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Publicaties

Benchmarking scRNA-seq copy number variation callers

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis

Single-cell chromosome and bulk transcriptome analysis as a diagnostic tool to differentiate between localized and metastatic pheochromocytoma and sympathetic paraganglioma

Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy

Characterizing chromosomal instability-driven cancer evolution and cell fitness at a glance

Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy

Extra centrosomes delay DNA damage-driven tumorigenesis

Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization

Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition

Short-term molecular consequences of chromosome mis-segregation for genome stability