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University of Groningenfounded in 1614  -  top 100 university
Research Zernike (ZIAM) Supramolecular Chemistry

Publications

2025

Balderston, D. E., Feo, E., Leonescu, A., Stevens, M., Wilmshurst, A. M., Gale, P. A., Haynes, C. J. E., Williams, G. T., & Hiscock, J. R. (2025). Advances in applied supramolecular technologies 2021–2025. Chemical Society Reviews, 54, 8888-8924. https://doi.org/10.1039/D4CS01037J
Luo, Y., Luo, Y., Liu, Y., Huang, Y., Yu, P., Ma, H., Li, X., Zhang, Z., Zhang, C., Chen, C., Gale, P. A., & Bao, G. (2025). A hybrid strategy to enhance small-sized upconversion nanocrystals. Biosensors and Bioelectronics, 271, Article 117003. https://doi.org/10.1016/j.bios.2024.117003
Maslowska-Jarzyna, K., Rooijmans, S., McNaughton, D. A., Ryder, W. G., York, E., Tromp, M., & Gale, P. A. (2025). Anion transport in biologically relevant lipid mixtures. Chemical Communications, 61(21), 4184-4187. https://doi.org/10.1039/d5cc00409h
Grzywaczyk, A., Rojewska, M., Smułek, W., McNaughton, D. A., Prochaska, K., Gale, P. A., & Kaczorek, E. (2025). Glycyrrhiza glabra L. Saponins Modulate the Biophysical Properties of Bacterial Model Membranes and Affect Their Interactions with Tobramycin. Langmuir, 41(18), 11701-11710. https://doi.org/10.1021/acs.langmuir.5c00927
Hawkins, B. A., Adair, L. D., Ryder, W. G., Du, J. J., Najib, E., New, E. J., Gale, P. A., Platts, J. A., Groundwater, P. W., & Hibbs, D. E. (2025). Influence of Halogen Substituents on the Photophysical Properties of 7-Hydroxycoumarin: Insights from Experimental and Theoretical Studies. Chemphyschem, 26(5), Article e202400812. https://doi.org/10.1002/CPHC.202400812
Fares, M., Alsherbiny, M., Elkelesh, I. A., Said, M. A., Maklad, R. M., Lewis, W., Li, C. G., Eldehna, W. M., Groundwater, P. W., Gale, P. A., & Keller, P. A. (2025). Investigating the multi-mechanistic anticancer effects of 4-bisarylurea thiouracil derivatives in breast cancer cells. Bioorganic Chemistry, 162, Article 108581. https://doi.org/10.1016/j.bioorg.2025.108581
Liu, Y., Huang, Y., Luo, Y., Luo, Y., Jiang, L., Gallego-Ortega, D., Cheng, Y. Y., Gale, P. A., & Bao, G. (2025). Lanthanide-doped nanoprobes for microRNA detection. Coordination Chemistry Reviews, 536, Article 216644. https://doi.org/10.1016/j.ccr.2025.216644
Umashankar, B., Pazderka, C., York, E., King, A., Rahman, M. K., Choucair, H., Bourget, K., Gale, P. A., Rawling, T., & Murray, M. (2025). Mitochondrial targeting and anticancer cell killing by arylurea-fatty acids containing in-chain sulfur atoms. Journal of Pharmaceutical Sciences, 114(9), Article 103933. https://doi.org/10.1016/j.xphs.2025.103933
Rajasekar, S., York, E., McNaughton, D. A., Pacchini, E., Gertner, D. S., Lockwood, T. E., Ryder, W. G., Rawling, T., & Gale, P. A. (2025). Photoactivatable aryl amide substituted fatty acid protonophores. Supramolecular Chemistry, 36(7-8), 235-242. https://doi.org/10.1080/10610278.2025.2549458
Maslowska-Jarzyna, K., York, E., Feo, E., Maklad, R. M., Bao, G., Fares, M., & Gale, P. A. (2025). Recent discoveries in anion receptor chemistry. Chem, 11(8), Article 102695. https://doi.org/10.1016/j.chempr.2025.102695
Bai, X., Liao, J., Lou, B., Zhang, Y., Zhao, H., Zi, Y., Li, Y., Tang, W., Mandl, G. A., Huang, A., Song, Z., Qiu, J., Gale, P. A., Capobianco, J. A., Ma, C., & Yang, Z. (2025). Reversible Photochromism and Multicolor Luminescence Modulation for X-Ray Detection and Secure Information Encryption. Advanced Functional Materials, Article e06583. Advance online publication. https://doi.org/10.1002/ADFM.202506583
Ryder, W. G., Levina, A., Graziotto, M. E., Hawkins, B. A., Hibbs, D. E., New, E. J., & Gale, P. A. (2025). Subcellular targeted anion transporters. Chem, 11(1), Article 102247. https://doi.org/10.1016/j.chempr.2024.07.009
Gilchrist, A. M., McNaughton, D. A., Fares, M., Wu, X., Hawkins, B. A., Butler, S. J., Hibbs, D. E., & Gale, P. A. (2025). Tetralactam-based anion transporters. Chem, 11(1), Article 102329. https://doi.org/10.1016/j.chempr.2024.09.028
Pacchini, E., McNaughton, D., Gale, P., Pye, A., Wilson, K., & Rawling, T. (2025). The role of transmembrane proton transport rate in mild mitochondrial uncoupling produced by arylamide substituted fatty acids. ChemRxiv. https://doi.org/10.26434/chemrxiv-2025-7lt30
Pacchini, E., McNaughton, D. A., Pye, A., Wilson, K. A., Gale, P. A., & Rawling, T. (2025). The role of transmembrane proton transport rates in mild mitochondrial uncoupling by arylamide substituted fatty acids. Chemical Science. Advance online publication. https://doi.org/10.1039/d5sc06530e
Li, J., Catal, O., Marques, I., Mcnaughton, D. A., Maklad, R. M., Ryder, W. G., Hill, M. J. S., Seddon, A., Lewis, W., Adams, D. J., Felix, V., Wu, X., & Gale, P. A. (2025). Trapping Anions within Stacks of Tetra-Urea Macrocycles. Journal of the American Chemical Society, 147(4), 3392–3401. https://doi.org/10.1021/JACS.4C14194
Ryder, W., Levina, A., Nielsen, M., Lewis, W., New, E., & Gale, P. A. (2025). Urea-based anion transporters. ChemRxiv. https://doi.org/10.26434/chemrxiv-2025-nc9sh

