Systems-wide Studies Uncover Commander, a Multiprotein Complex Essential to Human Development
Here, we review the synergy between large-scale proteomic efforts and focused studies in the discovery of Commander, describe its composition, structure, and function, and discuss how it illustrates the power of systems biology. Based on 3D modeling and biochemical data, we draw strong parallels between Commander and the retromer cargo-recognition complex, laying a foundation for future research into Commander's role in human developmental disorders.
| Last modified: | 29 May 2017 2.48 p.m. |
More news
-
02 July 2025
Relinde Weil reappointed as a member of the Supervisory Board UG
The Minister of Education has reappointed Relinde Weil for a second term as a member of the Supervisory Board of the University of Groningen.
-
-
01 July 2025
Khalaf Alkhalaf elected Alumnus of the Year 2025
Khalaf Alkhalaf has been elected Alumnus of the Year 2025 by the University of Groningen. He has received the award for his commitment to providing good care and guidance to refugees in the Netherlands and the inspiring way in which he shares his...