DNA Microarray Facility for Gram+ Bacteria
The DNA Microarray Facility for Gram+ Bacteria is an advanced and validated in-house DNA microarray facility that is fully operational within the research group Molecular Genetics. This facility includes advanced liquid-liquid handling robotics, a DNA-arrayer, a hybridization station, laser scanner for data acquisition, and several servers for subsequent advanced bioinformatics analyses of the results. DNA microarrays are made in-house and contain amplified DNA fragments of all the genes of Bacillus subtilis (strain 168), B. cereus (type strain), Lactococcus lactis (strains IL1403 and MG1363), and Streptococcus pneumoniae (strains TIGR4 and R6). This facility provides unique opportunities for transcriptome analysis as part of the functional genomics studies of Gram+ bacteria, especially to explore and to visualize complex regulatory gene networks. The current expertise has resulted in collaborative research projects on functional and comparative genomics of Gram+ bacteria with industries and several larger Dutch and international research programmes.
| Last modified: | 02 October 2012 4.40 p.m. |