drs. A. Felzen

Telefoon:

E-mail:

a.felzen umcg.nl

Research interests

Cholestatic liver disease with a focus on progressive familial intrahepatic cholestasis (PFIC) and primary sclerosing cholangitis (PSC).

Publicaties

EASL Clinical Practice Guidelines on genetic cholestatic liver diseases

European Association for the Study of the Liver, aug.-2024, In: Journal of Hepatology. 81, 2, blz. 303-325 23 blz.

Onderzoeksoutput: Article › › peer review

The spectrum of Progressive Familial Intrahepatic Cholestasis diseases: Update on pathophysiology and emerging treatments

Felzen, A. & Verkade, H. J., nov.-2021, In: European journal of medical genetics. 64, 11, 8 blz., 104317.

Onderzoeksoutput: Review article › peer review

Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency

NAtural course and Prognosis of PFIC and Effect of biliary Diversion (NAPPED) Consortium, Felzen, A., van Wessel, D. B. E., Gonzales, E., Thompson, R. J., Jankowska, I., Shneider, B. L., Sokal, E., Grammatikopoulos, T., Kadaristiana, A., Jacquemin, E., Spraul, A., Lipiński, P., Czubkowski, P., Rock, N., Shagrani, M., Broering, D., Nicastro, E., Kelly, D. & Nebbia, G., Arnell, H., Fischler, B., Hulscher, J. B. F., Serranti, D., Arikan, C., Polat, E., Debray, D., Lacaille, F., Goncalves, C., Hierro, L., Muñoz Bartolo, G., Mozer-Glassberg, Y., Azaz, A., Brecelj, J., Dezsőfi, A., Calvo, P. L., Grabhorn, E., Hartleif, S., van der Woerd, W. J., Kamath, B. M., Wang, J.-S., Li, L., Durmaz, Ö., Kerkar, N., Jørgensen, M. H., Fischer, R., Jimenez-Rivera, C., Alam, S., Cananzi, M., Laverdure, N., Ferreira, C. T., Ordoñez Guerrero, F., Wang, H., Sency, V., Kim, K. M., Chen, H.-L., de Carvalho, E., Fabre, A., Bernabeu, J. Q., Zellos, A., Alonso, E. M., Sokol, R. J., Suchy, F. J., Loomes, K. M., McKiernan, P. J., Rosenthal, P., Turmelle, Y., Horslen, S., Schwarz, K., Bezerra, J. A., Wang, K., Hansen, B. E. & Verkade, H., feb.-2023, In: JHEP reports : innovation in hepatology. 5, 2, 12 blz., 100626.

Onderzoeksoutput: Article › › peer review

4188 | Cholangiocyte Human Endogenous Retroviruses Drive a Type-I Interferon Response via RIG-I/MAVS Pathway in PSC

Splinter, P. L., Felzen, A., Morgenthaler, O., Turner, C., Gores, G., LaRusso, N. F. & O'Hara, S. P., nov.-2025, In: Hepatology. 82, S1, blz. S1936-S1937 2 blz.

Onderzoeksoutput: Meeting Abstract ›

Axonal Regeneration in Cross-Face Nerve Grafts - Do Axon Counts Decline Over Time?

Felzen, A., Millesi, E., Robertson, C. E., Gibreel, W. & Mardini, S., 17-jan.-2025.

Onderzoeksoutput: Poster ›

Axon Counts and Long-term Clinical Outcomes in Patients with Cross-Face Nerve Grafts with Extended Timeframe

Felzen, A., Millesi, E., Robertson, C. E., Gibreel, W. & Mardini, S., 2025.

Onderzoeksoutput: Abstract ›

Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress

O'Hara, S. P., Splinter, P. L., Felzen, A., Turner, C. A., Morgenthaler, O. T., Gores, G. J. & LaRusso, N. F., 2025, In: Cellular and molecular gastroenterology and hepatology. 19, 10, 23 blz., 101547.

Onderzoeksoutput: Article › › peer review

Extended Sural Nerve Harvest: A Technique to Gain Additional Graft Length

Millesi, E., Gates-Tanzer, L., Felzen, A., Wang, H., Gibreel, W. & Mardini, S., 24-jun.-2025, (E-pub ahead of print) In: Plastic and Reconstructive Surgery. 36 blz.

Onderzoeksoutput: Article › › peer review

Generation and characterization of a mouse model for bile salt export pump deficiency with the p.E297G mutation

Felzen, A., Hof, W. F. J., de Vries, H., Hovingh, M. V., Havinga, R., Mulder, N. L., Koehorst, M., Kloosterhuis, N., Smit, M., Huijkman, N., van de Sluis, B., de Boer, J. F., Kuipers, F. & Verkade, H. J., 17-okt.-2025, (E-pub ahead of print) In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 54 blz., 159697.

Onderzoeksoutput: Article › › peer review

SAT-387 Trajectories of serum bile acid levels and their determinants in progressive familial intrahepatic cholestasis: insights from the NAPPED consortium

Huisman, P., Verkade, H. J., Groot, A. D. E. D., Nomden, M., Felzen, A., Gonzaleès, E., Jankowska, I., Shneider, B., Sokal, E., Thompson, R. J., Wang, J.-S., Liting, L., Jacquemin, E., Lipinèski, P., Czubkowski, P., Grammatikopoulos, T., Kadaristiana, A., Arnell, H., Fischler, B. & Woerd, W. L. V. D., Nicastro, E., D’Antiga, L., Alam, S., Shagrani, M., Broering, D. C., Kamath, B. M., Zellos, A., Gupte, G., Calvo, P. L., Grabhorn, E., Debray, D., Cananzi, M., Ruiz, M., Jimenez-Rivera, C., Kim, K., Llanillo, L. H., Bartolo, G. M., Durmaz, O., Vogel, G.-F., Sturm, E., Indolfi, G., Fabre, A., Shteyer, E., Jørgensen, M. H., Ko, J. S., Rock, N., Azaz, A., Glassberg, Y. M., Ferreira, S. & Mian, P., mei-2025, In: Journal of Hepatology. 82, blz. S746-S747 2 blz.

Onderzoeksoutput: Meeting Abstract ›

Alle (16) publicaties

Pers/media

Antonia Felzen awarded the Alex Mowat Prize 2023

Felzen, A.

29/05/2023

Pers / media: Onderzoek ›

Toekenningen KNAW Ter Meulen Beurs 2023

Felzen, A.

29/06/2023

Pers / media: Onderzoek ›

Alle (2) pers/media

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