2024

York, E., McNaughton, D. A., Gertner, D. S., Gale, P. A., Murray, M., & Rawling, T. (2024). Expanding the π-system of Fatty Acid-Anion Transporter Conjugates Modulates Their Mechanism of Proton Transport and Mitochondrial Uncoupling Activity. Chemistry - A European Journal, 30(46), Article e202400931. https://doi.org/10.1002/CHEM.202400931
Picci, G., Montis, R., Gilchrist, A. M., Gale, P. A., & Caltagirone, C. (2024). Fluorescent and colorimetric sensors for anions: Highlights from 2020 to 2022. Coordination Chemistry Reviews, 501, Article 215561. https://doi.org/10.1016/j.ccr.2023.215561
Ryder, W. G., Wu, E. G., Chen, L., Fares, M., McNaughton, D. A., Tran, K., Yu, C., & Gale, P. A. (2024). Furazan bis-ureas: A heterocyclic scaffold for anion binding and transport. Organic Chemistry Frontiers, 11(5), 1290-1298. https://doi.org/10.1039/D3QO01956J
McNaughton, D. A., York, E., Rawling, T., & Gale, P. A. (2024). N,N′-Dimethylsquaramide as a central scaffold for anionophore design. Organic & Biomolecular Chemistry, 22(24), 4868-4876. https://doi.org/10.1039/D4OB00703D
Wang, P., Fares, M., Eladwy, R. A., Bhuyan, D. J., Wu, X., Lewis, W., Loeb, S. J., Macreadie, L. K., & Gale, P. A. (2024). Platinum-based metal complexes as chloride transporters that trigger apoptosis. Chemical Science, 15(29), 11584-11593. https://doi.org/10.1039/D4SC02115K
Liu, Y., Ning, L., Luo, Y., Huang, Y., He, Z., Ma, H., Zhao, Y., Zhang, J., Liu, D., Fu, L., Langford, S. J., Gale, P. A., Luo, Y., & Bao, G. (2024). Stabilizing Dye-Sensitized Upconversion Hybrids by Cyclooctatetraene. Nano Letters, 24(40), 12486–12492. https://doi.org/10.1021/ACS.NANOLETT.4C03391
Feo, E., & Gale, P. A. (2024). Therapeutic synthetic anion transporters. Current Opinion in Chemical Biology, 83, Article 102535. https://doi.org/10.1016/j.cbpa.2024.102535

