PhD defence Marleen Linzke
|When:||Fr 20-12-2019 09:00 - 10:00|
Morphologic analysis of the apicoplast formation in Plasmodium falciparum
Malaria, caused by Plasmodium spp., remains with more than 400.000 deaths per year one of the most severe infectious diseases worldwide. Increasing drug resistance against the available antimalarial drugs poses a great threat in combating and eradication of this disease and new drug targets are greatly needed. the research of Marleen Linzke has been aimed on the apicoplast. The apicoplast is a chloroplast-like organelles of the Plasmodium parasite has been shown to be essential for the parasite survival and offers new drug target to exploit. How the parasite distributes this essential organelle during the asexual replication has been an open question up to this point. Identifying and understanding the mechanism might open up the road to new drug targets to target the parasite.
Promotores: Prof.dr. A.S.S. Dömling and Prof.dr. C. Wrenger