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Research Pediatrics
University Medical Center Groningen

New key publication: Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

11 October 2018
Cell Metabolism 2018
Cell Metabolism 2018

The autoimmune attack of β-cells is a hallmark of type 1 diabetes (T1D), but the events culminating in the specific loss of the insulin-secreting cells remain poorly understood. In collaboration with the group of Romano Regazzi (University of Lausanne, Switzerland), we provide evidence for the involvement of an exosome-mediated transfer of miRNAs from T lymphocytes to β-cells in the initial phases of T1D development.

Link to : CELL Metabolism

Last modified:15 October 2018 1.01 p.m.

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