prof. dr. A.J. (Tineke) Oldehinkel

Hoogleraar Levensloop Epidemiologie van Veelvoorkomende Psychiatrische Stoornissen

Research

Research interests

I am a professor of Lifecourse Epidemiology of Common Mental Disorders. Being trained as an (experimental) psychologist, (bio)statistician and epidemiologist, I have always worked on the crossroads of medical and social sciences. My affinity with multi- and interdisciplinary research is reflected in my leadership of the Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), which performs research at the junction of various disciplines, with the aim to unravel psychobiological processes involved in the onset and course of common mental problems, in particular affective disorders. In addition, I am principal investigator of the longitudinal study TRAILS (Tracking Adolescents’ Individual Lives Survey, www.trails.nl), which was set up over fourteen years ago to chart and explain the mental health and development of adolescents and young adults, and involves researchers working in various scientific domains and institutes in the Netherlands and abroad.

My inspiration as a scientist is driven by a great deal of curiosity as well as the desire to better understand and predict the intricacies of the onset of course of mental health problems in order to improve prevention and care. My research mainly focuses on the interplay of individual psychobiological vulnerability and resilience factors, conceived as the result of genetic endowment and past experiences, and environmental challenges in the development and course of depressive symptoms. This work is based on observational data collected in large longitudinal epidemiological surveys, complemented with studies involving many repeated measurements in smaller groups to assess temporal patterns of specific mood-related factors and the effects of interventions thereon. An example of such a study concerns the question how adolescents lose the ability to experience pleasure and may gain it back again (www.nofunnoglory.nl).

Publications
  1. Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D., Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Peyrot, W. J., Wu, Y., Kristiansson, K., Demirkan, A., Fornage, M., Hassinen, M., Bielak, L. F., Cadby, G., Tanaka, T., Mägi, R., van der Most, P. J., Jackson, A. U., Bragg-Gresham, J. L., Vitart, V., Marten, J., Navarro, P., Bellis, C., Pasko, D., Johansson, Å., Snitker, S., Cheng, Y-C., Eriksson, J., Lim, U., Aadahl, M., Adair, L. S., Amin, N., Balkau, B., Auvinen, J., Beilby, J., Bergman, R. N., Bergmann, S., Bertoni, A. G., Blangero, J., Bonnefond, A., Bonnycastle, L. L., Borja, J. B., Brage, S., Busonero, F., Buyske, S., Campbell, H., Chines, P. S., Collins, F. S., Corre, T., Smith, G. D., Delgado, G. E., Dueker, N., Dörr, M., Ebeling, T., Eiriksdottir, G., Esko, T., Faul, J. D., Fu, M., Færch, K., Gieger, C., Gläser, S., Gong, J., Gordon-Larsen, P., Grallert, H., Grammer, T. B., Grarup, N., van Grootheest, G., Harald, K., Hastie, N. D., Havulinna, A. S., Hernandez, D., Hindorff, L., Hocking, L. J., Holmens, O. L., Holzapfel, C., Hottenga, J. J., Huang, J., Huang, T., Hui, J., Huth, C., Hutri-Kähönen, N., James, A. L., Jansson, J-O., Jhun, M. A., Juonala, M., Kinnunen, L., Koistinen, H. A., Kolcic, I., Komulainen, P., Kuusisto, J., Kvaløy, K., Kähönen, M., Lakka, T. A., Launer, L. J., Lehne, B., Lindgren, C. M., Lorentzon, M., Luben, R., Marre, M., Milaneschi, Y., Monda, K. L., Montgomery, G. W., De Moor, M. H. M., Mulas, A., Müller-Nurasyid, M., Musk, A. W., Männikkö, R., Männistö, S., Narisu, N., Nauck, M., Nettleton, J. A., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Paternoster, L., Perez, J., Perola, M., Peters, A., Peters, U., Peyser, P. A., Prokopenko, I., Puolijoki, H., Raitakari, O. T., Rankinen, T., Rasmussen-Torvik, L. J., Rawal, R., Ridker, P. M., Rose, L. M., Rudan, I., Sarti, C., Sarzynski, M. A., Savonen, K., Scott, W. R., Sanna, S., Shuldiner, A. R., Sidney, S., Silbernagel, G., Smith, B. H., Smith, J. A., Snieder, H., Stančáková, A., Sternfeld, B., Swift, A. J., Tammelin, T., Tan, S-T., Thorand, B., Thuillier, D., Vandenput, L., Vestergaard, H., van Vliet-Ostaptchouk, J. V., Vohl, M-C., Völker, U., Waeber, G., Walker, M., Wild, S., Wong, A., Wright, A. F., Zillikens, M. C., Zubair, N., Haiman, C. A., Lemarchand, L., Gyllensten, U., Ohlsson, C., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Pérusse, L., Wilson, J. F., Hayward, C., Polasek, O., Cucca, F., Hveem, K., Hartman, C. A., Tönjes, A., Bandinelli, S., Palmer, L. J., Kardia, S. L. R., Rauramaa, R., Sørensen, T. I. A., Tuomilehto, J., Salomaa, V., Penninx, B. W. J. H., de Geus, E. J. C., Boomsma, D. I., Lehtimäki, T., Mangino, M., Laakso, M., Bouchard, C., Martin, N. G., Kuh, D., Liu, Y., Linneberg, A., März, W., Strauch, K., Kivimäki, M., Harris, T. B., Gudnason, V., Völzke, H., Qi, L., Järvelin, M-R., Chambers, J. C., Kooner, J. S., Froguel, P., Kooperberg, C., Vollenweider, P., Hallmans, G., Hansen, T., Pedersen, O., Metspalu, A., Wareham, N. J., Langenberg, C., Weir, D. R., Porteous, D. J., Boerwinkle, E., Chasman, D. I., Abecasis, G. R., Barroso, I., McCarthy, M. I., Frayling, T. M., O'Connell, J. R., van Duijn, C. M., Boehnke, M., Heid, I. M., Mohlke, K. L., Strachan, D. P., Fox, C. S., Liu, C-T., Hirschhorn, J. N., Klein, R. J., Johnson, A. D., Borecki, I. B., Franks, P. W., North, K. E., Cupples, L. A., Loos, R. J. F., Kilpeläinen, T. O. & CHARGE Consortium Aug-2017 In : PLoS genetics. 13, 8, p. e1006972

