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About us Practical matters How to find us E. (Edita) Jurak, Dr

Research interests

The research done in the Bioproduct Engineering (BE) unit focuses on the biocatalysis and enzyme discovery for modification of complex polymers such as carbohydrates and plastics.

The more fundamental research is directed towards understanding how microbial enzymes work and work together (gene clusters) to modify given polymers. Large focus area is understanding enzyme function, structure and properties, studying natural diversity of enzymes, and getting insights into the changes of the polymer structure and physical properties upon the enzyme’s action.

Examples are 1) the biosynthesis and structure of NanoGlycogen from the red microalgae Galdieria sulphuraria, the structure-function relationship of GH13 and GH57 microbial glycogen branching enzymes. 2) unravelling the function of uncharacterized enzymes from xylan related GH families and enzymes of unknown function (UNKs) from bacterial gene clusters trough transcriptomic and sequence analysis and in-depth biochemical characterization.

Publications

A novel acetyl xylan esterase enabling complete deacetylation of substituted xylans

Occurrence and function of enzymes for lignocellulose degradation in commercial Agaricus bisporus cultivation

Alpha-1,4-transglycosylation Activity of GH57 Glycogen Branching Enzymes Is Higher in the Absence of a Flexible Loop with a Conserved Tyrosine Residue

Novel β-galactosidase activity and first crystal structure of Glycoside Hydrolase family 154

The Synergistic Effect of GH13 and GH57 GBEs of Petrotoga mobilis Results in α-Glucan Molecules with a Higher Branch Density

Efficient isolation of membrane-associated exopolysaccharides of four commercial bifidobacterial strains

Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans

PACER: a novel 3D plant cell wall model for the analysis of non-catalytic and enzymatic responses

The influence of amylose content on the modification of starches by glycogen branching enzymes

5-Hydroxy-2-Methylfurfural from Sugar Beet Thick Juice: Kinetic and Modeling Studies

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