Skip to ContentSkip to Navigation
About usNews and EventsNews articles

A wide-field view at single molecules and single particles

21 October 2011

PhD ceremony: Mr. F. Lusitani, 12.45 uur, Aula Academiegebouw, Broerstraat 5, Groningen

Dissertation: A wide-field view at single molecules and single particles

Promotor(s): prof. P.H.M. van Loosdrecht

Faculty: Mathematic and Natural Sciences

Optical microscopy is among the oldest techniques developed and implemented for modern science; the first microscope dating back to the end of the sixteenth century. Throughout 5 centuries, scientists have greatly benefitted from the remarkable possibilities offered by the observation of nature at small scales in a number of disciplines ranging from biology to medicine and from condensed matter physics to optics. The quest to increase sensitivity and resolution towards smaller and smaller scales, provoked by the demand to gain a much more detailed understanding of the microscopic world, has over the years led to a boost of the capabilities of microscopic techniques, which is continuing even today.

Five centuries of theoretical understanding and technological improvements have provided modern scientist the possibility to study matter at the single molecule level. The single molecule and single particle microscopy techniques developed in the last 20 years and subject of this dissertation, has extended the applications of optical microscopies to new fields such as nanotechnology and material science. Modern single molecule microscopy has provided, and still does, scientists with a powerful tool in the quest of investigating matter at the smallest length scales. How to achieve single molecule sensitivity, how the light behaves when emitted by a single molecule, and how the imaging process occurs are largely discussed in this dissertation together with a number of examples where the technique is applied to the investigation of diverse systems and conditions.

Last modified:15 September 2017 3.41 p.m.

More news

  • 23 April 2019

    From paperclip to patent

    How is it possible that an albatross doesn’t crash and die when it lands? And how come its large wings don’t break due to air resistance? That is what you would expect, according to the laws of aerodynamics. However, Professor Eize Stamhuis has discovered...

  • 17 April 2019

    Why lightning often strikes twice

    In contrast to popular belief, lightning often does strike twice, but the reason why a lightning channel is ‘reused’ has remained a mystery. Now, an international research team led by the University of Groningen has used the LOFAR radio telescope to...

  • 16 April 2019

    Still going strong after four decades

    On March 29th professor of Applied Physics Jeff de Hosson was offered a farewell symposium, a few months after his official retirement date near the close of 2018. ‘But 29 March was the 100th birthday of Jan Francken, my predecessor.’ Besides, De Hosson...