Amplitude integrated EEG. Longitudinal recordings in critically ill newborns

PhD ceremony: Mr. H.J. ter Horst, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen

Title: Amplitude integrated EEG. Longitudinal recordings in critically ill newborns

Promotor(s): prof. A.F. Bos

Faculty: Medical Sciences

Critically ill newborns are at risk of developing brain injury and monitoring their brain function is essential. Two techniques can be used: amplitude-integrated EEG (aEEG) and near infrared spectroscopy (NIRS). This thesis described the use of aEEG in a level III neonatal intensive care unit. It was demonstrated that aEEG is a valuable tool in monitoring brain function in term newborns with several conditions that are potentially damaging to the brain. It was also shown that continuing aEEG monitoring for longer time periods adds to its prognostic value. Digital equipment increases the ability to use aEEG monitoring and assessment becomes more accurate for both term and preterm infants. Combining the techniques of aEEG and NIRS gained more insight in brain function.