prof. dr. A.J. (Tineke) Oldehinkel
Professor Lifecourse Epidemiology of Common Mental Disorders
Research
Research interests
I am a professor of Lifecourse Epidemiology of Common Mental Disorders. Being trained as an (experimental) psychologist, (bio)statistician and epidemiologist, I have always worked on the crossroads of medical and social sciences. My affinity with multi- and interdisciplinary research is reflected in my leadership of the Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), which performs research at the junction of various disciplines, with the aim to unravel psychobiological processes involved in the onset and course of common mental problems, in particular affective disorders. In addition, I am principal investigator of the longitudinal study TRAILS (Tracking Adolescents’ Individual Lives Survey, www.trails.nl), which was set up over fourteen years ago to chart and explain the mental health and development of adolescents and young adults, and involves researchers working in various scientific domains and institutes in the Netherlands and abroad.
My inspiration as a scientist is driven by a great deal of curiosity as well as the desire to better understand and predict the intricacies of the onset of course of mental health problems in order to improve prevention and care. My research mainly focuses on the interplay of individual psychobiological vulnerability and resilience factors, conceived as the result of genetic endowment and past experiences, and environmental challenges in the development and course of depressive symptoms. This work is based on observational data collected in large longitudinal epidemiological surveys, complemented with studies involving many repeated measurements in smaller groups to assess temporal patterns of specific mood-related factors and the effects of interventions thereon. An example of such a study concerns the question how adolescents lose the ability to experience pleasure and may gain it back again (www.nofunnoglory.nl).
Publications
Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (vol 21, pg 1161, 2018)
23andMe Res Team, Psychiat Genomics Consortium Int & Int Cannabis Consortium, Jul-2019, In : Nature neuroscience. 22, 7, p. 1196 1 p.Research output: Contribution to journal › Article › Academic › peer-review
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Lifelines Cohort Study, Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M., Ghasemi, S., Xu, Y., Horn, K., Noce, D., Van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Arnlov, J., Bakker, S. J. L., Bansal, N., De Borst, M. H., De Vries, A. P. J., Demirkan, A., Gansevoort, R. T., Hartman, C. A., Huang, W., Nolte, I. M., Oldehinkel, A. J., Penninx, B. W. J. H., Prins, B. P., Smith, A. V., Van der Harst, P., Verweij, N., Wang, Y. X., Xu, L., Snieder, H. & Thio, C. H. L., Jun-2019, In : Nature Genetics. 51, 6, p. 957-+ 19 p.Research output: Contribution to journal › Article › Academic › peer-review
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Lifelines Cohort Study, 10-Apr-2019, In : Human Molecular Genetics. 19 p.Research output: Contribution to journal › Article › Academic › peer-review
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
COGENT-Kidney Consortium, EPIC-InterAct Consortium, Understanding Soc Sci Grp & Lifelines Cohort, Apr-2019, In : Nature Genetics. 51, 4, p. 636-+ 16 p.Research output: Contribution to journal › Article › Academic › peer-review
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects
EAGLE Consortium, EGG Consortium, EGG Membership & EAGLE Membership, Mar-2019, In : European Journal of Epidemiology. 34, 3, p. 279-300 22 p.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
Replication data to: Cortisol and α-amylase secretion patterns between and within depressed and non-depressed individuals.
Booij, S. (Creator), Bos, E. (Creator), Bouwmans, M. (Creator), Kema, I. (Creator), University of Groningen, 6-Jul-2015
DOI: https://doi.org/10411/C8LWAC, https://doi.org/10.1371/journal.pone.0131002.s013
Dataset
Dataset: Self-monitoring and personalized feedback as a tool to boost depression treatment: ZELF-i
Bastiaansen, J. (Creator), Meurs, M. (Creator), Stelwagen, R. (Creator), Wunderink, L. (Creator), Schoevers, R. (Creator), Wichers, M. (Creator), Oldehinkel, T. (Creator), University of Groningen, 2019
Dataset
Tracking Adolescents' Individual Lives Survey ( TRAILS ) T5 Population Cohort
Oldehinkel, T. (Creator), Verhulst, F. (Creator), University of Groningen, 1-Sep-2015
DOI: https://doi.org/10.17026/dans-2aa-wj84, http://www.trails.nl/ and one more link, http://www.trails.nl/topmenu/contact (show fewer)
Dataset
Prizes
Top nominee (2nd place) best supervisor of the year award
Tineke Oldehinkel (Recipient), 2015
Prize › Academic
Activities
Graduate School Medical Sciences - General (Organisational unit)
Tineke Oldehinkel (Member)2018 → …Activity: Membership › Membership of committee › Academic
Waarom worden jonge mensen depressief?
Tineke Oldehinkel (Speaker)27-Mar-2018Activity: Talk or presentation › Professional
Development MOOC 'Young people and their mental health'
Tineke Oldehinkel (Other), Maaike Meurs (Other), Tom Spits (Other)Feb-2017 → Jan-2018Activity: Other › Popular
Press / Media
Jong en depressief. Hoe vind je de weg terug als je op de bodem zit?
13/07/2019
1 media contribution
Press/Media: Expert Comment › Popular
Depressie bij jongeren
Tineke Oldehinkel & Robert Schoevers
24/03/2018 → 26/03/2018
2 media contributions
Press/Media: Expert Comment › Popular
Free online course about mental health for young people
Tineke Oldehinkel & Maaike Meurs
11/01/2018
1 media contribution
Press/Media: Public Engagement Activities › Popular
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