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breed in kennis  -  sterk in techniek
Over ons Praktische zaken Waar vindt u ons D. (Danny) Incarnato, PhD

Publicaties

Condition-dependent amorphous protein agglomerates control cytoplasmic rheology

FIRST-seq: a nanopore-based cDNA sequencing platform for RNA modification and structure profiling

Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis

Rational design of hammerhead ribozymes as CD93 silencing tools for vascular diseases

RNA functional modulation by Mitoxantrone via RNA structural ensemble repartitioning

Site-Selective Ligand Selection by Mutational Profiling for Covalent RNA Targeting

Low butyrate concentrations exert anti-inflammatory and high concentrations exert pro-inflammatory effects on macrophages

Nucleotide dependency analysis of genomic language models detects functional elements

RNA dynamics from experimental and computational approaches

RNA structure probing, dynamics, and folding

Pers/media

Researchers Highlights How RNA Shape Changes Drive Drug Function

Binding to RNA is not enough—changing its shape is what makes a drug work, study reveals

Binding to RNA is not enough—changing its shape is what makes a drug work, study reveals

Why Most RNA-Targeting Drugs Fail

Gericht zoeken naar geneesmiddelen die structuur en functie van RNA beïnvloeden

Study shows how to identify drugs altering RNA structure and function

Study maps RNA shape-shifting mechanisms in human and bacterial cells

RNA Structural Switches Discovered in Humans and Bacteria

L'étude cartographie les mécanismes de changement de forme d'ARN dans les cellules humaines et bactériennes

Sustainable Development Goals

SDG 3 – Goede gezondheid en welzijnSDG 13 – Klimaatactie

Meer informatie over de Sustainable Development Goals.