2023

Fares, M., Wu, X., McNaughton, D. A., Gilchrist, A. M., Lewis, W., Keller, P. A., Arias-Betancur, A., Fontova, P., Pérez-Tomás, R., & Gale, P. A. (2023). A potent fluorescent transmembrane HCl transporter perturbs cellular pH and promotes cancer cell death. Organic & Biomolecular Chemistry, 21(12), 2509-2515. https://doi.org/10.1039/D3OB00128H
York, E., McNaughton, D. A., Duman, M.-N., Gale, P. A., & Rawling, T. (2023). Fatty Acid-Activated Proton Transport by Bisaryl Anion Transporters Depolarises Mitochondria and Reduces the Viability of MDA-MB-231 Breast Cancer Cells. Biomolecules, 13(8), Article 1202. https://doi.org/10.3390/biom13081202
Gilchrist, A. M., Wu, X., Hawkins, B. A., Hibbs, D. E., & Gale, P. A. (2023). Fluorinated tetrapodal anion transporters. Iscience, 26(2), Article 105988. https://doi.org/10.1016/j.isci.2023.105988
McNaughton, D. A., Ryder, W. G., Gilchrist, A. M., Wang, P., Fares, M., Wu, X., & Gale, P. A. (2023). New insights and discoveries in anion receptor chemistry. Chem, 9(11), 3045-3112. https://doi.org/10.1016/J.CHEMPR.2023.07.006
Brennan, L. E., Kumawat, L. K., Piatek, M. E., Kinross, A. J., Mcnaughton, D. A., Marchetti, L., Geraghty, C., Wynne, C., Tong, H., Kavanagh, O. N., O'Sullivan, F., Hawes, C. S., Gale, P. A., Kavanagh, K., & Elmes, R. B. P. (2023). Potent antimicrobial effect induced by disruption of chloride homeostasis. Chem, 9(11), 3138-3158. https://doi.org/10.1016/J.CHEMPR.2023.07.014
MacDermott-Opeskin, H., Clarke, C., Wu, X., Roseblade, A., York, E., Pacchini, E., Roy, R., Cranfield, C., Gale, P. A., O'Mara, M. L., Murray, M., & Rawling, T. (2023). Protonophoric and mitochondrial uncoupling activity of aryl-carbamate substituted fatty acids. Organic & Biomolecular Chemistry, 21(1), 132-139. https://doi.org/10.1039/D2OB02049A

