dr. F. (Frank) Klont

Universitair Docent in Gepersonaliseerde Farmacotherapie

Faculteit Science and Engineering

Telefoon:

06 3192 1379

Faculteit Medische Wetenschappen/UMCG

Telefoon:

E-mail:

frank.klont rug.nl

Homepage ORCID Research Portal

Publicaties

Inter-species variability in 4,4'-methylenedianiline metabolism: Insights from human and rat precision-cut liverslices

Hof, M. A. J., Sewdihal, J., Stepanovic, S., Hermans, J. H., Horvatovich, P., Olinga, P. & Klont, F., mrt.-2026, In: Regulatory toxicology and pharmacology. 166, 9 blz., 106034.

Onderzoeksoutput: Article › › peer review

Intra-erythrocyte creatine, plasma creatine and long-term outcomes in stable kidney transplant recipients: Results from the TransplantLines Biobank and Cohort study

TransplantLines Investigators, Doorenbos, C. S. E., Post, A., van der Veen, Y., Franssen, C. F. M., Eisenga, M. F., Dullaart, R. P. F., Navis, G., Wu, Q., Gonzalez-Delgado, J. M., Connelly, M. A. & Bakker, S. J. L., feb.-2026, In: Clinical Nutrition Open Science. 65, 17 blz., 100606.

Onderzoeksoutput: Article › › peer review

Symptom Burden and Patient-Reported Outcomes in Kidney Transplant Recipients: Results From the TransplantLines Biobank and Cohort Studies

TransplantLines Investigators, Riemersma, N. L., Knobbe, T. J., Kremer, D., Nolte, S., Bültmann, U., Annema, C., Shehab, N. B. N., Eisenga, M. F., Berger, S. P., Bakker, S. J. L. & Nieuwenhuijs, G. J., jan.-2026, In: Kidney Medicine. 8, 1, 11 blz., 101168.

Onderzoeksoutput: Article › › peer review

A pharmacological view on accounting for pharmacokinetic factors in the estimation of pharmaceutical emissions based on drug usage data: Comment on: Zillien C et al., Assessing city-wide pharmaceutical emissions to wastewater via modelling and passive sampling, Envir Int. vol. 185, March 2024, 108524

Klont, F., Bellinga, J. S., Giunchi, V., Balafas, S. & Hak, E., feb.-2025, In: Environment international. 196, 3 blz., 109312.

Onderzoeksoutput › › peer review

Dose, Kidney Function, and a Drug-Excipient Interaction Impair Mycophenolate Mofetil Prodrug Activation in Kidney Transplant Recipients

TransplantLines Investigators, Nijdam, F. B., Hof, M. A. J., Kremer, D., Knobbe, T. J., Hopfgartner, G., Bakker, S. J. L., Hak, E. & Klont, F., jul.-2025, In: European journal of drug metabolism and pharmacokinetics. 50, blz. 341–352 12 blz.

Onderzoeksoutput: Article › › peer review

Farmacofenotypering versterkt de farmacogenetica.

Klont, F., Manson, M. L. & Swen, J. J., 2025, In: Pharmaceutisch Weekblad. 14, blz. 14-16 3 blz.

Onderzoeksoutput: Article ›

Geneesmiddelinteracties en farmacogenetica: (nu nog) twee gescheiden werelden.

Huisman, R., Groenendijk, W., van den Berg, T. & Klont, F., 2025, In: Pharmaceutisch Weekblad. 19, blz. 18-20 3 blz.

Onderzoeksoutput: Article ›

Insights in Cellular and Molecular Signatures of the Small Intestinal Graft Posttransplantation: Successful, Recovered, and Rejected - A Case Series

TransplantLines Investigators, Karmi, N., Oelen, R., Bigaeva, E., De Jong, S., Haveman, J. W., Van Der Heide, F., Hermoso, M. A., Van Der Wijst, M. G. P., Kats-Ugurlu, G., Weersma, R. K., Festen, E. A. M., Uniken Venema, W. T. C. & Dijkstra, G., 24-apr.-2025, (E-pub ahead of print) In: Transplantation. 10 blz.

Onderzoeksoutput: Article › › peer review

Pharmacometabolomics Detects Various Unreported Metoprolol Metabolites in Urine of (Potential) Living Kidney Donors and Kidney Transplant Recipients

TransplantLines Investigators, Heddema, W. A., Hof, M. A. J., Sosnowski, P., Bakker, S. J. L., Hopfgartner, G. & Klont, F., mei-2025, In: Clinical Pharmacokinetics. 64, 5, blz. 779-789 11 blz.

Onderzoeksoutput: Article › › peer review

Pharmacometabolomics Enables Real-World Drug Metabolism Sciences

TransplantLines Investigators, Nijdam, F. B., Hof, M. A. J., Blokzijl, H., Bakker, S. J. L., Hak, E., Hopfgartner, G. & Klont, F., jan.-2025, In: Metabolites. 15, 1, 14 blz.

Onderzoeksoutput: Article › › peer review