dr. D.C.J. Spierings

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E-mail:
d.c.j.spierings umcg.nl

Research

Research interests

Single cell sequencing, genome instability, structural variations, ageing, stem cells, cancer, immunology

Publications
  1. Loss of NF2 defines a genetic subgroup of non-FOS-rearranged osteoblastoma

    Saba, K. H., Cornmark, L., Hofvander, J., Magnusson, L., Nilsson, J., van den Bos, H., Spierings, D. C., Foijer, F., Staaf, J., Brosjö, O., Sumathi, V. P., Lam, S. W., Szuhai, K., Bovée, J. V., Kovac, M., Baumhoer, D., Styring, E. & Nord, K. H., 16-Jun-2020, In : Journal of pathology clinical research. 7 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Transcriptional Activity and Stability of CD39+CD103+CD8+T Cells in Human High-Grade Endometrial Cancer

    Workel, H. H., van Rooij, N., Plat, A., Spierings, D. C. J., Fehrmann, R. S. N., Nijman, H. W. & de Bruyn, M., Jun-2020, In : International Journal of Molecular Sciences. 21, 11, 18 p., 3770.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Sperm DNA damage causes genomic instability in early embryonic development

    Middelkamp, S., van Tol, H. T. A., Spierings, D. C. J., Boymans, S., Guryev, V., Roelen, B. A. J., Lansdorp, P. M., Cuppen, E. & Kuijk, E. W., 15-Apr-2020, In : Science Advances. 6, 16, 12 p., eaaz7602.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Detection of Circulating Tumor Cells in the Diagnostic Leukapheresis Product of Non-Small-Cell Lung Cancer Patients Comparing CellSearch® and ISET

    Tamminga, M., Andree, K. C., Hiltermann, T. J. N., Jayat, M., Schuuring, E., van den Bos, H., Spierings, D. C. J., Lansdorp, P. M., Timens, W., Terstappen, L. W. M. M. & Groen, H. J. M., 7-Apr-2020, In : Cancers. 12, 4, 15 p., 896.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. The effects of common structural variants on 3D chromatin structure

    HGSVC, Shanta, O., Noor, A. & Sebat, J., 30-Jan-2020, In : BMC Genomics. 21, 1, 10 p., 95.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (49) »

Datasets
  1. Data: Direct chromosome-length haplotyping by single-cell sequencing

    Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator), Guryev, V. (Creator), University of Groningen, 26-Nov-2016

    Dataset

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Activities
  1. Dutch Hematology congress

    Diana Spierings (Speaker)
    24-Jan-201826-Jan-2018

    Activity: Talk or presentationAcademic

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Prizes
  1. UMCG Innovation Prize for Research

    Diana Spierings (Recipient), 8-Jan-2019

    PrizeAcademic

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ID: 176259