Skip to ContentSkip to Navigation
About usNews and EventsNews articles

Hemodynamic physiology during perioperative intracranial hypertension. Monitoring and therapeutic implications

27 April 2011

PhD ceremony: Mr. A.F. Kalmar, 13.15 uur, Academiegebouw, Broerstraat 5, Groningen

Title: Hemodynamic physiology during perioperative intracranial hypertension. Monitoring and therapeutic implications

Promotor(s): prof. M.M.R.F. Struys, prof. E.P. Mortier, prof. A.R Absalom

Faculty: Medical Sciences

 

New surgical treatment options, such as endoscopic neurosurgery, require adequate monitoring and management of the intracranial pressure, cerebral oxygenation and homeostasis. In this thesis a new methodology is described that significantly improves perioperative monitoring.

Endoscopic neurosurgical procedures may result in increased intracranial pressure and acute hemodynamic effects. It was shown that the initial phase of this so called Cushing reflex consists of a combination of hypertension and tachycardia. These clinical findings were confirmed in a rat-model of endoscopic neurosurgery, which resulted in the investigation of various methods to monitor the Cushing reflex. The newly developed method is significantly more precise as compared to the present approach.

 

 

Last modified:15 September 2017 3.41 p.m.

More news

  • 23 April 2019

    From paperclip to patent

    How is it possible that an albatross doesn’t crash and die when it lands? And how come its large wings don’t break due to air resistance? That is what you would expect, according to the laws of aerodynamics. However, Professor Eize Stamhuis has discovered...

  • 16 April 2019

    A thorough characterization of structural variants in human genomes

    Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or “spelling mistakes” in the DNA sequence, but even more variation comes from structural variants, which include additions, deletions...

  • 02 April 2019

    ‘Sense of loss drives voting behaviour’

    ‘Everybody here loves that academia has returned to Friesland. We teach, carry out research and think along about solutions to problems that are relevant for Friesland,’ says Caspar van den Berg, Professor of Global and Local Governance at the UG Campus...