Colloquium Computer Science, Dr. Petra Schneider
|
Date: |
Wednesday, October 15th 2014 |
|
Speaker: |
Dr. Petra Schneider, |
|
Room: |
5161.0267 (Bernoulliborg) |
|
Time: |
16.00 |
Title: Computational analysis of human- and mouse-specific next-generation sequencing data in mixed tissue samples
Abstract:
Blackfield is a young biotechnology company supporting pharmaceutical
companies in developing targeted cancer drugs. We offer to derive
genetic tumor profiles from next-generation sequencing (NGS) data.
Computational analysis of the raw sequencing data using proprietary
algorithms is a key step in this process, due to the massive amount of
data generated by NGS platforms. In this talk, I will outline the
generation and analysis of NGS data, and I will present the novel
strategy we integrated recently in our computational analysis pipeline
to deal with contaminated tumor samples. Artificial validation samples
demonstrate in a controlled setting how this approach influences
mutation calling or gene expression analyses.
Colloquium coordinators are Prof.dr. M. Aiello (e-mail :
M.Aiello rug.nl
) and
Prof.dr. M. Biehl (e-mail:
M.Biehl rug.nl
)
http://www.rug.nl/research/jbi/news/colloquia/computerscience
| Last modified: | 07 June 2018 10.59 a.m. |
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