dr. A.R. (Arno) Bourgonje
MD, PhD, Postdoctoral researcher
E-mail:
a.r.bourgonje umcg.nl
Field/Discipline
Expertise
My research is focused on the discovery and application of novel biomarker signatures in patients with inflammatory bowel diseases (IBD), while also assessing their potential for therapeutic modulation (e.g., through dietary interventions) and their utility to predict clinical outcomes (e.g., response to established medical treatment). My strategy is to identify functionally relevant disease markers derived from different biological systems (e.g., the immune system, host genetics, the gut microbiome) and -mechanisms (e.g., inflammatory pathways, oxidative stress and redox signaling, iron metabolism and hypoxia) and carefully examine these signatures through detailed phenotypic patient stratification. By adopting this multi-faceted approach and studying the interplay between different pathophysiological entities, my ultimate aim is to develop and validate clinically applicable prediction models using evidence-based translational biomarkers.
"Adding patient value by data-driven personalized healthcare."
"Adding patient value by data-driven personalized healthcare."
| Last modified: | 05 April 2023 2.40 p.m. |