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Publicaties 2011

Wetenschappelijke Publicaties 2011
  1. van Midwoud PM, Janssen J, Merema MT, de Graaf IAM, Groothuis GMM, Verpoorte E. Online HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices. Analytical Chemistry, 2011; 83(1):84-91.
  2. Khan AA, Chow ECY, Porte RJ, Pang KS, Groothuis GMM. The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices. Toxicology in Vitro, 2011; 25(1):80-90.      
  3. Chow ECY, Sondervan M, Jin C, Groothuis GMM, Pang KS. Comparative effects of doxercalciferol (1α-hydroxyvitamin D2) versus calcitriol (1α,25-dihydroxyvitamin D3) on the expression of transporters and enzymes in the rat in vivo. Journal of Pharmaceutical Sciences, 2011; 100(4):1594-1604.    
  4. Chen KT, Malo MS, Beasley-Topliffe LK, Poelstra K, Millan JL, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, Hodin RA. A role for intestinal alkaline phosphatase in the maintenance of local gut immunity. Digestive Diseases and Sciences, 2011; 56(4):1020-1027.  
  5. Rachmawati H, Beljaars L, Reker-Smit C, Bakker HI, Van Loenen-Weemaes AM, Lub-De Hooge MN and Poelstra K. Intravenous administration of recombinant human IL-10 suppresses the development of anti-Thy 1-induced glomerulosclerosis in rats. PDA Journal of Pharmaceutical Science and Technology, 2011; 65(2):116-130.
  6. Melgert BN, ten Hacken NH, Rutgers B, Timens W, Postma DS, Hylkema MN. More alternative activation of macrophages in lungs of asthmatic patients. Journal of Allergy and Clinical Immunology, 2011; 127(3):831-833.Notes: Letter to the Editor.
  7. Smelt MJ, de Haan BJ, Faas MM, Melgert BN, de Haan A, de Vos P. Effects of acute cytomegalovirus infection on rat islet allograft survival. Cell transplantation, 2011; 20(8):1271-1283.      
  8. Van Midwoud PM, Merema MT, Verweij N, Groothuis GMM, Verpoorte E. Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity, Biotechnology and Bioengineering, 2011; 108(6):1404-1412.          
  9. Van Midwoud PM, Verpoorte E, Groothuis GMM. Microfluidic devices for in vitro studies on liver drug metabolism and toxicity. Integrative Biology: quantitative biosciences from nano to macro, 2011; 3(5):509-521.            
  10. Fattahi F, Hylkema MN, Melgert BN, Timens W, Postma DS, ten Hacken NHT. Smoking and nonsmoking asthma: differences in clinical outcome and pathogenesis. Expert Review of Respiratory Medicine, 2011; 5(1):93-105.
  11. Van Beuge M, Prakash J, Lacombe M, Gosens R, Post E, Reker-Smit C, Beljaars L, Poelstra K. Reduction of fibrogenesis by selective delivery of a Rho-kinase inhibitor to hepatic stellate cells in mice. The Journal of Pharmacology and Experimental Therapeutics, 2011; 337(3):628-635.                                                                                                                                                                                                                                                                                                                                                                
  12. van der Meer AF, Marcus MAE, Touw DJ, Proost JH, Neef C. Optimal sampling strategy development methodology using maximum a posteriori Bayesian estimation. Therapeutic Drug Monitoring, 2011; 33(2):133-146.
  13. Elferink MGL, Olinga P, van Leeuwen EM, Bauerschmidt S, Polman J, Schoonen WG, Heisterkamp SH, Groothuis GMM. Gene expression analysis of precision-cut human liver slices indicate stable expression of ADME-Tox related genes. Toxicology and Applied Pharmacology, 2011; 253(1):57-69.                                                                                                                                                  
  14. van Beuge MM, Prakash J, Lacombe M, Post E, Reker-Smit C, Beljaars L, Poelstra K. Increased liver uptake and reduced hepatic stellate cell activation with a cell-specific conjugate of the Rho-kinase inhibitor Y27632. Pharmaceutical Research, 2011; 28(8):2045-2054.                                                                                                                        
  15. Meijer DKF. Transport and metabolism in the hepatobiliary system. Comprehensive Physiology, January 2011; 717-758. Notes: Online Publication. Source: Handbook of Physiology, the Gastrointestinal System, Salivary, Gastric, Pancreatic, and Hepatobiliary Secretion, originally published in 1989.
  16. Bansal R, Prakash J, Post E, Beljaars L, Schuppan D, Poelstra K. Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice. Hepatology, 2011; 54(2):586-596.                                                                                                    
  17. Poelstra K, Schuppan D. Targeted therapy of liver fibrosis/cirrhosis and its complications. Journal of Hepatology, 2011; 55(3):726-728.
  18. Coppens MJ, Eleveld DJ, Proost JH, Marks LAM, Van Bocxlaer JFP, Vereecke H, Absalom AR, Struys MMRF. An evaluation of using population pharmacokinetic models to estimate pharmacodynamic parameters for propofol and bispectral index in children. Anesthesiology, 2011; 115(1):83-93. Notes: Publication from the Department of Anesthesiology.
  19. Bansal R, Post E, Proost JH, de Jager-Krikken A, Poelstra K, Prakash J. PEGylation improves pharmacokinetic profile, liver uptake and efficacy of interferon gamma in liver fibrosis. Journal of Controlled Release, 2011; 154(3):233-240.                    
