dr. A. Diepstra

pathologist and post-doc researcher

dr. A. Diepstra
a.diepstra umcg.nl


Research interests

I am a hematopathologist at the University Medical Center Groningen and a principal investigator in the SALL (stem cells, aging, leukemia and lymphoma) program of the CRCG (Cancer Research Center Groningen). My main research interest involves malignant lymphoma, in particular Hodgkin lymphoma, with a strong focus on interactions between tumor cells and the microenvironment. In my PhD thesis "Classical Hodgkin lymphoma: population based studies on HLA and EBV (2007)" I discovered that the HLA system is intricately involved in Hodgkin lymphoma susceptibility, pathogenesis and prognosis and published these findings in the Lancet and Journal of Clinical Oncology. I secured three Dutch Cancer Society grants to do functional follow-up studies on these findings. Fruitful international collaborations involve the Interlymph consortium on genome wide association studies, the Lymphoma group of the EORTC and various groups in the UK, Canada and the US. My areas of expertise are: immunology, tumor cell biology, association studies and molecular diagnostics in pathology.   

  1. Microenvironment, cross-talk, and immune escape mechanisms

    Visser, L., Veldman, J., Poppema, S., van den Berg, A. & Diepstra, A., 1-Jan-2020, Hematologic Malignancies. SPRINGER, p. 69-86 18 p. (Hematologic Malignancies).

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

  2. Combining brentuximab vedotin with dexamethasone, high-dose cytarabine and cisplatin as salvage treatment in relapsed or refractory Hodgkin lymphoma: the phase II HOVON/LLPC Transplant BRaVE study

    Kersten, M. J., Driessen, J., Zijlstra, J. M., Plattel, W. J., Morschhauser, F., Lugtenburg, P. J., Brice, P., Hutchings, M., Gastinne, T., Liu, R., Burggraaff, C. N., Nijland, M., Tonino, S. H., Arens, A. I. J., Valkema, R., van Tinteren, H., Lopez-Yurda, M., Diepstra, A., De Jong, D. & Hagenbeek, A., 9-Apr-2020, In : Haematologica.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Diagnostiek bij agressief B-cel non-Hodgkin lymfoom

    Diepstra, A., 1-Feb-2020, In : Nederlands Tijdschrift voor Hematologie. p. 3-8

    Research output: Contribution to journalReview articleAcademicpeer-review

  4. B-cell lymphomas

    Diepstra, A., 1-Sep-2019

    Research output: Other contributionAcademic

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Press / Media
  1. Een lab dat levens redt - a lab that saves lives

    Arjan Diepstra


    1 item of Media coverage

    Press/Media: Public Engagement ActivitiesPopular

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  1. Novel molecular and immunological aspects of Hodgkin and diffuse large B-cell lymphoma

    Arjan Diepstra (Invited speaker)

    Activity: Talk or presentationAcademic

  2. Interlymph annual meeting

    Arjan Diepstra (Chair)

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

  3. Interlymph annual meeting

    Arjan Diepstra (Invited speaker)

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

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  1. Karl Musshoff Prize

    Arjan Diepstra (Recipient), 24-Oct-2016


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