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Practical matters How to find us dr. C.A. (Corry-Anke) Brandsma

Research interests

Corry-Anke Brandsma, born in Leeuwarden in 1980, completed her master in Medical Biology at the RUG, Groningen in 2003. She was appointed as a PhD student from 2003-2007 on a joined project of the departments of Pathology and Pulmonary diseases of the UMCG on the inflammatory response in COPD. From 2007-2014 she worked as a post-doc on several research projects funded by the Dutch Lung Foundation. In 2011 she received international research fellowships from the European Respiratory Society and the Dutch Lung Foundation to work in the lab of Prof. J.C. Hogg in Vancouver (Canada). In 2014 she was appointed as staff member by the department of Pathology of the UMCG.

During her first post-doc, she focused on the role of adaptive immunity and B lymphocytes in COPD and demonstrated the presence of a smoke-induced specific immune response, which differed between COPD patients and healthy controls. After that, she steered her research focus to the role of accelerated lung aging and abnormal tissue repair in COPD, which is currently her main research focus. Using primary lung cells and lung tissue from well-characterized COPD patients and non-COPD control subjects she tries to unravel the molecular mechanisms underlying accelerated lung aging and abnormal tissue repair in COPD. For this, she uses a “multi-omics” approach combining information on changes in the genome (DNA), transcriptome (RNA, miRNA) and the proteome (protein) to identify causal molecular networks in COPD.  

Publications

Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways

Differential roles for lysyl oxidase (like), family members in chronic obstructive pulmonary disease: from gene and protein expression to function

High miR203a-3p and miR-375 expression in the airways of smokers with and without COPD

Identification of asthma associated microRNAs in bronchial biopsies

MicroRNAs Associated with Chronic Mucus Hypersecretion in COPD Are Involved in Fibroblast-Epithelium Crosstalk

The Microbiome in Bronchial Biopsies from Smokers and Ex-Smokers with Stable COPD - A Metatranscriptomic Approach

The relation between age and airway epithelial barrier function

A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract

Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic mechanisms

BET proteins are associated with the induction of small airway fibrosis in COPD

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Press/media

Is COPD een verzamelnaam voor verschillende ziekten?

Interview Longwijzer