Zernike Colloquium - Stephen Mann : Towards synthetic cellularity via protocell design and construction
|When:||Th 01-10-2015 15:00 - 16:00|
|Where:||Lecture Hall: 5111.0080|
Centre for Protolife Research
Centre for Organized Matter Chemistry
School of Chemistry
University of Bristol
The design and construction of compartmentalized chemical ensembles for modelling complex biological systems, exploring the origin of life, and advancing future living technologies is attracting considerable interest in a wide range of research communities.
In this talk, I will review some recent experiments undertaken in my laboratory that provide steps towards synthetic cellularity using bioinspiredchemistry principles and techniques.
I will discuss four new protocell models based on;
(ii) interfacial assembly of protein-polymer nanoconjugates (proteinosomes),
(iii) micro-droplet formation (coacervation), and hybrids of the above.
I will use these new model systems to discuss pathways towards chemical cognition, modulated reactivity and basic cellularity in compartmentalized artificial micro-ensembles.