dr. A. (Albert) Guskov

Assistant Professor / Group leader (NWO Vidi Fellow)

dr. A. (Albert) Guskov
E-mail:
a.guskov rug.nl

Research

Research units:

Postal address:
Nijenborgh
7
Gebouw 5171
Groningen
Netherlands
Phone: +31 50 363 4391Fax: +31 50 363 4381
Publications
  1. Binding and transport of D-aspartate by the glutamate transporter homologue GltTk

    Arkhipova, V. I., Trinco, G., Thijs, E., Jensen, S., Slotboom, D. & Guskov, A., 1-May-2019, In : eLife. 8, e45286.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β-mannan possess distinct manno-oligosaccharide binding profiles

    Ejby, M., Guskov, A., Pichler, M. J., Zanten, G. C., Schoof, E., Saburi, W., Slotboom, D. J. & Abou Hachem, M., Jul-2019, In : Molecular Microbiology. 112, 1, p. 114-130 14257.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM

    Rempel, S., Colucci, E., Gier, J-W. D., Guskov, A. & Slotboom, D., 2-Aug-2018, In : Nature Communications. 9, 1, 8 p., 3038.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Cryo-EM structure of the human neutral amino acid transporter ASCT2

    Garaeva, A., Oostergetel, G., Gati, C., Guskov, A., Batista Paulino, C. & Slotboom, D., 5-Jun-2018, In : Nature Structural & Molecular Biology. 25, p. 515-521

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Functional and structural characterization of an ECF-type ABC transporter for vitamin B12

    Luís da Silva Santos Guimarães, J. A., Rempel, S., Mous, S. T. M., Tambascia Pereira, C., ter Beek, J., Gier, J-W. D., Guskov, A. & Slotboom, D., 2018, In : eLife. 7, 16 p., e35828.

    Research output: Contribution to journalArticleAcademicpeer-review

  6. The structural basis of proton driven zinc transport by ZntB

    Gati, C., Stetsenko, A., Slotboom, D., Scheres, S. & Guskov, A., 3-Nov-2017, In : Nature Communications. 8, 8 p., 1313.

    Research output: Contribution to journalArticleAcademicpeer-review

  7. Analysis of the quality of crystallographic data and the limitations of structural models

    Arkhipova, V. I., Guskov, A. & Slotboom, D., Dec-2017, In : The Journal of General Physiology. 149, 12, 13 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  8. A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy

    Franken, L., Oostergetel, G., Pijning, T., Puri, P., Arkhipova, V. I., Boekema, E., Poolman, B. & Guskov, A., 28-Sep-2017, In : Nature Communications. 8, 11 p., 722.

    Research output: Contribution to journalArticleAcademicpeer-review

  9. An Overview of the Top Ten Detergents Used for Membrane Protein Crystallization

    Stetsenko, A. & Guskov, A., 1-Jul-2017, In : Crystals. 7, 7, p. 1-16 16 p., 197.

    Research output: Contribution to journalArticleAcademicpeer-review

  10. Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk

    Guskov, A., Jensen, S., Faustino, I., Marrink, S. J. & Slotboom, D. J., 2016, In : Nature Communications. 7, p. 1-6 6 p., 13420.

    Research output: Contribution to journalArticleAcademicpeer-review

  11. Size exclusion chromatography with multi-angle laser light scattering (SEC-MALLS) to determine protein oligomeric states

    Guskov, A. & Slotboom, D., Jan-2016, From molecules to living organisms: an interplay between biology and physics: Lecture Notes of the Les Houches School of Physics: Volume 102, July 2014. Pebay-Peyroula, E., Nury, H., Parcy, F., Ruigrok, R. W. H., Ziegler, C. & Cugliandolo, L. F. (eds.). Oxford University Press, p. 169-183 6. (Lecture Notes of the Les Houches School of Physics; vol. 102).

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

  12. Structural insight in the toppling mechanism of an energy-coupling factor transporter

    Swier, L. J. Y. M., Guskov, A. & Slotboom, D. J., 30-Mar-2016, In : Nature Communications. 7, p. 1-11 12 p., 11072.

    Research output: Contribution to journalArticleAcademicpeer-review

  13. Pnu Transporters: Ain't They SWEET?

    Jähme, M., Guskov, A. & Slotboom, D. J., Feb-2016, In : Trends in Biochemical Sciences. 41, 2, p. 117-118 2 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  14. The twisted relation between Pnu and SWEET transporters

    Jähme, M., Guskov, A. & Slotboom, D., 7-Mar-2015, In : Trends in Biochemical Sciences. 40, 4, p. 183-188 6 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  15. Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine

    Swier, L. J. Y. M., Monjas, L., Guskov, A., de Voogd, A. R., Erkens, G. B., Slotboom, D. J. & Hirsch, A. K. H., 23-Mar-2015, In : ChemBioChem. 16, 5, p. 819-826 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  16. Structural diversity of ABC transporters

    ter Beek, J., Guskov, A. & Slotboom, D. J., Apr-2014, In : Journal of general physiology. 143, 4, p. 419-435 17 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  17. Structure and pharmacological studies of the anaesthetic 1-(3-n-butoxypropyl)-4-benzoyloxypiperidin hydrochloride and its complex with beta-cyclodextrin in solution. NMR and IR-spectroscopy data

    Kemelbekov, U., Saipov, A., Abdildanova, A., Ospanov, I., Luo, Y., Guskov, A., Saenger, W., Imachova, S., Nasyrova, S. & Pichkhadze, G., Dec-2013, In : Journal of inclusion phenomena and macrocyclic chemistry. 77, 1-4, p. 249-257 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  18. Crystal structure of a substrate-free aspartate transporter

