Skip to ContentSkip to Navigation
About us Medical Sciences Research Pediatrics
University Medical Center Groningen

Preview Cell Metabolism – not all is bad about lithocholic acid

04 March 2020
Cell Metab 2020
Cell Metab 2020

Microbiome Modulation of the Host Adaptive Immunity through Bile Acid Modification

Folkert Kuipers, Jan Freark de Boer, Bart Staels

The microbiome is well known to influence the immune response of the host. Song et al. now show that the microbiome modulates adaptive immunity in mice through formation of bile acid species acting on RORγ + regulatory T cells via the Vitamin D Receptor, thereby lowering the vulnerability for chemically induced colitis.

https://doi.org/10.1016/j.cmet.2020.02.006

Free access (April 22,2020): https://authors.elsevier.com/a/1agGV5WXUlIcPm

Last modified:04 March 2020 10.34 a.m.

More news

  • 10 July 2020

    ENLIGHT recognized as a European University

    The ENLIGHT consortium of nine European universities, including the University of Groningen, was selected within the framework of the second call for ‘European Universities’, the European Commission's pilot program for new multilateral networks....

  • 08 July 2020

    Piekopvang in Groningen voorbereid voor internationale studenten

    Aan het einde van de zomer komen er naast veel Nederlandse studenten ook internationale studenten naar Groningen om voor kortere of langere tijd te studeren aan de Hanzehogeschool Groningen (HG) of de Rijksuniversiteit Groningen (RUG). Vanwege de...

  • 01 July 2020

    Sander de Hosson elected Alumnus of the Year 2019

    Lung doctor Sander de Hosson has been elected Alumnus of the Year 2019 by the University of Groningen. He is receiving the award for the incisive way in which he calls for attention for the emotional side of palliative care and for making death a...