
New key publication: Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

The autoimmune attack of β-cells is a hallmark of type 1 diabetes (T1D), but the events culminating in the specific loss of the insulin-secreting cells remain poorly understood. In collaboration with the group of Romano Regazzi (University of Lausanne, Switzerland), we provide evidence for the involvement of an exosome-mediated transfer of miRNAs from T lymphocytes to β-cells in the initial phases of T1D development.
Link to : CELL Metabolism
Last modified: | 15 October 2018 1.01 p.m. |
More news
-
14 February 2023
Lift to the inclusive workplace
There is plenty of work, and yet people with a disability are still often sidelined. One plus one is two, or so you’d think: this is the perfect time to help this group of workers find a job. The intention is there, also within the University, but...
-
15 December 2022
Groningen contributes to major research initiative into energy-efficient information technology
The Dutch science funding agency NWO recently awarded a large research project into new concepts for energy-efficient information technology of no less than ten million euros
-
05 December 2022
Frans J. Sijtsma new Director Agricola School
On the recommendation of the Board of the University of Groningen, Dr Frans J. Sijtsma has been appointed as academic director of the Rudolf Agricola School for Sustainable Development with effect from 1 February 2023. This concerns a 0.5 FTE...