    Jensen, S., Guskov, A., Rempel, S., Hänelt, I. & Slotboom, D. J., Oct-2013, In : Nature Structural & Molecular Biology. 20, 10, p. 1224-1226 3 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  19. Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria

    Fulyani, F., Schuurman-Wolters, G. K., Vujicic - Zagar, A., Guskov, A., Slotboom, D-J. & Poolman, B., 8-Oct-2013, In : Structure. 21, 10, p. 1879-1888 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  20. Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport

    Nordin, N., Guskov, A., Phua, T., Sahaf, N., Xia, Y., Lu, S., Eshaghi, H. & Eshaghi, S., 1-May-2013, In : Biochemical Journal. 451, 3, p. 365-374 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  21. Comprehensive analysis and identification of the human STIM1 domains for structural and functional studies

    How, J., Zhang, A., Phillips, M., Reynaud, A., Lu, S. Y., Pan, L. X., Ho, H. T., Yau, Y. H., Guskov, A., Pervushin, K., Shochat, S. G. & Eshaghi, S., 8-Jan-2013, In : PLoS ONE. 8, 1, 12 p., e53979.

    Research output: Contribution to journalArticleAcademicpeer-review

  22. Structural basis of ligand recognition in 5-HT3 receptors

    Kesters, D., Thompson, A. J., Brams, M., van Elk, R., Spurny, R., Geitmann, M., Villalgordo, J. M., Guskov, A., Danielson, U. H., Lummis, S. C. R., Smit, A. B. & Ulens, C., Jan-2013, In : Embo Reports. 14, 1, p. 49-56 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  23. Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA

    Guskov, A., Nordin, N., Reynaud, A., Engman, H., Lundbäck, A-K., Jong, A. J. O., Cornvik, T., Phua, T. & Eshaghi, S., 6-Nov-2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 45, p. 18459-18464 6 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  24. The mechanisms of Mg2+ and Co2+ transport by the CorA family of divalent cation transporters

    Guskov, A. & Eshaghi, S., 2012, In : Current topics in membranes. 69, p. 393-414 22 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  25. Structural basis of cyanobacterial photosystem II Inhibition by the herbicide terbutryn

    Broser, M., Glöckner, C., Gabdulkhakov, A., Guskov, A., Buchta, J., Kern, J., Müh, F., Dau, H., Saenger, W. & Zouni, A., 6-May-2011, In : The Journal of Biological Chemistry. 286, 18, p. 15964-15972 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  26. Lipids in photosystem II: Multifunctional cofactors

    Kern, J. & Guskov, A., 13-Apr-2011, In : Journal of Photochemistry and Photobiology B: Biology. 104, 1-2, p. 19-34 16 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  27. Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein

    Brams, M., Gay, E. A., Sáez, J. C., Guskov, A., van Elk, R., van der Schors, R. C., Peigneur, S., Tytgat, J., Strelkov, S. V., Smit, A. B., Yakel, J. L. & Ulens, C., 11-Feb-2011, In : The Journal of Biological Chemistry. 286, 6, p. 4420-4428 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  28. Pharmacology and structures of the free base of the anaesthetic kazcaine and its complex with beta-cyclodextrin

    Kemelbekov, U. S., Hagenbach, A., Lentz, D., Imachova, S. O., Pichkhadze, G. M., Rustembekov, Z. I., Beketov, K. M., Praliev, K. D., Gabdulkhakov, A., Guskov, A. & Saenger, W., Dec-2010, In : Journal of inclusion phenomena and macrocyclic chemistry. 68, 3-4, p. 323-330 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  29. Crystal structure of monomeric photosystem II from Thermosynechococcus elongatus at 3.6-a resolution

    Broser, M., Gabdulkhakov, A., Kern, J., Guskov, A., Müh, F., Saenger, W. & Zouni, A., 20-Aug-2010, In : The Journal of Biological Chemistry. 285, 34, p. 26255-26262 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  30. Recent progress in the crystallographic studies of photosystem II

    Guskov, A., Gabdulkhakov, A., Broser, M., Glöckner, C., Hellmich, J., Kern, J., Frank, J., Müh, F., Saenger, W. & Zouni, A., 26-Apr-2010, In : Chemphyschem : a European journal of chemical physics and physical chemistry. 11, 6, p. 1160-1171 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  31. Lipids in the Structure of Photosystem I, Photosystem II and the Cytochrome b6f Complex

    Kern, J., Zouni, A., Guskov, A. & Krauss, N., 2009, Lipids in Photosynthesis: Essential and Regulatory Functions. Wada, H. & Murata, N. (eds.). Dordrecht, The Netherlands: Springer, p. 203-241 39 p. (Advances in Photosynthesis and Respiration; vol. 30).

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

  32. Probing the accessibility of the Mn(4)Ca cluster in photosystem II: Channels calculation, noble gas derivatization, and cocrystallization with DMSO

    Gabdulkhakov, A., Guskov, A., Broser, M., Kern, J., Müh, F., Saenger, W. & Zouni, A., 9-Sep-2009, In : Structure. 17, 9, p. 1223-34 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  33. Cyanobacterial photosystem II at 2.9-A resolution and the role of quinones, lipids, channels and chloride

    Guskov, A., Kern, J., Gabdulkhakov, A., Broser, M., Zouni, A. & Saenger, W., Mar-2009, In : Nature Structural & Molecular Biology. 16, 3, p. 334-342 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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Prizes
  1. NWO Start Up grant

    Albert Guskov (Recipient), 6-Feb-2018

    Prize: Fellowship awarded competitivelyAcademic

  2. Vidi Grant

    Albert Guskov (Recipient), 2015

    Prize: Fellowship awarded competitivelyAcademic

View all (2) »

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