2022

Zhou, W., Li, A., Gale, P. A., & He, Q. (2022). A highly selective superphane for ReO4− recognition and extraction. Cell Reports Physical Science, 3(5), Article 100875. https://doi.org/10.1016/j.xcrp.2022.100875
Moiteiro, C., Marques, I., Ryder, W. G., Cachatra, V., Carvalho, S., Chen, LJ., Goodfellow, B. J., Gale, P. A., & Félix, V. (2022). Binding and Transport Properties of a Benzo[b]thiophene‐Based Mono‐(thio)urea Library. European Journal of Organic Chemistry, 2022(3), Article e202101484. https://doi.org/10.1002/ejoc.202101484
Zhao, Z., Tang, B., Yan, X., Wu, X., Li, Z., Gale, P. A., & Jiang, Y.-B. (2022). Crown ether-thiourea conjugates as ion transporters. Frontiers of chemical science and engineering, 16(1), 81–91. https://doi.org/10.1007/S11705-021-2049-7
Howe, E. N. W., Chang, V. V. T., Wu, X., Fares, M., Lewis, W., Macreadie, L. K., & Gale, P. A. (2022). Halide-selective, proton-coupled anion transport by phenylthiosemicarbazones. Biochimica et Biophysica Acta - Biomembranes, 1864(2), Article 183828. https://doi.org/10.1016/j.bbamem.2021.183828
Wu, X., Gilchrist, A. M., & Gale, P. A. (2022). Janus metal-organic layer functioning as a biomimetic photosynthetic reaction center. Chem, 8(3), 604-606. https://doi.org/10.1016/j.chempr.2022.01.019
Wu, X., Wang, P., Lewis, W., Jiang, Y.-B., & Gale, P. A. (2022). Measuring anion binding at biomembrane interfaces. Nature Communications, 13, Article 4623. https://doi.org/10.1038/s41467-022-32403-z
Chen, LJ., Wu, X., Gilchrist, A. M., & Gale, P. A. (2022). Organoplatinum Compounds as Anion‐Tuneable Uphill Hydroxide Transporters. Angewandte Chemie, 134(19), Article e202116355. https://doi.org/10.1002/ange.202116355
Macreadie, L. K., Gilchrist, A. M., McNaughton, D. A., Ryder, W. G., Fares, M., & Gale, P. A. (2022). Progress in anion receptor chemistry. Chem, 8(1), 46-118. https://doi.org/10.1016/j.chempr.2021.10.029
Chau, C. V., Sen, S., Sedgwick, A. C., Gale, P. A., Pantos, G. D., Kim, S. K., Park, J. S., Tomat, E., Arambula, J. F., Gorden, A. E. V., & Furuta, H. (2022). Solving world problems with pyrrole: 65th birthday tribute to Prof. Jonathan L. Sessler. Chem, 8(3), 587-598. https://doi.org/10.1016/j.chempr.2022.02.005
York, E., McNaughton, D. A., Roseblade, A., Cranfield, C. G., Gale, P. A., & Rawling, T. (2022). Structure-Activity Relationship and Mechanistic Studies of Bisaryl Urea Anticancer Agents Indicate Mitochondrial Uncoupling by a Fatty Acid-Activated Mechanism. ACS chemical biology, 17(8), 2065-2073. https://doi.org/10.1021/acschembio.1c00807
Fares, M., Canfield, P., Alsherbiny, M. A., Lewis, W., Willis, A. C., Guang Li, C., Neyts, J., Jochmans, D., Gale, P. A., & Keller, P. A. (2022). Synthesis, X-ray crystallographic analysis, DFT studies and biological evaluation of triazolopyrimidines and 2-anilinopyrimidines. Journal of Molecular Structure, 1252, Article 132092. https://doi.org/10.1016/j.molstruc.2021.132092
Jolliffe, K. A., & Gale, P. A. (2022). The supramolecular chemistry of anions. Organic and Biomolecular Chemistry, 20(4), 713-714. https://doi.org/10.1039/d1ob90183d

2021

McNaughton, D., Macreadie, L., & Gale, P. A. (2021). Acridinone-based anion transporters. ChemRxiv. https://doi.org/10.33774/chemrxiv-2021-6b4tx
Williams, G. T., Haynes, C. J. E., Fares, M., Caltagirone, C., Hiscock, J. R., & Gale, P. A. (2021). Advances in applied supramolecular technologies. Chemical Society Reviews, 50(4), 2737-2763. https://doi.org/10.1039/D0CS00948B
McNaughton, D. A., Fares, M., Picci, G., Gale, P. A., & Caltagirone, C. (2021). Advances in fluorescent and colorimetric sensors for anionic species. Coordination Chemistry Reviews, 427, Article 213573. https://doi.org/10.1016/J.CCR.2020.213573
Wu, X., Macreadie, L. K., & Gale, P. A. (2021). Anion binding in metal-organic frameworks. Coordination Chemistry Reviews, 432, Article 213708. https://doi.org/10.1016/J.CCR.2020.213708
Yang, J., Yu, G., Sessler, J. L., Shin, I., Gale, P. A., & Huang, F. (2021). Artificial transmembrane ion transporters as potential therapeutics. Chem, 7(12), 3256-3291. https://doi.org/10.1016/j.chempr.2021.10.028
Chen, L.-J., Humphrey, S. J., Zhu, J.-L., Zhu, F.-F., Wang, X.-Q., Wang, X., Wen, J., Yang, H.-B., & Gale, P. A. (2021). A Two-Dimensional Metallacycle Cross-Linked Switchable Polymer for Fast and Highly Efficient Phosphorylated Peptide Enrichment. Journal of the American Chemical Society, 143(22), 8295–8304. https://doi.org/10.1021/jacs.0c12904
Wang, P., Wu, X., & Gale, P. A. (2021). Carbazole-based bis-ureas and thioureas as electroneutral anion transporters. Supramolecular Chemistry, 33(4), 143-149 . https://doi.org/10.1080/10610278.2021.1946539
Mcnaughton, D. A., To, T. Y. T., Hawkins, B. A., Hibbs, D. E., & Gale, P. A. (2021). Delivering anion transporters to lipid bilayers in water. Organic and Biomolecular Chemistry, 19(44), 9624-9628. https://doi.org/10.1039/d1ob02041b
Wu, X., & Gale, P. A. (2021). Measuring anion transport selectivity: a cautionary tale. Chemical Communications, 57(33), 3979-3982. https://doi.org/10.1039/D1CC01038G
Gilchrist, A. M., Wang, P., Carreira-Barral, I., Alonso-Carrillo, D., Wu, X., Quesada, R., & Gale, P. A. (2021). Supramolecular methods: The 8-hydroxypyrene-1,3,6-trisulfonic acid (HPTS) transport assay. Supramolecular Chemistry, 33(7), 325-344. https://doi.org/10.1080/10610278.2021.1999956
Park, S. H., Hwang, I., McNaughton, D. A., Kinross, A. J., Howe, E. N. W., He, Q., Xiong, S., Kilde, M. D., Lynch, V. M., Gale, P. A., Sessler, J. L., & Shin, I. (2021). Synthetic Na+/K+ exchangers promote apoptosis by disturbing cellular cation homeostasis. Chem, 7(12), 3325-3339. https://doi.org/10.1016/j.chempr.2021.08.018

