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About us Practical matters How to find us A. Plat, MSc

University Medical Center Groningen

A. Plat, MSc

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Faculty of Medical Sciences

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a.plat umcg.nl

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Publications

Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors

Ważyńska, M. A., Butera, R., Requesens, M., Plat, A., Zarganes-Tzitzikas, T., Neochoritis, C. G., Plewka, J., Skalniak, L., Kocik-Krol, J., Musielak, B., Magiera-Mularz, K., Rodriguez, I., Blok, S. N., de Bruyn, M., Nijman, H. W., Elsinga, P. H., Holak, T. A. & Dömling, A., 27-Jul-2023, In: Journal of Medicinal Chemistry. 66, 14, p. 9577-9591 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Development of 89 Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration

Kol, A., Fan, X., Wazynska, M. A., Van Duijnhoven, S. M. J., Giesen, D., Plat, A., Van Eenennaam, H., Elsinga, P. H., Nijman, H. W. & De Bruyn, M., 5-Dec-2022, In: Journal for immunotherapy of cancer. 10, 12, 32 p., e004877.

Research output: Contribution to journal › Article › Academic › peer-review

Expression of CD39 Identifies Activated Intratumoral CD8+T Cells in Mismatch Repair Deficient Endometrial Cancer

Lubbers, J. M., Ważyńska, M. A., van Rooij, N., Kol, A., Workel, H. H., Plat, A., Paijens, S. T., Vlaming, M. R., Spierings, D. C. J., Elsinga, P. H., Bremer, E., Nijman, H. W. & de Bruyn, M., 11-Apr-2022, In: Cancers. 14, 8, 13 p., 1924.

Research output: Contribution to journal › Article › Academic › peer-review

Tumor infiltrating CD8/CD103/TIM-3-expressing lymphocytes in epithelial ovarian cancer co-express CXCL13 and associate with improved survival

Vlaming, M., Bilemjian, V., Freile, J. Á., Melo, V., Plat, A., Huls, G., Nijman, HW., de Bruyn, M. & Bremer, E., 21-Oct-2022, In: Frontiers in Immunology. 13, 11 p., 1031746.

Research output: Contribution to journal › Article › Academic › peer-review

Association of homozygous variants of STING1 with outcome in human cervical cancer

Lubbers, J. M., Koopman, B., de Klerk-Sluis, J. M., van Rooij, N., Plat, A., Pijper, H., Koopman, T., van Hemel, B. M., Hollema, H., Wisman, B., Nijman, H. W. & de Bruyn, M., Jan-2021, In: Cancer science. 112, 1, p. 61-71 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Combined STING levels and CD103+ T cell infiltration have significant prognostic implications for patients with cervical cancer

Kol, A., Lubbers, J. M., Terwindt, A. L. J., Workel, H. H., Plat, A., Wisman, G. B. A., Bart, J., Nijman, H. W. & De Bruyn, M., 12-Jun-2021, In: OncoImmunology. 10, 1, 12 p., 1936391.

Research output: Contribution to journal › Article › Academic › peer-review

Prognostic image-based quantification of CD8CD103 T cell subsets in high-grade serous ovarian cancer patients

Paijens, S. T., Vledder, A., Loiero, D., Duiker, E. W., Bart, J., Hendriks, A. M., Jalving, M., Workel, H. H., Hollema, H., Werner, N., Plat, A., Wisman, G. B. A., Yigit, R., Arts, H., Kruse, A. J., de Lange, N. M., Koelzer, V. H., de Bruyn, M. & Nijman, H. W., 6-Jun-2021, In: OncoImmunology. 10, 1, 11 p., 1935104.

Research output: Contribution to journal › Article › Academic › peer-review

Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome

Merkus-Brunekreeft, K., Paijens, S., Wouters, M., Komdeur, F., Eggink, F., Lubbers-Marsman, J., Workel, H., Slikke, van der, E. C., Propper, N. E. J., Leffers, N., Adam, J., Pijper, H., Plat, A., Kol, A., Nijman, H. & Bruyn, de, M., 13-May-2020, In: OncoImmunology. 9, 1, p. 1-12 12 p., 1760705.

Research output: Contribution to journal › Article › Academic › peer-review

Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer

Horeweg, N., de Bruyn, M., Nout, R. A., Stelloo, E., Kedzierska, K. Z., León-Castillo, A., Plat, A., Mertz, K. D., Osse, M., Jürgenliemk-Schulz, I. M., Lutgens, L. C., Jobsen, J. J., van der Steen-Banasik, E. M., Smit, V. T. H. B. M., Creutzberg, C. L., Bosse, T., Nijman, H. W., Koelzer, V. H. & Church, D. N., 1-Dec-2020, In: Cancer immunology research. 8, 12, p. 1508-1519 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Transcriptional Activity and Stability of CD39+CD103+CD8+T Cells in Human High-Grade Endometrial Cancer

Workel, H. H., van Rooij, N., Plat, A., Spierings, D. C. J., Fehrmann, R. S. N., Nijman, H. W. & de Bruyn, M., Jun-2020, In: International Journal of Molecular Sciences. 21, 11, 18 p., 3770.

Research output: Contribution to journal › Article › Academic › peer-review

All (24) publications

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