PhD ceremony: Ms. G. Onuta, 14.45 uur, Doopsgezinde kerk, Oude Boteringestraat 33, Groningen
Dissertation: Transplant arteriosclerosis and in-stent restenosis. Experimental studies on pathomechanisms and therapeutic intervention
Promotor(s): prof. J.L. Hillebrands, prof. F.G.M. Kroese
Faculty: Medical Sciences
The aim of the studies was to investigate the various cellular and molecular mechanisms underlying the narrowing of the blood vessels in transplanted organs (transplant arteriosclerosis [TA]) and after stenting (in-stent restenosis [ISR]), using both in vivo and in vitro preclinical models. TA and ISR represent two major macrovascular occlusive diseases characterized by endothelial cell damage, inflammation and neointima (NI) formation. At present there are no efficacious therapeutic measure to control their onset and evolution. Focus of this thesis was therefore to obtain more insight on post-injury endothelium regeneration, the origin of NI smooth muscle cells (SMCs) and factors responsible for SMC recruitment/proliferation in TA and ISR.
Many major Dutch companies publish extensive information about climate impact in their annual reports. However, very few companies provide concrete, detailed information about their own CO2 emissions, the impact of climate change on their business...
De NWO heeft aan 37 out-of-the-box onderzoeksideeën financiering toegekend vanuit de Ideeëngenerator. Een belangrijk kenmerk van de projecten is een mogelijke maatschappelijke impact. Elk van de onderzoekers krijgt 50.000 euro beschikbaar om met samen...
The University of Groningen (UG) has permanently closed the project aimed at creating a branch campus in Yantai. Discussions were held with China Agricultural University, the city of Yantai and the Province of Shandong.