2020

Gale, P. A. (2020). A Calix[4]pyrrole-Based Selective Amino Acid Transporter. Chem, 6(11), 2873-2875. https://doi.org/10.1016/J.CHEMPR.2020.10.005
Chen, L., Berry, S. N., Wu, X., Howe, E. N. W., & Gale, P. A. (2020). Advances in Anion Receptor Chemistry. Chem, 6(1), 61-141. https://doi.org/10.1016/J.CHEMPR.2019.12.002
Davis, J. T., Gale, P. A., & Quesada, R. (2020). Advances in anion transport and supramolecular medicinal chemistry. Chemical Society Reviews, 49(16), 6056-6086. https://doi.org/10.1039/C9CS00662A
Rawling, T., MacDermott-Opeskin, H., Roseblade, A., Pazderka, C., Clarke, C., Bourget, K., Wu, X., Lewis, W., Noble, B., Gale, P. A., O'Mara, M. L., Cranfield, C., & Murray, M. (2020). Aryl urea substituted fatty acids: A new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter. Chemical Science, 11(47), 12677-12685. https://doi.org/10.1039/D0SC02777D
Gale, P. A. (2020). Development of a Library of Thiophene‐Based Drug‐Like Lego Molecules: Evaluation of Their Anion Binding, Transport Properties, and Cytotoxicity. Chemistry – A European Journal, 26(4), 888-899. https://doi.org/10.1002/chem.201904255
Gale, P. A. (2020). Prospects and Challenges in Anion Recognition and Transport. Chem, 6(6), 1296-1309. https://doi.org/10.1016/j.chempr.2020.05.001
Gale, P. A. (2020). Selective anion transport mediated by strap-extended calixpyrroles. Journal of Porphyrins and Phthalocyanines, 24(1-3), 473-479. https://doi.org/10.1142/s1088424619501591
Fares, M., Wu, X., Ramesh, D., Lewis, W., Keller, P. A., Howe, E. N. W., Pérez‐Tomás, R., & Gale, P. A. (2020). Stimuli‐Responsive Cycloaurated “OFF‐ON” Switchable Anion Transporters. Angewandte Chemie, 59(40), 17614-17621. https://doi.org/10.1002/ange.202006392
Gilchrist, A. M., Chen, L., Wu, X., Lewis, W., Howe, E. N. W., Macreadie, L. K., & Gale, P. A. (2020). Tetrapodal Anion Transporters. Molecules, 25(21), Article 5179. https://doi.org/10.3390/molecules25215179

