prof. dr. G.J. (Gerrit) Poelarends

Hoogleraar Farmaceutische Biotechnologie Directeur Groningen Research Institute of Pharmacy (GRIP)

Faculteit Science and Engineering

Telefoon:

050 36 33354

E-mail:

g.j.poelarends rug.nl

ORCID Research Portal

Publicaties

Correction to “Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells”Article link copied!

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 27-mrt.-2025, In: Journal of Medicinal Chemistry. 68, 6, blz. 6844-6845 2 blz.

Onderzoeksoutput

Engineered C-N Lyases for Stereoselective Synthesis of Tertiary Amines

Bothof, L., Gong, X., Onclin, M. E., Fodran, P. & Poelarends, G. J., 18-aug.-2025, In: Angewandte Chemie (International ed. in English). 64, 34, 7 blz., e202507311.

Onderzoeksoutput: Article › › peer review

Engineering 2-Deoxy-D-ribose-5-phosphate Aldolase for anti- and syn-Selective Epoxidations of α,β-Unsaturated Aldehydes

Zhou, H., Kunzendorf, A., Xu, G., Frietema, H. O. T., Thunnissen, A.-M. W. H. & Poelarends, G. J., 12-mei-2025, In: Angewandte Chemie (International ed. in English). 64, 20, 7 blz., e202503054.

Onderzoeksoutput: Article › › peer review

Expanding the Substrate Scope of C−N Lyases by Homologue Discovery

Bothof, L., Iacovelli, R., Tepper, P. G. & Poelarends, G. J., 1-apr.-2025, In: ChemBioChem. 26, 7, 8 blz., e202500068.

Onderzoeksoutput: Article › › peer review

Flavin-Dependent Nitroreductases: Privileged Enzymes for Chemical and Photochemical Synthesis

Russo, S., Luján, A. P., Fraaije, M. W. & Poelarends, G. J., 6-mrt.-2025, In: ChemCatChem. 17, 5, 19 blz., e202401304.

Onderzoeksoutput › peer review

Nitroreductase-triggered indazole formation

Terholsen, H., Medema, L., Chernyshova, E., Luján, A. P., Poelarends, G. J. & Schmidt, S., 14-feb.-2025, (Submitted) ChemRxiv.

Onderzoeksoutput: Voordruk ›

Biochemical, kinetic, and structural characterization of a Bacillus tequilensis nitroreductase

Russo, S., Rozeboom, H. J., Wijma, H. J., Poelarends, G. J. & Fraaije, M. W., 1-sep.-2024, In: The FEBS Journal. 291, 17, blz. 3889 - 3903 15 blz., 17210.

Onderzoeksoutput: Article › › peer review

Exploiting Nitroreductases for the Tailored Photoenzymatic Synthesis of Structurally Diverse Heterocyclic Compounds

Luján, A. P., Bhat, M. F., Marko, E. E. A., Fodran, P. & Poelarends, G. J., 8-okt.-2024, In: Chemistry – A European Journal. 30, 56, 18 blz., e202402380.

Onderzoeksoutput: Article › › peer review

Exploration of Hydrazide-Based HDAC8 PROTACs for the Treatment of Hematological Malignancies and Solid Tumors

Zhao, C., Zhang, J., Zhou, H., Setroikromo, R., Poelarends, G. & Dekker, F., 22-aug.-2024, In: Journal of Medicinal Chemistry. 67, 16, blz. 14016–14039 24 blz.

Onderzoeksoutput: Article › › peer review