Zernike Colloquium: Rudi Podgornik - Charges, charge regulations and charge fluctuations
| When: | Th 01-11-2018 16:00 - 17:00 |
| Where: | Lecture Hall: 5111.0080 |
Charges, charge regulations and charge fluctuations
Rudolf Podgornik, School of Physical Sciences and Kavli Institute for Theoretical Sciences, University of Chinese Academy of Sciences, and
CAS Key Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing
There are no net charges in (bio)colloid world, and all of them result from dissociation of chargeable groups, as in e.g., proteins from dissociable amino acid moieties. How do charging equilibria, aka charge regulation, then affect the electrostatic interactions? This is a fundamental problem in biophysics, important for our understanding of interactions between the proteins and proteinaceous aggregates such as viral capsids, but also in the general colloid context, often built on the fictional foundation of fixed charges.
There are no net charges in (bio)colloid world, and all of them result from dissociation of chargeable groups, as in e.g., proteins from dissociable amino acid moieties. How do charging equilibria, aka charge regulation, then affect the electrostatic interactions? This is a fundamental problem in biophysics, important for our understanding of interactions between the proteins and proteinaceous aggregates such as viral capsids, but also in the general colloid context, often built on the fictional foundation of fixed charges.
Recent advances in the theoretical formulation and analysis of charge regulated system lead to some far reaching conclusions on electrostatic interactions in colloid milieu, that often differ fundamentally from the accepted wisdom.
I will present several examples of novel behavior or new understanding of the known behavior that is specifically connected with the response of the charging equilibrium on (bio)colloidal surfaces to the local bathing solution conditions.