Skip to Content Skip to Navigation

Practical matters How to find us dr. A.M.W.H. (Andy-Mark) Thunnissen

dr. A.M.W.H. (Andy-Mark) Thunnissen

Assistant Professor

Profielfoto van dr. A.M.W.H. (Andy-Mark) Thunnissen

No picture available

Faculty of Science and Engineering

Telephone:

+31 50 36 34380

E-mail:

a.m.w.h.thunnissen rug.nl

Homepage ORCID Research Portal

Publications

Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C‐C Bond‐Forming Enzyme

Xu, G. , Kunzendorf, A. , Crotti, M. , Rozeboom, H. J. , Thunnissen, A. W. H. & Poelarends, G. J. , 14-Feb-2022 , In: Angewandte Chemie International Edition. 61 , 8 , 6 p. , e202113970.

Research output: Contribution to journal › Article › Academic › peer-review

The Role of Tryptophan in π Interactions in Proteins: An Experimental Approach

Shao, J. , Kuiper, B. P. , Thunnissen, A-M. W. H. , Cool, R. H. , Zhou, L. , Huang, C. , Dijkstra, B. W. & Broos, J. , Sept-2022 , In: Journal of the American Chemical Society. 144 , 30 , p. 13815-13822 8 p. , 04986.

Research output: Contribution to journal › Article › Academic › peer-review

Biocatalytic Enantioselective Hydroaminations Enabling Synthesis of N-Arylalkyl-Substituted L-Aspartic Acids

Abidin, M. M. , Thangavelu, S. , Bothof, L. , Tepper, P. , Thunnissen, A. & Poelarends, G. J. , Aug-2021 , In: Organic & Biomolecular Chemistry. 19 , 29 , p. 6407–6411 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Computational Redesign of an ω-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines

Meng, Q. , Ramírez-Palacios, C. , Capra, N. , Hooghwinkel, M. E. , Thallmair, S. , Rozeboom, H. J. , Thunnissen, A. M. W. H. , Wijma, H. J. , Marrink, S. J. & Janssen, D. B. , Aug-2021 , In: ACS Catalysis. 11 , 17 , p. 10733-10747 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Unlocking Asymmetric Michael Additions in an Archetypical Class I Aldolase by Directed Evolution

Kunzendorf, A. , Xu, G. , Van Der Velde, J. J. H. , Rozeboom, H. J. , Thunnissen, A. W. H. & Poelarends, G. J. , 5-Nov-2021 , In: ACS Catalysis. 11 , 21 , p. 13236-13243 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Using Mutability Landscapes To Guide Enzyme Thermostabilization

Guo, C. , Ni, Y. , Biewenga, L. , Pijning, T. , Thunnissen, A-M. W. H. & Poelarends, G. J. , 5-Jan-2021 , In: ChemBioChem. 22 , 1 , p. 170-175 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme

Villarino, L. , Chordia, S. , Alonso-Cotchico, L. , Reddem, E. , Zhou, Z. , Thunnissen, A. M. W. H. , Maréchal, J-D. & Roelfes, G. , 18-Sept-2020 , In: ACS Catalysis. 10 , 20 , p. 11783-11790 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Engineered C–N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners Catalyzed by an Engineered C-N Lyase

Zhang, J. , Grandi, E. , Fu, H. , Thangavelu, S. , Bothof, L. , Tepper, P. G. , Thunnissen, A-M. W. H. & Poelarends, G. J. , 2-Jan-2020 , In: Angewandte Chemie International Edition. 59 , 1 , p. 429-435 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Robust ω-Transaminases by Computational Stabilization of the Subunit Interface

Meng, Q. , Capra, N. , Palacio, C. M. , Lanfranchi, E. , Otzen, M. , Van Schie, L. Z. , Rozeboom, H. J. , Thunnissen, A. M. W. H. , Wijma, H. J. & Janssen, D. B. , 6-Mar-2020 , In: ACS Catalysis. 10 , 5 , p. 2915-2928 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid

Mayer, C. , Dulson, C. , Reddem, E. , Thunnissen, A-M. W. H. & Roelfes, G. , 11-Feb-2019 , In: Angewandte Chemie-International Edition. 58 , 7 , p. 2083-2087 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (68) publications

Press/media

Kunstmatige intelligentie kraakt een van de grote raadsels in de biologie

Andy Thunnissen

16/09/2022

Press/Media: Expert Comment › Popular

3D ontdekkingstocht in de wereld van eiwitten

Andy Thunnissen

14/01/2017

Press/Media: Other › Popular

All (2) press/media

View full research profile

Follow the UGfacebook twitter linkedin rss instagram youtube