prof. dr. F.J. (Frank) Dekker

Associate professor Pharmaceutical Epigenetics

Faculty of Science and Engineering

Telephone:

+31 50 36 38030 (0031-50-3638030)

+31 6 3192 1118 (0031-6-31921118)

E-mail:

f.j.dekker rug.nl

Homepage ORCID Research Portal

Publications

Discovery of highly potent HDAC8 PROTACs with anti-tumor activity

Zhao, C. , Chen, D. , Suo, F. , Setroikromo, R. , Quax, W. J. & Dekker, F. , 17-Apr-2023 , In: Bioorganic Chemistry. 136 , 16 p. , 106546.

Research output: Contribution to journal › Article › Academic › peer-review

Novel inhibitors of histone deacetylase (hdac), and methods, compositions and uses related thereto

Zwinderman, R. H. & Dekker, F. J. , 26-Jan-2023 , Patent No. WO2023003468, 22-Jul-2022 , Priority date 23-Jul-2021

Research output: Patent

Rational Design in Photopharmacology with Molecular Photoswitches

Kobauri, P. , Dekker, F. J. , Szymanski, W. & Feringa, B. L. , 4-May-2023 , (E-pub ahead of print) In: Angewandte Chemie - International Edition. e202300681.

Research output: Contribution to journal › Review article › peer-review

4-Iodopyrimidine labeling reveals nuclear translocation and nuclease activity for both MIF and MIF2

Xiao, Z. , Chen, D. , Mulder, F. , Song, S. , van der Wouden, P. E. , Cool, R. H. , Melgert, B. N. , Poelarends, G. J. & Dekker, F. J. , 3-Jan-2022 , In: Chemistry. 28 , 1 , e202103030.

Research output: Contribution to journal › Article › Academic › peer-review

Discovery of chromene compounds as inhibitors of PvdQ acylase of Pseudomonas aeruginosa

Vogel, J. G. T. , Wibowo, J. P. , Fan, H. , Setroikromo, R. , Wang, K. , Dömling, A. , Dekker, F. J. & Quax, W. J. , 27-Oct-2022 , In: Microbes and infection. 24 , 7 p. , 105017.

Research output: Contribution to journal › Article › Academic › peer-review

Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury

Song, S. , Xiao, Z. , Dekker, F. J. , Poelarends, G. J. & Melgert, B. N. , Feb-2022 , In: Cellular and molecular life sciences. 79 , 2 , p. 105 19 p. , 105.

Research output: Contribution to journal › Review article › peer-review

Novel Design Strategies to Enhance the Efficiency of Proteolysis Targeting Chimeras

Zhao, C. & Dekker, F. J. , 2022 , In: ACS Pharmacology & Translational Science. 5 , 9 , p. 710-723 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d -Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

Xiao, Z. , Osipyan, A. , Song, S. , Chen, D. , Schut, R. A. , van Merkerk, R. , van der Wouden, P. E. , Cool, R. H. , Quax, W. J. , Melgert, B. N. , Poelarends, G. J. & Dekker, F. J. , 10-Feb-2022 , In: Journal of Medicinal Chemistry. 65 , 3 , p. 2059-2077

Research output: Contribution to journal › Article › Academic › peer-review

Adsorptive Microtiter Plates As Solid Supports in Affinity Purification Workflows

Klont, F. , Kwiatkowski, M. , Faiz, A. , van den Bosch, T. , Pouwels, S. D. , Dekker, F. J. , Ten Hacken, N. H. T. , Horvatovich, P. & Bischoff, R. , 5-Nov-2021 , In: Journal of Proteome Research. 20 , 11 , p. 5218–5221 4 p.

Research output: Contribution to journal › Letter › Academic › peer-review

Biaryl sulfonamides as cisoid azosteres for photopharmacology

Kobauri, P. , Szymanski, W. , Cao, F. , Thallmair, S. , Marrink, S. J. , Witte, M. D. , Dekker, F. J. & Feringa, B. L. , 27-Apr-2021 , In: Chemical Communications. 57 , 34 , p. 4126-4129 4 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (125) publications

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