E.V. Bigaeva

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e.bigaeva rug.nl

Publications

Macromolecular Crowding as a Tool to Screen Anti-fibrotic Drugs: The Scar-in-a-Jar System Revisited

Puerta Cavanzo, N. , Bigaeva, E. , Boersema, M. , Olinga, P. & Bank, R. A. , 14-Jan-2021 , In: Frontiers in Medicine. 7 , 14 p. , 615774.

Research output: Contribution to journal › Article › Academic › peer-review

Exploring organ-specific features of fibrogenesis using murine precision-cut tissue slices

Bigaeva, E. , Gore, E. , Mutsaers, H. A. M. , Oosterhuis, D. , Kim, Y. O. , Schuppan, D. , Bank, R. A. , Boersema, M. & Olinga, P. , 1-Jan-2020 , In: Biochimica et biophysica acta-Molecular basis of disease. 1866 , 1 , 14 p. , 165582.

Research output: Contribution to journal › Article › Academic › peer-review

Inhibition of tyrosine kinase receptor signaling attenuates fibrogenesis in an ex vivo model of human renal fibrosis

Bigaeva, E. , Stribos, E. G. D. , Mutsaers, H. A. M. , Piersma, B. , Leliveld, A. M. , de Jong, I. J. , Bank, R. A. , Seelen, M. A. , van Goor, H. , Wollin, L. , Olinga, P. & Boersema, M. , Jan-2020 , In: American journal of physiology-Renal physiology. 318 , 1 , p. F117-F134 18 p.

Research output: Contribution to journal › Article › Academic › peer-review

Investigating fibrosis and inflammation in an ex vivo NASH murine model

Gore, E. , Bigaeva, E. , Oldenburger, A. , Jansen, Y. J. M. , Schuppan, D. , Boersema, M. , Rippmann, J. F. , Broermann, A. & Olinga, P. , Feb-2020 , In: American Journal of Physiology. Gastrointestinal and Liver Physiology. 318 , 2 , p. G336-G351 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis

Bigaeva, E. , Puerta Cavanzo, N. , Stribos, E. G. D. , de Jong, A. J. , Biel, C. , Mutsaers, H. A. M. , Jensen, M. S. , Nørregaard, R. , Leliveld, A. M. , de Jong, I. J. , Hillebrands, J-L. , van Goor, H. , Boersema, M. , Bank, R. A. & Olinga, P. , 18-May-2020 , In: Pharmaceutics. 12 , 5 , 31 p. , 459.

Research output: Contribution to journal › Article › Academic › peer-review

Survival and cellular heterogeneity of epithelium in cultured mouse and rat precision-cut intestinal slices

Biel, C. , Bigaeva, E. , Hesse, M. , Bomers, J. J. M. , van Summeren, K. , Teunis, M. A. T. , Vaessen, S. , Ten Klooster, J. P. & Olinga, P. , Dec-2020 , In: Toxicology in Vitro. 69 , 104974.

Research output: Contribution to journal › Article › Academic › peer-review

Understanding human gut diseases at single-cell resolution

Bigaeva, E. , Uniken Venema, W. T. C. , Weersma, R. K. & Festen, E. A. M. , 15-Sep-2020 , In: Human Molecular Genetics. 29 , R1 , p. R51-R58 8 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Ex vivo fibrosis research: 5 mm closer to human studies

Bigaeva, E. , 2019 , [Groningen]: University of Groningen . 301 p.

Research output: Thesis › Thesis fully internal (DIV)

Growth factors of stem cell niche extend the life-span of precision-cut intestinal slices in culture: A proof-of-concept study

Bigaeva, E. , Bomers, J. J. M. , Biel, C. , Mutsaers, H. A. M. , de Graaf, I. A. M. , Boersema, M. & Olinga, P. , Sep-2019 , In: Toxicology in Vitro. 59 , p. 312-321 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

PI3K inhibition reduces murine and human liver fibrogenesis in precisioncut liver slices

Gore, E. , Bigaeva, E. , Oldenburger, A. , Ook, K. Y. , Rippmann, J. F. , Schuppan, D. , Boersema, M. & Olinga, P. , Nov-2019 , In: Biochemical Pharmacology. 169 , 12 p. , 113633.

Research output: Contribution to journal › Article › Academic › peer-review

All (18) publications

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