Lateral mobility of proteins and peptides in membranes
PhD ceremony: Mr. S. Ramadurai, 16.15 uur, Academiegebouw, Broerstraat 5, Groningen
Thesis: Lateral mobility of proteins and peptides in membranes
Promotor(s): prof. B. Poolman
Faculty: Mathematics and Natural Sciences
Biological membranes are composed of various lipids species of different acyl chain lengths and head groups. The lateral organisation and mobility of bilayer spanning proteins depends on lipid environment. Lateral mobility of proteins play a crucial role in cellular processes. Theoretical framework on lateral mobility of proteins in membrane was proposed by Saffman-Delbrück. This pioneering work comprises that lateral mobility is weakly dependent on the radius of the proteins but strongly dependent on thickness and viscosity of the membrane. In this thesis, integral proteins with different radius and transmembrane peptides are reconstituted in the membrane composed of lipids with different acyl chain length and head groups, and there lateral mobility are experimentally determined by fluorescence correlation spectroscopy.
Last modified: | 13 March 2020 01.16 a.m. |
More news
-
17 July 2025
Veni-grants for eleven UG researchers
The Dutch Research Council (NWO) has awarded a Veni grant of up to €320,000 each to eleven researchers of the University of Groningen and the UMCG: Quentin Changeat, Wen Wu, Femke Cnossen, Stacey Copeland, Bart Danon, Gesa Kübek, Hannah Laurens, Adi...
-
14 July 2025
ERC Proof of Concept grant for Kottapalli and Covi
Professors Ajay Kottapalli and Erika Covi have received Proof of Concept grants from the European Research Council (ERC).
-
10 July 2025
Dutch Research Agenda funding for nanomedicine research
Prof Dr Anna Salvati, Dr Christoffer Åberg and Prof Dr Siewert-Jan Marrink have been granted a National Science Agenda (NWA) funding to further develop life-saving drugs based on nanotechnology with the NanoMedNL consortium.