Skip to ContentSkip to Navigation
About usNews and EventsNews articles

Biodegradable plates and screws in oral and maxillofacial surgery

14 September 2011

PhD ceremony: Mr. G.J. Buijs, 16.15 uur, Aula Academiegebouw, Broerstraat 5, Groningen

Dissertation: Biodegradable plates and screws in oral and maxillofacial surgery

Promotor(s): prof. R.R.M. Bos, prof. B. Stegenga, prof. G.J. Verkerke

Faculty: Medical Sciences

 

Metallic plates and screws are used for immobilization of bone fragments in trauma and orthognathic surgery. Some authors advocate the removal of metallic plates and screws because of potential adverse reactions. Biodegradable fixation systems could reduce or even delete the problems associated with metallic systems since removal is not necessary. The aim of this thesis was to establish the effectiveness and safety of biodegradable plates and screws as a potential alternative to metallic ones. Based on a systematic review it was concluded that there is insufficient scientific evidence for safe and effective use of biodegradable plates and screws in maxillofacial fracture and osteotomies. Furthermore, it was found that the in vitro mechanical properties of titanium plates and screws are superior compared to their biodegradable counterparts. The results of a multi-center randomized clinical trial showed no difference for bone healing 8-weeks after surgery. Despite the ‘non inferior’ primary outcome result, the benefits of using biodegradable systems (less plate removal operations) need to be demonstrated in a long-term follow-up study.

  

Last modified:15 September 2017 3.40 p.m.

More news

  • 16 April 2019

    A thorough characterization of structural variants in human genomes

    Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or “spelling mistakes” in the DNA sequence, but even more variation comes from structural variants, which include additions, deletions...

  • 02 April 2019

    ‘Sense of loss drives voting behaviour’

    ‘Everybody here loves that academia has returned to Friesland. We teach, carry out research and think along about solutions to problems that are relevant for Friesland,’ says Caspar van den Berg, Professor of Global and Local Governance at the UG Campus...

  • 02 April 2019

    UMCG onderzoekt behandeling tegen geheugenachteruitgang ouderen

    Is het mogelijk om achteruitgang van geheugen en denkvermogen bij ouderen te remmen door hun hersenen letterlijk actiever te maken? Kan stimulatie met zwakke stroompjes op de schedel de veerkracht van hersenen versterken? Hersenonderzoekers van het...