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Practical matters How to find us dr. A.M.W.H. (Andy-Mark) Thunnissen

Publications

Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C‐C Bond‐Forming Enzyme

Biocatalytic Enantioselective Hydroaminations Enabling Synthesis of N-Arylalkyl-Substituted L-Aspartic Acids

Computational Redesign of an ω-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines

Unlocking Asymmetric Michael Additions in an Archetypical Class I Aldolase by Directed Evolution

Using Mutability Landscapes To Guide Enzyme Thermostabilization

Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme

Engineered C–N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners Catalyzed by an Engineered C-N Lyase

Robust ω-Transaminases by Computational Stabilization of the Subunit Interface

Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

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Press/media

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