Sebastian Beil’s Veni project “Lighting the way of drug discovery: photochemical synthesis of non-natural amino acids” has been granted by the Dutch Research Council (NWO).
In this project, mild photochemical methodologies will be developed to produce α-, β-, and γ-functionalized non-natural amino acids in single steps from inexpensive naturally occuring starting materials. To do so, theory and mechanistic investigations, as inherent design principles, will be combined with high-throughput screening of reaction conditions to provide a diverse library of non-natural amino acids as ready-to-use building blocks for incorporation into drug molecules which target bacterial infections, blood platelet aggregation, or the coronavirus. The obtained non-natural amino acids will allow new concepts toward the synthesis of alkaloid natural products that are not accessible with current methodologies.
Prof. Moniek Tromp has been appointed Captain of Science of the Chemistry Top Sector by the Minister of Economic Affairs and Climate Policy. As from 1 July 2023, she succeeded Prof. Bert Weckhuysen from Utrecht University.
Leonardo Arriagada Beltran conducted his PhD research on the interface of computer-generated art and the constantly evolving field of Artificial Intelligence (AI). He will defend his Phd thesis on 21 September. His research offers valuable insights...
Harish Vedantham and Casper van der Kooi have been nominated by New Scientist for Wetenschapstalent 2023 (Science Talent 2023). This election is meant to give young scientists and their research a stage.
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