Skip to ContentSkip to Navigation
About us Latest news News News articles

Anika Nagelkerke awarded KWF Research Grant

25 August 2022
Dr. Anika Nagelkerke
Dr Anika Nagelkerke

Dr Anika Nagelkerke (University of Groningen / GRIP - Pharmaceutical Analysis)

‘A novel liquid biopsy assay to select cancer patients for hypoxia-modifying treatment’

Dr Anika Nagelkerke is an assistant professor of cell biology, biochemistry & molecular biology and oncology. Her research project is entitled ‘A novel liquid biopsy assay to select cancer patients for hypoxia-modifying treatment’, and aims to improve existing methods.

Many solid tumours have an oxygen deficiency (hypoxia), making their progression more aggressive. Although being able to determine the degree of hypoxia before starting treatment could be enormously beneficial, the current methods for doing this are not ideal. The aim of this project is therefore to explore alternative, clinically viable methods.

The project itself involves studying whether the extracellular vesicles (EVs) excreted by cells could serve as an indicator for the degree of hypoxia in the tumour. These vesicles are excreted by all body cells, including tumour cells. It would appear that the vesicles reflect the cells from which they originate, making them a frontrunner in terms of new biomarkers for cancer. Nagelkerke hopes that her research project will contribute to the KWF mission to stimulate better treatment methods for cancer. Developing a method that can be used to measure tumour hypoxia before, and during, treatment could enable doctors to choose the most suitable treatment option, thereby improving the effectiveness of the treatments currently being used.

Last modified:15 February 2023 4.16 p.m.

More news

  • 04 March 2024

    A plant-based sensor

    Every two weeks, UG Makers puts the spotlight on a researcher who has created something tangible, ranging from homemade measuring equipment for academic research to small or larger products that can change our daily lives. That is how UG...

  • 11 December 2023

    Join the 'Language and AI' community

    As a part of the Jantina Tammes School, the 'Language and AI' theme is an interdisciplinary initiative that aims to encourage collaboration among academics, PhD candidates, students, and industry representatives who share a keen interest in the...

  • 13 October 2023

    Moniek Tromp appointed Captain of Science of the Top Sector Chemistry

    Prof. Moniek Tromp has been appointed Captain of Science of the Chemistry Top Sector by the Minister of Economic Affairs and Climate Policy. As from 1 July 2023, she succeeded Prof. Bert Weckhuysen from Utrecht University.