Preview Cell Metabolism – not all is bad about lithocholic acid
Microbiome Modulation of the Host Adaptive Immunity through Bile Acid Modification
Folkert Kuipers, Jan Freark de Boer, Bart Staels
The microbiome is well known to influence the immune response of the host. Song et al. now show that the microbiome modulates adaptive immunity in mice through formation of bile acid species acting on RORγ + regulatory T cells via the Vitamin D Receptor, thereby lowering the vulnerability for chemically induced colitis.
https://doi.org/10.1016/j.cmet.2020.02.006
Free access (April 22,2020): https://authors.elsevier.com/a/1agGV5WXUlIcPm
| Last modified: | 04 March 2020 10.34 a.m. |
More news
-
16 April 2024
UG signs Barcelona Declaration on Open Research Information
In a significant stride toward advancing responsible research assessment and open science, the University of Groningen has officially signed the Barcelona Declaration on Open Research Information.
-
02 April 2024
Flying on wood dust
Every two weeks, UG Makers puts the spotlight on a researcher who has created something tangible, ranging from homemade measuring equipment for academic research to small or larger products that can change our daily lives. That is how UG...
-
18 March 2024
VentureLab North helps researchers to develop succesful startups
It has happened to many researchers. While working, you suddenly ask yourself: would this not be incredibly useful for people outside of my own research discipline? There are many ways to share the results of your research. For example, think of a...