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Research Bernoulli Institute Calendar Colloquia - Computer Science

Colloquium Computer Science, Dr. Petra Schneider

15 October 2014


Wednesday, October 15th 2014


Dr. Petra Schneider,
Blackfield AG, Germany


5161.0267 (Bernoulliborg)



Title: Computational analysis of human- and mouse-specific next-generation sequencing data in mixed tissue samples    


Blackfield is a young biotechnology company supporting pharmaceutical
companies in developing targeted cancer drugs. We offer to derive
genetic tumor profiles from next-generation sequencing (NGS) data.
Computational analysis of the raw sequencing data using proprietary
algorithms is a key step in this process, due to the massive amount of
data generated by NGS platforms. In this talk, I will outline the
generation and analysis of NGS data, and I will present the novel
strategy we integrated recently in our computational analysis pipeline
to deal with contaminated tumor samples. Artificial validation samples
demonstrate in a controlled setting how this approach influences
mutation calling or gene expression analyses.

Colloquium coordinators are Prof.dr. M. Aiello (e-mail : M.Aiello ) and
Prof.dr. M. Biehl (e-mail: M.Biehl )

Last modified:07 June 2018 10.59 a.m.

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