dr. D.C.J. Spierings

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E-mail:
d.c.j.spierings umcg.nl

Research

Research interests

Single cell sequencing, genome instability, structural variations, ageing, stem cells, cancer, immunology

Publications
  1. PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

    Sladky, V. C., Knapp, K., Szabo, T. G., Braun, V. Z., Bongiovanni, L., van den Bos, H., Spierings, D. C. J., Westendorp, B., Curinha, A., Stojakovic, T., Scharnagl, H., Timelthaler, G., Tsuchia, K., Pinter, M., Semmler, G., Foijer, F., de Bruin, A., Reiberger, T., Rohr-Udilova, N. & Villunger, A., 3-Dec-2020, In : Embo Reports. 21, 12, 16 p., 50893.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

    Sladky, V. C., Knapp, K., Szabo, T. G., Braun, V. Z., Bongiovanni, L., van den Bos, H., Spierings, D. C., Westendorp, B., Curinha, A., Stojakovic, T., Scharnagl, H., Timelthaler, G., Tsuchia, K., Pinter, M., Semmler, G., Foijer, F., de Bruin, A., Reiberger, T., Rohr-Udilova, N. & Villunger, A., 23-Nov-2020, In : Embo Reports. 21, 12, 16 p., 50893.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway

    Phan, T. P., Maryniak, A. L., Boatwright, C. A., Lee, J., Atkins, A., Tijhuis, A., Spierings, D. C., Bazzi, H., Foijer, F., Jordan, P. W., Stracker, T. H. & Holland, A. J., 23-Nov-2020, In : The EMBO Journal. 1, 18 p., 106118.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. IL-1 beta Induces a Pro-Inflammatory Fibroblast Micro-Environment That Impairs Alveolar Epithelial Organoid Formation

    Ciminieri, C., Woest, M., Reynaert, N. L., Heijink, I. H., Wardenaar, R., Spierings, D. C. J., Brandsma, C. A., Koenigshoff, M. & Gosens, R., 2020, In : American Journal of Respiratory and Critical Care Medicine. 201, 2 p.

    Research output: Contribution to journalMeeting AbstractAcademic

  5. Loss of NF2 defines a genetic subgroup of non-FOS-rearranged osteoblastoma

    Saba, K. H., Cornmark, L., Hofvander, J., Magnusson, L., Nilsson, J., van den Bos, H., Spierings, D. C., Foijer, F., Staaf, J., Brosjö, O., Sumathi, V. P., Lam, S. W., Szuhai, K., Bovée, J. V., Kovac, M., Baumhoer, D., Styring, E. & Nord, K. H., 16-Jun-2020, In : Journal of pathology clinical research. 6, 4, p. 231-237 7 p.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (54) »

Datasets
  1. Data: Direct chromosome-length haplotyping by single-cell sequencing

    Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator) & Guryev, V. (Creator), University of Groningen, 26-Nov-2016

    Dataset

View all (1) »

Activities
  1. Dutch Hematology congress

    Diana Spierings (Speaker)

    24-Jan-201826-Jan-2018

    Activity: Talk or presentationAcademic

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Prizes
  1. UMCG Innovation Prize for Research

    Spierings, Diana (Recipient), 8-Jan-2019

    PrizeAcademic

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ID: 176259