    Research output: Scientific - peer-reviewArticle

  2. Editorial: Let's talk about sex - the gender binary revisited

    Oldehinkel, A. J. Aug-2017 In : Journal of Child Psychology and Psychiatry. 58, 8, p. 863-864 2 p.

    Research output: Scientific - peer-reviewEditorial

  3. Reward and punishment learning in daily life: A replication study

    Heininga, V. E., van Roekel, E., Wichers, M. & Oldehinkel, A. J. 4-Oct-2017 In : Plos one. 12, 10, 18 p., 0180753

    Research output: Scientific - peer-reviewArticle

  4. Let’s talk about sex – The gender binary revisited.

    Oldehinkel, A. Aug-2017 In : Journal of Child Psychology and Psychiatry. 58, 8, p. 863-864 2 p.

    Research output: Scientific - peer-reviewEditorial

  5. CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

    Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C., van der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M-L., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, T., Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z. 29-Sep-2017 In : Nature Communications. 8, 1, 11 p., 744

    Research output: Scientific - peer-reviewArticle

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Activities
  1. NWO (External organisation)

    Oldehinkel, T. (Member)
    2017 → …

    Activity: ScientificMembership of committee

  2. Dutch Brain Foundation (External organisation)

    Oldehinkel, T. (Member)
    20102013

    Activity: ScientificMembership of committee

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Press / Media
  1. Prestatiedruk drijft jongeren tot wanhoop

    Tineke Oldehinkel

    02/05/2017

    1 item of media coverage

    Press / Media: Expert Comment

  2. Plezier van parachutesprong duurt maar kort

    Tineke Oldehinkel

    30/11/2016

    1 item of media coverage

    Press / Media: Research

  3. Leefstijladviezen brengen plezier terug

    Tineke Oldehinkel

    19/11/2016

    1 item of media coverage

    Press / Media: Research

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