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Publications

Exploration of Hydrazide-Based HDAC8 PROTACs for the Treatment of Hematological Malignancies and Solid Tumors

Small Molecule MIF Modulation Enhances Ferroptosis by Impairing DNA Repair Mechanisms

The synthesis of 1,2,3-triazoles as binders of D-dopachrome tautomerase (D-DT) for the development of dual-targeting inhibitors

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos

Discovery of highly potent HDAC8 PROTACs with anti-tumor activity

First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8

Histone Deacetylase 3-Directed PROTACs Have Anti-inflammatory Potential by Blocking Polarization of M0-like into M1-like Macrophages

Identification and Characterization of a Small Molecule that Activates Thiosulfate Sulfurtransferase and Stimulates Mitochondrial Respiration

Novel inhibitors of histone deacetylase (hdac), and methods, compositions and uses related thereto

Protocol of the Double-Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins

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Press/media

Finalisten van ‘Life Science Innovation Award’ zijn bekend

University of Groningen: Open Competition Science-M Grants For Krushynska And Dekker

Financiering voor ontwikkeling van innovatieve inhalatietherapie voor COPD-patiënten

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