2019

Li, H., Valkenier, H., Thorne, A. G., Dias, C. M., Cooper, J. A., Kieffer, M., Busschaert, N., Gale, P. A., Sheppard, D. N., & Davis, A. P. (2019). Anion carriers as potential treatments for cystic fibrosis: transport in cystic fibrosis cells, and additivity to channel-targeting drugs. Chemical Science, 10(42), 9663-9672. https://doi.org/10.1039/C9SC04242C
Zhang, S., Wang, Y., Xie, W., Howe, E. N. W., Busschaert, N., Sauvat, A., Leduc, M., Gomes-da-Silva, L. C., Chen, G., Martins, I., Deng, X., Maiuri, L., Kepp, O., Soussi, T., Gale, P. A., Zamzami, N., & Kroemer, G. (2019). Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux (Cell Death & Disease, (2019), 10, 3, (242), 10.1038/s41419-019-1474-8). Cell Death and Disease, 10, Article 301. https://doi.org/10.1038/s41419-019-1536-y
Wu, X., Small, J. R., Cataldo, A., Withecombe, A. M., Turner, P., & Gale, P. A. (2019). Cover Picture: Voltage‐Switchable HCl Transport Enabled by Lipid Headgroup–Transporter Interactions (Angew. Chem. Int. Ed. 42/2019). Angewandte Chemie International Edition, 58(42), 14775. https://doi.org/10.1002/anie.201911407
Chen, X.-X., Lin, X.-Y., Wu, X., Gale, P. A., Anslyn, E. V., & Jiang, Y.-B. (2019). Design of Chiral Supramolecular Polymers Exhibiting a Negative Nonlinear Response. The Journal of Organic Chemistry, 84(22), 14587–14592. https://doi.org/10.1021/acs.joc.9b02166
Park, S.-H., Park, S.-H., Howe, E. N. W., Hyun, J. Y., Chen, L.-J., Hwang, I., Vargas-Zuniga, G., Busschaert, N., Gale, P. A., Sessler, J. L., & Shin, I. (2019). Determinants of Ion-Transporter Cancer Cell Death. Chem, 5(8), 2079-2098. https://doi.org/10.1016/J.CHEMPR.2019.05.001
Howe, E. N. W., & Gale, P. A. (2019). Fatty Acid Fueled Transmembrane Chloride Transport. Journal of the American Chemical Society, 141(27), 10654–10660. https://doi.org/10.1021/jacs.9b02116
Montis, R., Bencini, A., Coles, S. J., Conti, L., Fusaro, L., Gale, P. A., Giorgi, C., Horton, P. N., Lippolis, V., Mapp, L. K., & Caltagirone, C. (2019). Fluoride binding by an anionic receptor: Tuning the acidity of amide NH groups for basic anion hydrogen bonding and recognition. Chemical Communications, 55(19), 2745-2748. https://doi.org/10.1039/c8cc09962f
Spooner, M. J., Li, H., Marques, I., Costa, P. M. R., Wu, X., Howe, E. N. W., Busschaert, N., Moore, S. J., Light, M. E., Sheppard, D. N., Félix, V., & Gale, P. A. (2019). Fluorinated synthetic anion carriers: Experimental and computational insights into transmembrane chloride transport. Chemical Science, 10(7), 1976-1985. https://doi.org/10.1039/C8SC05155K
Barboiu, M., Kumar, M., Baaden, M., Gale, P. A., & Hinds, B. J. (2019). Highlights from the Faraday Discussion on Artificial Water Channels, Glasgow, UK. Chemical Communications, 55(27), 3853-3858. https://doi.org/10.1039/c9cc90112d
Jowett, L. A., Ricci, A., Wu, X., Howe, E. N. W., & Gale, P. A. (2019). Investigating the influence of steric hindrance on selective anion transport. Molecules, 24(7), Article 1278. https://doi.org/10.3390/molecules24071278
Zhang, S., Wang, Y., Xie, W., Howe, E. N. W., Busschaert, N., Sauvat, A., Leduc, M., Gomes-da-Silva, L. C., Chen, G., Martins, I., Deng, X., Maiuri, L., Kepp, O., Soussi, T., Gale, P. A., Zamzami, N., & Kroemer, G. (2019). Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux. Cell Death and Disease, 10, Article 242. https://doi.org/10.1038/s41419-019-1474-8
Jowett, L. A., & Gale, P. A. (2019). Supramolecular methods: The chloride/nitrate transmembrane exchange assay. Supramolecular Chemistry, 31(5), 297-312. https://doi.org/10.1080/10610278.2019.1574017
Wu, X., Wang, P., Turner, P., Lewis, W., Catal, O., Thomas, D. S., & Gale, P. A. (2019). Tetraurea Macrocycles: Aggregation-Driven Binding of Chloride in Aqueous Solutions. Chem, 5(5), 1210-1222. https://doi.org/10.1016/j.chempr.2019.02.023
Wu, X., Small, J. R., Cataldo, A., Withecombe, A. M., Turner, P., & Gale, P. A. (2019). Voltage‐Switchable HCl Transport Enabled by Lipid Headgroup–Transporter Interactions. Angewandte Chemie, 131(42), 15286-15291. https://doi.org/10.1002/ange.201907466

