Skip to ContentSkip to Navigation
About us Medical Sciences Research Pediatrics
University Medical Center Groningen

Preview Cell Metabolism – not all is bad about lithocholic acid

04 March 2020
Cell Metab 2020
Cell Metab 2020

Microbiome Modulation of the Host Adaptive Immunity through Bile Acid Modification

Folkert Kuipers, Jan Freark de Boer, Bart Staels

The microbiome is well known to influence the immune response of the host. Song et al. now show that the microbiome modulates adaptive immunity in mice through formation of bile acid species acting on RORγ + regulatory T cells via the Vitamin D Receptor, thereby lowering the vulnerability for chemically induced colitis.

Free access (April 22,2020):

Last modified:04 March 2020 10.34 a.m.

More news

  • 14 February 2023

    Lift to the inclusive workplace

    There is plenty of work, and yet people with a disability are still often sidelined. One plus one is two, or so you’d think: this is the perfect time to help this group of workers find a job. The intention is there, also within the University, but...

  • 15 December 2022

    Groningen contributes to major research initiative into energy-efficient information technology

    The Dutch science funding agency NWO recently awarded a large research project into new concepts for energy-efficient information technology of no less than ten million euros

  • 05 December 2022

    Frans J. Sijtsma new Director Agricola School

    On the recommendation of the Board of the University of Groningen, Dr Frans J. Sijtsma has been appointed as academic director of the Rudolf Agricola School for Sustainable Development with effect from 1 February 2023. This concerns a 0.5 FTE...