PhD defence J. Han
|When:||Fr 07-02-2020 11:00 - 12:00|
Bioconjugation of metal-based compounds for targeted biomedical applications: from drug delivery to mass spectrometry imaging.
This thesis described the synthesis, characterization, and application of bioconjugated metal-based compounds. The bioconjugated Pd-based metallocages are non-toxic to healthy tissue cells. Their well-defined structure makes them ideal tools for targeted delivery of anticancer drug cisplatin. The bioconjugated Ru-based compounds exhibit high photocleavable property which can be used as mass-tag for the targeted mass spectrometry imaging of tumor tissue.
Promotores: Prof.dr. P.L. Horvatovich and Prof.dr. R.P.H. Bischoff and Prof.dr. A. Casini