Influence of metal-on-metal wear on infection in hip arthropasty
PhD ceremony: Mr. A.H. Hosman, 14.30 uur, Aula Academiegebouw, Broerstraat 5, Groningen
Dissertation: Influence of metal-on-metal wear on infection in hip arthropasty
Promotor(s): prof. H.J. Busscher, prof. H.C. van der Mei, prof. S.K. Bulstra
Faculty: Medical Sciences
The main goal of this thesis was to determine the influence of wear particles from metal-on-metal hip prostheses (MOM-prostheses) on deep infections. From our research in MOM wear and bacteria we concluded that in vitro bacterial growth is inhibited, and in vivo the immune system. Finally, revisions of the 2720 Australian national joint replacement registry were examined, especially focusing on the infection data from MOM versus metal-on-plastic hip prostheses (MOP-prostheses). The cumulative 8-year revision risk of infection was 1.2% for MOM prostheses and 0.8% for MOP prostheses. We conclude that Co-Cr particles may hamper the functioning of macrophages and that this may lead to an increased risk of a prolonged presence of bacteria after surgery compared with MOP-particles.
| Last modified: | 13 March 2020 01.12 a.m. |
More news
-
05 March 2025
Women in Science
The UG celebrates International Women’s Day with a special photo series: Women in Science.
-
28 February 2025
Vici grants for two UG/UMCG scientists
The Dutch Research Council (NWO) has awarded Vici grants, worth up to €1.5 million each, to Merel Keijzer and Charalampos Tsoumpas This will enable the researchers to develop an innovative line of research and set up their own research group for...
-
11 February 2025
Space for your disability
When it comes to collaborations between researchers from different faculties, the UG is at the top of its game. A prime example is the Disabled City project that researches how the mobility of people with a physical disability can be explored...