PhD ceremony: Ms. R. Altena, 14.45 uur, uur, Academiegebouw, Broerstraat 5, Groningen
Title: Chemotherapy-related cardiovascular morbidity in testicular cancer patients.
Markers & mechanisms
Promotor(s): prof. J.A. Gietema, prof. E.G.E. de Vries
Faculty: Medical Sciences
Since the introduction of platinum-based chemotherapy regimens in the late 1970s, testicular cancer has become a highly curable malignancy with a 10-year survival rate of 80%. As a result of this favourable prognosis, in addition to a still increasing incidence rate, the population of successfully treated testicular cancer survivors is growing. Treatment-related complications, in particular cardiovascular diseases, are increasingly recognised in this population. The aim of this thesis was to search for early biomarkers of subclinical treatment-related damage in testicular cancer patients treated with cisplatin-based chemotherapy. Increases in biomarkers for vascular damage were found, as well as increased damage to the heart and blood vessels. Possible targets for mechanisms that contribute to endothelial damage due to chemotherapy were also found. These findings may lead to early diagnosis of cardiovascular diseases in testicular cancer survivors and may facilitate their treatment.
Uit promotieonderzoek van Juliette Schuurmans blijkt dat het aanbieden van dragersschapstesten door getrainde huisartsen als verantwoord kan worden gezien.
Vera Heininga is the Open Science coordinator and future programme leader of the upcoming Open Science programme of the University of Groningen. Together with her colleagues, she created the Open Science Community Groningen (OSCG). She explains...
Individuals aged 75 and above who still have their natural dentition generally are in better health than those of the same age who are edentulous.
The UG website uses functional and anonymous analytics cookies. Please answer the question of whether or not you want to accept other cookies (such as tracking cookies).
If no choice is made, only basic cookies will be stored. More information