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Research Bernoulli Institute Calendar Colloquia - Computer Science

Colloquium Computer Science, Dr. Petra Schneider

15 October 2014

Date:                      

Wednesday, October 15th 2014

Speaker:

Dr. Petra Schneider,
Blackfield AG, Germany

Room:

5161.0267 (Bernoulliborg)

Time:

16.00

Title: Computational analysis of human- and mouse-specific next-generation sequencing data in mixed tissue samples    


Abstract:

Blackfield is a young biotechnology company supporting pharmaceutical
companies in developing targeted cancer drugs. We offer to derive
genetic tumor profiles from next-generation sequencing (NGS) data.
Computational analysis of the raw sequencing data using proprietary
algorithms is a key step in this process, due to the massive amount of
data generated by NGS platforms. In this talk, I will outline the
generation and analysis of NGS data, and I will present the novel
strategy we integrated recently in our computational analysis pipeline
to deal with contaminated tumor samples. Artificial validation samples
demonstrate in a controlled setting how this approach influences
mutation calling or gene expression analyses.

Colloquium coordinators are Prof.dr. M. Aiello (e-mail : M.Aiello rug.nl ) and
Prof.dr. M. Biehl (e-mail: M.Biehl rug.nl )

http://www.rug.nl/research/jbi/news/colloquia/computerscience

Last modified:07 June 2018 10.59 a.m.

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