dr. D.C.J. Spierings

d.c.j.spierings umcg.nl


Research interests

Single cell sequencing, genome instability, structural variations, ageing, stem cells, cancer, immunology

  1. A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

    Nelson, L., Tighe, A., Golder, A., Littler, S., Bakker, B., Moralli, D., Murtuza Baker, S., Donaldson, I. J., Spierings, D. C. J., Wardenaar, R., Neale, B., Burghel, G. J., Winter-Roach, B., Edmondson, R., Clamp, A. R., Jayson, G. C., Desai, S., Green, C. M., Hayes, A., Foijer, F., Morgan, R. D. & Taylor, S. S., 13-Feb-2020, In : Nature Communications. 11, 1, p. 822 18 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition

    Schukken, K. M., Lin, Y-C., Bakker, P. L., Schubert, M., Preuss, S. F., Simon, J. E., van den Bos, H., Storchova, Z., Colomé-Tatché, M., Bastians, H., Spierings, D. C. & Foijer, F., Feb-2020, In : Life science alliance. 3, 2, 15 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

    Sladky, V. C., Knapp, K., Soratroi, C., Heppke, J., Eichin, F., Rocamora-Reverte, L., Szabo, T. G., Bongiovanni, L., Westendorp, B., Moreno, E., van Liere, E. A., Bakker, B., Spierings, D. C. J., Wardenaar, R., Pereyra, D., Starlinger, P., Schultze, S., Trauner, M., Stojakovic, T., Scharnagl, H., Fava, L. L., Foijer, F., de Bruin, A. & Villunger, A., 13-Jan-2020, In : Developmental Cell.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Release of circulating tumor cells during surgery for non-small cell lung cancer: are they what they appear to be?

    Tamminga, M., de Wit, S., Van De Wauwer, C., van den Bos, H., Swennenhuis, J. F., Klinkenberg, T. J., Hiltermann, T. J. N., Andree, K. C., Spierings, D. C. J., Lansdorp, P. M., van den Berg, A., Timens, W., Terstappen, L. W. & Groen, H. J., 26-Nov-2019, In : Clinical Cancer Research. 31 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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  1. Data: Direct chromosome-length haplotyping by single-cell sequencing

    Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator), Guryev, V. (Creator), University of Groningen, 26-Nov-2016


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  1. Dutch Hematology congress

    Diana Spierings (Speaker)

    Activity: Talk or presentationAcademic

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  1. UMCG Innovation Prize for Research

    Diana Spierings (Recipient), 8-Jan-2019


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