  20. Johnson M, Kozielska M, Pilla Reddy V, Vermeulen A, Li C, Grimwood S, de Greef R, Groothuis GMM, Danhof M, Proost JH. Mechanism-based pharmacokinetic-pharmacodynamic modeling of the dopamine D2 receptor occupancy of olanzapine in rats. Pharmaceutical Research, 2011; 28(10):2490-2504.
  21. Pilla Reddy V, Kozielska M, Johnson M, Vermeulen A, de Greef R, Liu J, Groothuis GMM, Danhof M, Proost JH. Structural models describing placebo treatment effects in schizophrenia and other neuropsychiatric disorders. Clinical Pharmacokinetics, 2011; 50(7):429-450.
  22. Wisastra R, Poelstra K, Bischoff R, Maarsingh H, Haisma HJ, and Dekker FJ. Antibody-free detection of protein tyrosine nitration in tissue sections. ChemBioChem, 2011; 12(13):2016-2020. Communications.                                                                                   
  23. Punt A, Schiffelers M-JWA, Horbach GJ, van de Sandt JJM, Groothuis GMM, Rietjens IMCM and Blaauboer BJ. Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice. Regulatory Toxicology and Pharmacology, 2011; 61(1):105-114.
  24. Bansal R, Prakash J, De Ruiter M, Beljaars L, Poelstra K. Peptide modified-albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis. Molecular Pharmaceutics, 2011; 8(5):1899-1909.
  25. Jayaraman R, Pilla Reddy V, Khalid Pasha M, Wang H, Sangthongpitag K, Yeo P, Hu CY, Wu X, Xin L, Goh E, New LS, Ethirajulu K. Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase (HDAC) inhibitor, and prediction of human pharmacokinetics. Drug Metabolism and Disposition, 2011; 39(12):2219-2232.
  26. Franks,I. Liver: Modified interferon γ targets key cells responsible for liver fibrogenesis. Nature Reviews Gastroenterology and Hepatology, 2011; 8(7):359. Research Highlight, Comment on the article: Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice, Hepatology 2011; 54(2): 586-596, by Bansal R, Prakash J, Post E, Beljaars L, Schuppan D, Poelstra K.
  27. van Midwoud PM, Merema MT, Verpoorte E, Groothuis GMM. Microfluidics enables small-scale tissue-based drug metabolism studies with scarce human tissue. Journal of Laboratory Automation, 2011; 16(6):468-476.
  28. de Jong E, Winkel P, Poelstra K, Prakash J. Anticancer effects of 15d-prostaglandin-J2 in wild-type and doxorubicin-resistant ovarian cancer cells: Novel actions on SIRT1 and HDAC. PLoS ONE, 2011; 6(9):e25192.
  29. Szalowska E, Dijkstra M, Elferink MGL, Weening D, de Vries M, Bruinenberg M, Hoek A, Roelofsen H, Groothuis GMM, Vonk RJ. Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and candidate biomarkers. BioMed Central Medical Genomics, 2011; 4:71.
  30. Eleveld DJ, Proost JH, Absalom AR, Struys MMRF. Obesity and allometric scaling of pharmacokinetics. Clinical Pharmacokinetics, 2011; 50(11):751-763.  Notes: Publication from the Department of Anesthesiology, University Medical Center Groningen, the Netherlands. Commentary on the Article: van Kralingen S, Diepstraten J, Peeters MYM, Deneer VHM, van Ramshorst B, Wiezer RJ, van Dongen EPA, Danhof M, Knibbe CAJ. Population pharmacokinetics and pharmacodynamics of propofol in morbidly obese patients. Clinical Pharmacokinetics 2011; 50(11): 739-750. The Author’s Reply: Diepstraten J, Knibbe CAJ. The author’s reply: Obesity and allometric scaling of pharmacokinetics. Clinical Pharmacokinetics 2011; 50(11): 755-756.
  31. Prakash J. Potential application of peptides in tumor targeting and anticancer therapeutics. Current Pharmaceutical Biotechnology, 2011; 12(8):1087-1088.  Notes: Editorial. Guest Editor of special issue on the applications of peptides for tumor targeting and as anticancer therapies.
  32. Faas MM, de Vos P, Melgert BN. Sex hormones and immunoregulation. Review article. Electronic Publication: BrainImmune, Bridging Neurosciences and Immunology. Published on 12 July 2011, 25 Pages. http://brainimmune.org/index.php?
  33. Stepanenko IN, Casini A, Edafe F, Novak MS, Arion VB, Dyson PJ, Jakupec MA, and Keppler BK. Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells. Inorganic Chemistry, 2011; 50(24):12669-12679.
  34. Blanckenburg B. Toxische afbraak. Chemisch2Weekblad, supplement C2W medicines, 2011.  Notes: Interview met Prof. Dr. G.M.M. Groothuis door Bo Blanckenburg.
  35. Rijnvis D. Proefdier van de toekomst: Homo sapiens. Intermediair, 2011; 44, 4 November 2011:34-37. Notes: Interview met Prof. Dr. G.M.M. Groothuis en Prof. dr. E.M.J. Verpoorte door Dennis Rijnvis.
Laatst gewijzigd:05 maart 2024 14:53
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