The effect of inhibition of EGFR transactivation in renal (patho)physiological processes

PhD ceremony: Ms. G.M. Mulder, 16.15 uur, Academiegebouw, Broerstraat 5, Groningen

Dissertation: The effect of inhibition of EGFR transactivation in renal (patho)physiological processes

Promotor(s): prof. H. van Goor, prof. J.L. Hillebrands

Faculty: Medical Sciences

This thesis explored and emphasized the role of the EGFR transactivation pathway in renal physiology and pathophysiological processes. Inhibition of the EGFR activation pathway can be a suitable intervention therapy during and after renal transplantation and in the treatment of (cardiovascular complications in) renal diseases. New drugs that interfere in the EGFR activation pathway can possibly contribute to reducing the rejection risk following renal transplantation and be useful in the treatment of renal diseases.