prof. dr. B.J.L. (Bart) Eggen

Professor

Faculteit Medische Wetenschappen/UMCG

Telefoon:

E-mail:

b.j.l.eggen umcg.nl

Homepage ORCID Research Portal

Publicaties

Calorie restriction increases the sensitivity of progeroid Ercc1Δ/− mice to acute (neuro)inflammation

Reitsema, V. A., Schreuder, L., Gerrits, E., Eggen, B. J. L., Goris, M., Laman, J. D., de Rooij, S. E., Wesseling, E. M., Bouma, H. R. & Henning, R. H., apr.-2025, In: GeroScience. 47, blz. 1641–1652 12 blz.

Onderzoeksoutput: Article › › peer review

Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

Matera, A., Compagnion, A. C., Pedicone, C., Kotah, J. M., Ivanov, A., Monsorno, K., Labouèbe, G., Leggio, L., Pereira-Iglesias, M., Beule, D., Mansuy-Aubert, V., Williams, T. L., Iraci, N., Sierra, A., Marro, S. G., Goate, A. M., Eggen, B. J. L., Kerr, W. G. & Paolicelli, R. C., 14-jan.-2025, In: Immunity. 58, 1, blz. 197-217.e13 35 blz.

Onderzoeksoutput: Editorial › › peer review

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5

Montilla, A., Zabala, A., Calvo, I., Bosch-Juan, M., Tomé-Velasco, I., Mata, P., Koster, M., Sierra, A., Kooistra, S. M., Soria, F. N., Eggen, B. J. L., Fresnedo, O., Fernández, J. A., Tepavcevic, V., Matute, C. & Domercq, M., 25-mrt.-2025, In: Cellular and molecular life sciences. 82, 21 blz., 131.

Onderzoeksoutput: Article › › peer review

Unboxing “Omics” in Glial Biology to Understand Neurological Disease

Weinstein, J. R., Jayadev, S., Liddelow, S. & Eggen, B. J. L., mrt.-2025, In: Glia. 73, 3, blz. 448-450 3 blz.

Onderzoeksoutput: Editorial › › peer review

WDR49-Positive Astrocytes Mark Severity of Neurodegeneration in Frontotemporal Lobar Degeneration and Alzheimer's Disease

Rajicic, A., Giannini, L. A. A., Gerrits, E., van Buuren, R., Melhem, S., Slotman, J. A., Rozemuller, A. J. M., Eggen, B. J. L., van Swieten, J. C. & Seelaar, H., 2025, In: Glia. 73, 5, blz. 948-968 21 blz.

Onderzoeksoutput: Article › › peer review

An anti-aging vaccine: BCG turns back the clock on remyelination failure

Kotah, J. M. & Eggen, B. J. L., 10-sep.-2024, In: Immunity. 57, 9, blz. 2005-2007 3 blz.

Onderzoeksoutput › › peer review

ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome

Kuil, L. E., Chauhan, R. K., de Graaf, B. M., Cheng, W. W., Kakiailatu, N. J. M., Lasabuda, R., Verhaeghe, C., Windster, J. D., Schriemer, D., Azmani, Z., Brooks, A. S., Edie, S., Reeves, R. H., Eggen, B. J. L., Shepherd, I. T., Burns, A. J., Hofstra, R. M. W., Melotte, V., Brosens, E. & Alves, M. M., mrt.-2024, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1870, 3, 10 blz., 166991.

Onderzoeksoutput: Article › › peer review

Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours

Sabogal-Guaqueta, A. M., Mitchell-Garcia, T., Hunneman, J., Voshart, D., Thiruvalluvan, A., Foijer, F., Kruyt, F., Trombetta-Lima, M., Eggen, B. J. L., Boddeke, E., Barazzuol, L. & Dolga, A. M., dec.-2024, In: Neurobiology of Disease. 203, 16 blz., 106742.

Onderzoeksoutput: Review article › peer review

Cellular senescence in brain aging and neurodegeneration

Melo Dos Santos, L. S., Trombetta-Lima, M., Eggen, B. & Demaria, M., jan.-2024, In: Ageing Research Reviews. 93, 12 blz., 102141.

Onderzoeksoutput: Review article › peer review

Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice

Oshima, T., Kater, M. S. J., Huffels, C. F. M., Wesseling, E. M., Middeldorp, J., Hol, E. M., Verheijen, M. H. G., Smit, A. B., Boddeke, E. W. G. M. & Eggen, B. J. L., mrt.-2024, In: Journal of Neuroscience Research. 102, 3, 14 blz., e25295.

Onderzoeksoutput: Article › › peer review