2018

Gale, P. A., Howe, E. N. W., Wu, X., & Spooner, M. J. (2018). Anion receptor chemistry: Highlights from 2016. Coordination Chemistry Reviews, 375, 333-372. https://doi.org/10.1016/j.ccr.2018.02.005
Dias, C. M., Li, H., Valkenier, H., Karagiannidis, L. E., Gale, P. A., Sheppard, D. N., & Davis, A. P. (2018). Anion transport by Ortho -phenylene bis-ureas across cell and vesicle membranes. Organic and Biomolecular Chemistry, 16(7), 1083-1087. https://doi.org/10.1039/c7ob02787g
Spooner, M. J., & Gale, P. A. (2018). A tripodal tris-selenourea anion transporter matches the activity of its thio- analogue but shows distinct selectivity. Supramolecular Chemistry, 30(5-6), 514-519. https://doi.org/10.1080/10610278.2018.1431394
Baaden, M., Barboiu, M., Bill, R. M., Chen, C.-L., Davis, J., Di Vincenzo, M., Freger, V., Fröba, M., Gale, P. A., Gong, B., Hélix-Nielsen, C., Hickey, R., Hinds, B., Hou, J.-L., Hummer, G., Kumar, M., Legrand, Y.-M., Lokesh, M., Mi, B., ... Vögele, M. (2018). Biomimetic water channels: General discussion. Faraday Discussions, 209, 205-229. https://doi.org/10.1039/C8FD90020E
Gale, P. A., & Caltagirone, C. (2018). Fluorescent and colorimetric sensors for anionic species. Coordination Chemistry Reviews, 354, 2-27. https://doi.org/10.1016/j.ccr.2017.05.003
Bao, X., Wu, X., Berry, S. N., Howe, E. N. W., Chang, Y.-T., & Gale, P. A. (2018). Fluorescent squaramides as anion receptors and transmembrane anion transporters. Chemical Communications, 54(11), 1363-1366. https://doi.org/10.1039/c7cc08706c
Pankratova, N., Cuartero, M., Jowett, L. A., Howe, E. N. W., Gale, P. A., Bakker, E., & Crespo, G. A. (2018). Fluorinated tripodal receptors for potentiometric chloride detection in biological fluids. Biosensors and Bioelectronics, 99, 70-76. https://doi.org/10.1016/j.bios.2017.07.001
Marques, I., Costa, P. M. R., Miranda, M. Q., Busschaert, N., Howe, E. N. W., Clarke, H. J., Haynes, C. J. E., Kirby, I. L., Rodilla, A. M., Pérez-Tomás, R., Gale, P. A., & Félix, V. (2018). Full elucidation of the transmembrane anion transport mechanism of squaramides using: In silico investigations. Physical Chemistry Chemical Physics, 20(32), 20796-20811. https://doi.org/10.1039/c8cp02576b
Jowett, L. A., Howe, E. N. W., Wu, X., Busschaert, N., & Gale, P. A. (2018). New Insights into the Anion Transport Selectivity and Mechanism of Tren-based Tris-(thio)ureas. Chemistry - A European Journal, 24(41), 10475-10487. https://doi.org/10.1002/chem.201801463
Cheung, S., Wu, D., Daly, H. C., Busschaert, N., Morgunova, M., Simpson, J. C., Scholz, D., Gale, P. A., & O'Shea, D. F. (2018). Real-Time Recording of the Cellular Effects of the Anion Transporter Prodigiosin. Chem, 4(4), 879-895. https://doi.org/10.1016/j.chempr.2018.02.009
Wu, X., Howe, E. N. W., & Gale, P. A. (2018). Supramolecular Transmembrane Anion Transport: New Assays and Insights. Accounts of Chemical Research, 51(8), 1870–1879. https://doi.org/10.1021/acs.accounts.8b00264

