf150.

Onderzoeksoutput: Article › › peer review