2017

Gale, P. A., Davis, J. T., & Quesada, R. (2017). Anion transport and supramolecular medicinal chemistry. Chemical Society Reviews, 46(9), 2497-2519. https://doi.org/10.1039/c7cs00159b
Busschaert, N., Park, S.-H., Baek, K.-H., Choi, Y. P., Park, J., Howe, E. N. W., Hiscock, J. R., Karagiannidis, L. E., Marques, I., Félix, V., Namkung, W., Sessler, J. L., Gale, P. A., & Shin, I. (2017). A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations. Nature Chemistry, 9, 667–675 . https://doi.org/10.1038/nchem.2706
Daryl Ariawan, A., Webb, J. E. A., Howe, E. N. W., Gale, P. A., Thordarson, P., & Hunter, L. (2017). Cyclic peptide unguisin A is an anion receptor with high affinity for phosphate and pyrophosphate. Organic and Biomolecular Chemistry, 15(14), 2962-2967. https://doi.org/10.1039/C7OB00316A
Yang, Y., Wu, X., Busschaert, N., Furuta, H., & Gale, P. A. (2017). Dissecting the chloride-nitrate anion transport assay. Chemical Communications, 53(66), 9230-9233. https://doi.org/10.1039/c7cc04912a
Jowett, L. A., Howe, E. N. W., Soto-Cerrato, V., Van Rossom, W., Pérez-Tomás, R., & Gale, P. A. (2017). Indole-based perenosins as highly potent HCl transporters and potential anti-cancer agents. Scientific Reports, 7, Article 9397. https://doi.org/10.1038/s41598-017-09645-9
Gibb, B., & Gale, P. (2017). Supramolecular chemistry: Defined. Supramolecular Chemistry, 29(9), 1. Article 633. https://doi.org/10.1080/10610278.2017.1332731
Amabilino, D. B., & Gale, P. A. (2017). Supramolecular chemistry anniversary. Chemical Society Reviews, 46(9), 2376-2377. https://doi.org/10.1039/c7cs90037f

2016

Gale, P. A., Howe, E. N. W., & Wu, X. (2016). Anion Receptor Chemistry. Chem, 1(3), 351-422. https://doi.org/10.1016/j.chempr.2016.08.004
Gale, P. A. (2016). Anion receptors based on organic frameworks: Recent advances. In D. M. P. Mingos (Ed.), 50 Years of Structure and Bonding: The Anniversary Volume (pp. 19-34). (Structure and Bonding; Vol. 72). Springer International Publishing, Cham, Switzerland. https://doi.org/10.1007/430_2015_174
Clarke, H. J., Van Rossom, W., Horton, P. N., Light, M. E., & Gale, P. A. (2016). Anion transport and binding properties of N, N′-(phenylmethylene)dibenzamide based receptors. Supramolecular Chemistry, 28(1-2), 10-17. https://doi.org/10.1080/10610278.2015.1034126
Hiscock, J. R., Wells, N. J., Ede, J. A., Gale, P. A., & Sambrook, M. R. (2016). Biasing hydrogen bond donating host systems towards chemical warfare agent recognition. Organic and Biomolecular Chemistry, 14(40), 9560-9567. https://doi.org/10.1039/c6ob01210h
Share, A. I., Patel, K., Nativi, C., Cho, E. J., Francesconi, O., Busschaert, N., Gale, P. A., Roelens, S., & Sessler, J. L. (2016). Chloride anion transporters inhibit growth of methicillin-resistant: Staphylococcus aureus (MRSA) in vitro. Chemical Communications, 52(48), 7560-7563. https://doi.org/10.1039/c6cc03645g
Kitchen, J. A., & Gale, P. A. (2016). Complexity of Supramolecular Assemblies. In Chirality in Supramolecular Assemblies: Causes and Consequences (pp. 94-141). Wiley-Blackwell. https://doi.org/10.1002/9781118867334.ch4
Last modified:05 January 2026 08.22 a.m.